Heme Oxygenase-1 Mediated Cytoprotection Against Liver Ischemia and Reperfusion Injury: Inhibition of Type-1 Interferon Signaling

Toll-like receptors: critical proteins linking innate and acquired immunity

2001 • 4,673 citations

TLR signaling pathways

2004 • 2,359 citations

NEUTROPHIL INFILTRATION AS AN IMPORTANT FACTOR IN LIVER ISCHEMIA AND REPERFUSION INJURY

1993 • 799 citations

Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice

2004 • 603 citations

Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

1999 • 489 citations

Cutting Edge: TLR4 Activation Mediates Liver Ischemia/Reperfusion Inflammatory Response via IFN Regulatory Factor 3-Dependent MyD88-Independent Pathway

2004 • 442 citations

In Vivo Expression of Toll-Like Receptor 2 and 4 by Renal Epithelial Cells: IFN-γ and TNF-α Mediated Up-Regulation During Inflammation

2002 • 431 citations

Hepatic ischemia reperfusion injury: Pathogenic mechanisms and basis for hepatoprotection

2003 • 430 citations

Hepatic ischemia/reperfusion injury—a fresh look

2003 • 407 citations

Hepatic Ischemia/Reperfusion Injury Involves Functional TLR4 Signaling in Nonparenchymal Cells

2005 • 356 citations

Heme oxygenase-1 system in organ transplantation1

2002 • 199 citations

Carbon Monoxide Differentially Modulates STAT1 and STAT3 and Inhibits Apoptosis via a Phosphatidylinositol 3-Kinase/Akt and p38 Kinase-dependent STAT3 Pathway during Anoxia-Reoxygenation Injury

2004 • 196 citations

Role of adapters in Toll-like receptor signalling

2003 • 191 citations

Heme Oxygenase-1 Overexpression Protects Rat Livers from Ischemia/Reperfusion Injury with Extended Cold Preservation

2001 • 178 citations

Endothelial Responses to Oxidized Lipoproteins Determine Genetic Susceptibility to Atherosclerosis in Mice

2000 • 175 citations

Protection from ischemic liver injury by activation of A_2Aadenosine receptors during reperfusion: inhibition of chemokine induction

2004 • 174 citations

Toll‐Like Receptor and Heme Oxygenase‐1 Signaling in Hepatic Ischemia/Reperfusion Injury

2005 • 173 citations

Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury1

2002 • 153 citations

Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases

2003 • 147 citations

CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection

2002 • 122 citations

Toll-like Receptors 2 and 4 Activate STAT1 Serine Phosphorylation by Distinct Mechanisms in Macrophages

2003 • 109 citations

Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection

2003 • 109 citations

Current status of ischemia and reperfusion injury in the liver

2000 • 107 citations

Role of STAT‐1 and STAT‐3 in ischaemia/reperfusion injury

2004 • 105 citations

Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice.

2004 • 97 citations

The Role of Toll-like Receptors in Solid Organ Transplantation

2006 • 74 citations

Redox-regulated mechanisms of IL-4-induced MCP-1 expression in human vascular endothelial cells

2003 • 72 citations

LIVER-INFILTRATING T LYMPHOCYTES ARE ATTRACTED SELECTIVELY BY IFN-INDUCIBLE PROTEIN-10

2000 • 67 citations

Expression of Heme Oxygenase‐1 in Human Livers Before Transplantation Correlates with Graft Injury and Function After Transplantation

2005 • 66 citations

TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-β-dependent signaling in TLR4-mediated responses

2003 • 40 citations

Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: The role of heme oxygenase-1

2003 • 39 citations

The ratio of ELR+ to ELR? CXC chemokines affects the lung and liver injury following hepatic ischemia/reperfusion in the rat

2000 • 39 citations

Hypoxia/re-oxygenation-induced, redox-dependent activation of STAT1 (signal transducer and activator of transcription 1) confers resistance to apoptotic cell death via hsp70 induction

2004 • 36 citations

TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-β-dependent signaling in TLR4-mediated responses

2003 • 32 citations

Interleukin 13 Gene Transfer in Liver Ischemia and Reperfusion Injury: Role of Stat6 and TLR4 Pathways in Cytoprotection

2004 • 29 citations

Induction of specific stress response increases resistance of rat liver allografts to cold ischemia and reperfusion injury

2003 • 18 citations

Induction of specific stress response increases resistance of rat liver allografts to cold ischemia and reperfusion injury

2003 • 17 citations

Induction of heme oxygenase-1 and dilatation of hepatic sinusoids by an administration of pyrrolidine dithiocarbamate in rat livers1

2003 • 13 citations