Tight junctions. Their structure, composition, and function.

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Lipid polymorphism and the functional roles of lipids in biological membranes

1979 • 1,817 citations

Structure and Function of Intercellular Junctions

1974 • 1,339 citations

FRACTURE FACES OF ZONULAE OCCLUDENTES FROM "TIGHT" AND "LEAKY" EPITHELIA

1973 • 1,086 citations

CELL JUNCTIONS IN AMPHIBIAN SKIN

1965 • 1,001 citations

Cation Selective Glass Electrodes and their Mode of Operation

1962 • 844 citations

Route of Passive Ion Permeation in Epithelia

1972 • 762 citations

Biological Membranes: The Physical Basis of Ion and Nonelectrolyte Selectivity

1969 • 686 citations

A FINE STRUCTURAL ANALYSIS OF INTERCELLULAR JUNCTIONS IN THE MOUSE LIVER

1970 • 626 citations

α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells

1975 • 599 citations

Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula Occludens

1978 • 569 citations

Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell.

1984 • 506 citations

Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature.

1975 • 430 citations

Lipidic intramembranous particles

1984 • 416 citations

Experimental modulation of occluding junctions in a cultured transporting epithelium.

1980 • 375 citations

Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane?

1981 • 350 citations

Occluding junctions and cytoskeletal components in a cultured transporting epithelium

1980 • 327 citations

Ion fluxes across the pulmonary epithelium and the secretion of lung liquid in the foetal lamb

1974 • 323 citations

Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins.

1976 • 311 citations

The surface epithelium of teleostean fish gills. Cellular and junctional adaptations of the chloride cell in relation to salt adaptation.

1979 • 305 citations

Regulation of epithelial tight junction permeability by cyclic AMP

1981 • 296 citations

Influence of collagen gel on the orientation of epithelial cell polarity: follicle formation from isolated thyroid cells and from preformed monolayers.

1981 • 296 citations

Evidence for the lipidic nature of tight junction strands

1982 • 277 citations

CELL CONTACTS IN THE MOUSE MAMMARY GLAND

1973 • 258 citations

Structure of tight junctions in epithelia with different permeability.

1975 • 247 citations

Freeze-etch appearance of the tight junctions in the epithelium of small and large intestine of mice

1969 • 243 citations

THE ULTRASTRUCTURAL BASIS OF ALVEOLAR-CAPILLARY MEMBRANE PERMEABILITY TO PEROXIDASE USED AS A TRACER

1968 • 227 citations

Redistribution of surface macromolecules in dissociated epithelial cells.

1976 • 202 citations

THE STRUCTURE OF THE ZONULA OCCLUDENS

1974 • 201 citations

PERMEABLE JUNCTIONAL COMPLEXES

1972 • 201 citations

Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs.

1978 • 197 citations

In vivo assembly of tight junctions in fetal rat liver.

1975 • 190 citations

Cell junctions in the early chick embryo—A freeze etch study

1973 • 189 citations

Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins

1980 • 182 citations

Increases in guinea pig small intestinal transepithelial resistance induced by osmotic loads are accompanied by rapid alterations in absorptive-cell tight-junction structure.

1983 • 163 citations

Lack of correlation between tight junction morphology and permeability properties in developing choroid plexus

1976 • 162 citations

Active chloride secretion by rabbit colon: Calcium-dependent stimulation by ionophore A23187

1977 • 160 citations

Assembly of enveloped viruses in Madin-Darby canine kidney cells: polarized budding from single attached cells and from clusters of cells in suspension.

1983 • 151 citations

Viruses budding from either the apical or the basolateral plasma membrane domain of MDCK cells have unique phospholipid compositions.

1982 • 150 citations

Na+-dependent sugar transport in a cultured epithelial cell line from pig kidney

1980 • 149 citations

Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization.

1984 • 139 citations

THE INFLUENCE OF INTRAVASCULAR FLUID VOLUME ON THE PERMEABILITY OF NEWBORN AND ADULT MOUSE LUNGS TO ULTRASTRUCTURAL PROTEIN TRACERS

1971 • 138 citations

Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1). The basolateral systems.

1982 • 137 citations

Transport Pathways in Biological Membranes

1974 • 132 citations

Basolateral plasma membrane localization of ouabain-sensitive sodium transport sites in the secretory epithelium of the avian salt gland

1977 • 125 citations

Opening of tight junctions in frog skin by hypertonic urea solutions

1972 • 121 citations

Ca2+ regulation of tight-junction permeability and structure in Necturus gallbladder

1983 • 118 citations

Tight junctions in the choroid plexus epithelium. A freeze-fracture study including complementary replicas.

1979 • 118 citations

alpha-Actinin localization in the junctional complex of intestinal epithelial cells.

1979 • 116 citations

Epithelial solute permeability, ion transport and tight junction morphology in the developing lung of the fetal lamb

1981 • 115 citations

Effects of glutaraldehyde fixation on the structure of tight junctions. A quantitative freeze-fracture analysis

1979 • 107 citations

Target Cell Polarity and Membrane Phosphorylation in Relation to the Mechanism of Action of Antidiuretic Hormone

1974 • 107 citations

Participation of plasma membrane proteins in the formation of tight junction by cultured epithelial cells

1983 • 102 citations

A hydrophobic form of the small-intestinal sucrase-isomaltase complex

1975 • 102 citations

Do ‘lipidic particles’ represent intermembrane attachment sites?

1980 • 97 citations

Occluding junctions in a cultured transporting epithelium: Structural and functional heterogeneity

1980 • 96 citations

Rapid Massive Assembly of Tight Junction Strands

1981 • 96 citations

Distribution of parathyroid hormone-stimulated adenylate cyclase in plasma membranes of cells of the kidney cortex

1975 • 90 citations

High molecular-weight heparan sulfate from the cell surface

1974 • 90 citations

Alkaline phosphatase and gamma-glutamyl transpeptidase as polarization markers during the organization of LLC-PK1 cells into an epithelial membrane.

1984 • 89 citations

Development of intercellular junctions in the pulmonary epithelium of the foetal lamb

1978 • 89 citations

?-Hydroxysterol distribution as determined by freeze-fracture cytochemistry

1981 • 84 citations

Structure and permeability of goblet cell tight junctions in rat small intestine

1982 • 78 citations

Junction formation in trypsinized cells of human adenocarcinoma cell line

1978 • 58 citations

Junctional complexes of the tubular cells in the human kidney as revealed with freeze-fracture

1975 • 55 citations

Heterogeneity of tight junction morphology in extrapulmonary and intrapulmonary airways of the rat

1980 • 54 citations

The binding of phloridzin to the isolated luminal membrane of the renal proximal tubule

1974 • 52 citations

Functional Properties of the Paracellular Pathway in Some Leaky Epithelia

1983 • 47 citations

Morphogenesis of tight junctions in the peritoneal mesothelium of the mouse embryo

1979 • 42 citations

The Structure of Tight Junctions

1978 • 38 citations

Occluding Junctions and Paracellular Pathways Studied in Monolayers of Mdck Cells

1983 • 36 citations

[3H]ouabain binding during the monolayer organization and cell cycle in MDCK cells

1980 • 35 citations

The occurrence and distribution of H-2 antigens on mouse intestinal epithelial cells.

1979 • 33 citations

The paracellular pathway in toad urinary bladder: Permselectivity and kinetics of opening

1978 • 30 citations

Carbon tetrachloride induced proliferation of tight junctions in the rat liver as revealed by freeze-fracturing.

1979 • 27 citations

Structure of occluding junctions in ileal epithelial cells of suckling rats

1978 • 21 citations

Intramembrane events accompanying junction formation in a liver cell line

1980 • 16 citations