Metabolic activity of cholesteryl esters in aortic smooth muscle cells is altered by prostaglandins I2 and E2.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Statistical principles in experimental design.

1962 • 27,228 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides

1969 • 774 citations

LYSOSOMES OF THE ARTERIAL WALL

1972 • 410 citations

The generation of prostacyclin by arteries and by the coronary vascular bed is reduced in experimental atherosclerosis in rabbits

1977 • 287 citations

Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits

1978 • 256 citations

Nitroglycerin Stimulates Synthesis of Prostacyclin by Cultured Human Endothelial Cells

1981 • 252 citations

Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP

1978 • 246 citations

Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat.

1977 • 207 citations

Prostaglandins, cyclic nucleotides and cell function

1974 • 180 citations

Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells.

1982 • 170 citations

Regulation of the diurnal rhythm of rat liver β-hydroxy-β-methylglutaryl coenzyme A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone

1974 • 166 citations

Regulation of cellular sterol flux and synthesis by human serum lipoproteins

1974 • 159 citations

Regulation of endothelial cell cyclic nucleotide metabolism by prostacyclin.

1981 • 155 citations

Stimulation by insulin of rat liver β-hydroxy-β-methylglutaryl coenzyme A reductase and cholesterol-synthesizing activities

1973 • 131 citations

Arterial Composition and Metabolism: Esterified Fatty Acids and Cholesterol1 1Publication No. 413 from the Oregon Regional Primate Research Center, supported in part by Grant No. FR 00163 of the National Institutes of Health. The experiments carried out in our laboratory were supported by a grant-in-aid from the National Institutes of Health (HE 09744), Bethesda, Maryland.

1970 • 97 citations

Arterial neutral cholesteryl esterase. A hormone-sensitive enzyme distinct from lysosomal cholesteryl esterase.

1983 • 96 citations

Activation of Cholesteryl Esterase in Bovine Adrenal Cortex

1974 • 92 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. I. Resolution of aortic cell populations by metrizamide density gradient centrifugation.

1977 • 82 citations

Endothelium modifies the altered metabolism of the injured aortic wall.

1981 • 78 citations

Cyclic Nucleotides in Platelet Function

1978 • 68 citations

ACTH-induced hydrolysis of cholesteryl esters in rat adrenal cells.

1978 • 67 citations

Micellar-solubilized substrates and cholesterol esterase activity in vitro

1964 • 57 citations

Separation of six lipid classes on one thin-layer chromatogram

1974 • 57 citations

The effect of glucagon, norepinephrine, and dibutyryl cyclic AMP on cholesterol efflux and on the activity of 3-hydroxy-3-methylglutaryl CoA reductase in rat hepatocytes.

1979 • 54 citations

Effects of PGI2 and PGI analogues on cAMP levels in cultured endothelial and smooth muscle cells derived from bovine arteries

1980 • 52 citations

CHANGES OF CYCLIC‐AMP AND CYCLIC‐AMP PHOSPHODIESTERASE IN THE PROGRESSION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS

1976 • 47 citations

Dibutyryl cyclic AMP decreases proliferative activity and the cholesteryl ester content in cultured cells of atherosclerotic human aorta

1982 • 45 citations

Decreased prostaglandin production in cultured smooth muscle cells from atherosclerotic rabbit aorta

1982 • 43 citations

Activation of adrenal Sterol Ester Hydrolase by dibutyryl cAMP and protein kinase

1974 • 35 citations

Prostaglandin E2 biosynthesis: changes in rabbit aorta and skin during experimental atherogenesis

1976 • 29 citations

Is the variation in the susceptibility of various species to atherosclerosis due to inborn differences in prostacyclin (PGI2) formation?

1980 • 27 citations

Effect of prostaglandins E1 and F1α on the activities of cholesteryl ester synthetase and cholesteryl ester hydrolases of pigeon aorta in vitro

1977 • 27 citations

Prostaglandin E2 biosynthesis and effect in pigeon aorta possible role in atherogenesis

1978 • 25 citations

Prostaglandin E2-induced hydrolysis of cholesterol esters in rat adrenocortical cells

1978 • 25 citations

Inhibition of cholesterol esterification in rabbit aorta by prostaglandin E2

1977 • 25 citations

Regulation of lysosomal enzyme release by prostaglandins, autonomic neurohormones and cyclic nucleotides.

1975 • 25 citations

Cyclic Nucleotides and Atherosclerosis

1980 • 18 citations

Role of cyclic AMP in the actions of luteinizing hormone on steroidogenesis in the corpus luteum.

1978 • 15 citations

Prostaglandin I2 synthesis and elevation of cyclic AMP levels in 3T3 fibroblasts

1980 • 15 citations

Regulation of lysosomal enzyme release by prostaglandins, autonomic neurohormones and cyclic nucleotides.

1975 • 12 citations

EFFECTS OF PROSTAGLANDINS ON THE METABOLISM OF CHOLESTERYL ESTER IN RAT TESTES: CHANGES IN THE SYNTHESIS AND HYDROLYSIS OF CHOLESTERYL ESTER AND THE ACTIVITY OF CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME

1978 • 10 citations