DR4Dw4/DR53 molecules contain a peptide from the autoantigen calreticulin

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Association of the B-Cell Alloantigen DRw4 with Rheumatoid Arthritis

1978 • 1,170 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1992 • 763 citations

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

1993 • 383 citations

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.

1991 • 242 citations

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

1994 • 234 citations

Identification of a motif for HLA-DR1 binding peptides using M13 display libraries.

1992 • 224 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

Structure of peptides associated with MHC class I molecules

1994 • 200 citations

HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.

1993 • 154 citations

Characterization of the autoantigen calreticulin.

1991 • 132 citations

Distinct HLA‐DR epitopes and distinct families of HLA‐DR molecules defined by 15 monoclonal antibodies (mAb) either anti‐DR or allo‐anti‐Ia^k crossreacting with human DR molecule. I. Cross‐inhibition studies of mAb cell surface fixation and differential binding of mAb to detergent‐solubilized HLA molecules immobilized to a solid phase by a first mAb

1983 • 112 citations

Functional analysis of DR17(DR3)-restricted mycobacterial T cell epitopes reveals DR17-binding motif and enables the design of allele-specific competitor peptides.

1992 • 105 citations

Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif.

1992 • 85 citations

Origin, structure and motifs of naturally processed MHC class II ligands

1994 • 84 citations

Systemic lupus erythematosus is associated with increased auto‐antibody titers against calreticulin and Grp94, but calreticulin is not the Ro/SS‐A antigen

1994 • 64 citations

Calreticulin synthetic peptide analogues: anti-peptide antibodies in autoimmune rheumatic diseases

1993 • 43 citations

Self-peptides from four HLA-DR alleles share hydrophobic anchor residues near the NH2-terminal including proline as a stop signal for trimming.

1993 • 39 citations

Identification of an HLA-DQ2 peptide binding motif and HLA-DPw3-bound self-peptide by pool sequencing

1994 • 30 citations

Isolation of an HLA‐A2.1 extracted human minor histocompatibility peptide

1993 • 21 citations