Passage of low density lipoproteins through monolayers of human arterial endothelial cells. Effects of vasoactive substances in an in vitro model.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

STUDIES ON INFLAMMATION

1961 • 1,539 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

Hyperlipidemia and Atherosclerosis

1976 • 746 citations

An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.

1979 • 727 citations

Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.

1978 • 621 citations

Visualization of the binding, endocytosis, and transcytosis of low-density lipoprotein in the arterial endothelium in situ.

1983 • 349 citations

Lipoproteins and atherosclerosis. A look back and a look ahead.

1983 • 315 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

Regulation of epithelial tight junction permeability by cyclic AMP

1981 • 296 citations

Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers.

1986 • 289 citations

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells.

1987 • 281 citations

Changes in cytosolic Ca2+ associated with von Willebrand factor release in human endothelial cells exposed to histamine. Study of microcarrier cell monolayers using the fluorescent probe indo-1.

1987 • 225 citations

Thrombin-stimulated elevation of human endothelial-cell cytoplasmic free calcium concentration causes prostacyclin production

1988 • 190 citations

Permeability characteristics of cultured endothelial cell monolayers

1988 • 185 citations

Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin.

1982 • 182 citations

Increased free calcium in endothelial cells under stimulation with adenine nucleotides

1986 • 171 citations

Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers.

1984 • 163 citations

Effects of histamine and some other substances on molecular selectivity of the capillary wall to plasma proteins and dextran

1974 • 114 citations

Increased permeability of microcarrier-cultured endothelial monolayers in response to histamine and thrombin. A model for the in vitro study of increased vasopermeability.

1986 • 113 citations

Role of the low density lipoprotein receptor in penetration of low density lipoprotein into rabbit aortic wall.

1985 • 100 citations

Tight junctions. Their structure, composition, and function.

1984 • 96 citations

Production of plasminogen activators and inhibitor by serially propagated endothelial cells from adult human blood vessels.

1987 • 96 citations

Determinants of capillary permeability: a review of mechanisms based on single capillary studies in the frog.

1986 • 95 citations

Metabolic activity of cholesteryl esters in aortic smooth muscle cells is altered by prostaglandins I2 and E2.

1983 • 94 citations

Local variation in arterial wall permeability to low density lipoprotein in normal rabbit aorta.

1986 • 88 citations

A radioautographic study of the transport of 125I-labeled serum lipoproteins in rat aorta

1973 • 88 citations

ENDOTHELIAL PERMEABILITY: PATHWAYS AND MODULATIONS*

1982 • 69 citations

Serotonin, norepinephrine, and histamine mediation of endothelial cell barrier function in vitro

1986 • 69 citations

Effect of monocyte migration on low density lipoprotein transport across aortic endothelial cell monolayers.

1984 • 65 citations

Effects of moderate hypercholesterolemia on rabbit endothelium.

1981 • 64 citations

Morphological alterations in endothelial cells from human aorta and umbilical vein induced by forskolin and phorbol 12-myristate 13-acetate: a synergistic action of adenylate cyclase and protein kinase C activators.

1986 • 59 citations

Rabbit beta-migrating very low density lipoprotein increases endothelial macromolecular transport without altering electrical resistance.

1986 • 58 citations

Flux of plasma lipoproteins into human arterial intima Comparison between grossly normal and atheromatous intima

1981 • 57 citations

Characterization of an In Vitro Model to Study the Permeability of Human Arterial Endothelial Cell Monolayers

1988 • 57 citations

Action of the stable prostacyclin analogue iloprost on microvascular tone and -permeability in the hamster cheek pouch

1987 • 54 citations

Arterial influx of esterified cholesterol from two plasma lipoprotein fractions and its hydrolysis in vtvo in hype rcholesterolemic rabbits

1981 • 46 citations

Importance of molecular charge for the passage of endogenous macromolecules across continuous capillary walls, studied by serum clearance of Lactate Dehydrogenase (LDH) isoenzymes

1983 • 44 citations

Direct evidence for the contractile capacity of endothelial cells

1981 • 43 citations

Transcellular transport of lipoprotein through arterial endothelial cells in monolayer culture.

1986 • 40 citations

Histamine H1-receptor in endothelial and smooth muscle cells of guinea-pig aorta

1988 • 40 citations

Effect of PGI2 on transcellular transport of fluorescein dextran through an arterial endothelial monolayer

1987 • 39 citations

Quantitation of bradykinin-induced microvascular leakage of FITC-Dextran in rat cremaster muscle

1987 • 33 citations

Propagation and morphologic phenotypes of human umbilical cord artery endothelial cells.

1986 • 33 citations

In vivo transfer of cholesterol from plasma into human aortic tissue

1987 • 27 citations

Focal arteriolar insudation. A response of arterioles to chronic nonspecific irritation.

1987 • 23 citations

High-affinity uptake and degradation of acetylated low density lipoprotein by confluent human vascular endothelial cells

1985 • 21 citations

In vivo flux of plasma cholesterol into human abdominal aorta with advanced atherosclerosis.

1986 • 15 citations

In vivo transfer of cholesterol from plasma into human aortic tissue

1987 • 8 citations

Effect of Cyclandelate on Prostacyclin Release and Cytosolic Free Calcium Concentrations in Human Endothelial Cells

1987 • 2 citations