Rapsyn carboxyl terminal domains mediate muscle specific kinase–induced phosphorylation of the muscle acetylcholine receptor

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

2001 • 1,003 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

An adaptive coding model of neural function in prefrontal cortex

2001 • 744 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse

2001 • 519 citations

Patterning of Muscle Acetylcholine Receptor Gene Expression in the Absence of Motor Innervation

2001 • 463 citations

Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost

2005 • 281 citations

Agrin induces phosphorylation of the nicotinic acetylcholine receptor

1991 • 253 citations

Rapsyn Is Required for MuSK Signaling and Recruits Synaptic Components to a MuSK-Containing Scaffold

1997 • 243 citations

The postsynaptic 43k protein clusters muscle nicotinic acetylcholine receptors in xenopus oocytes

1990 • 237 citations

Neurotransmitter Acetylcholine Negatively Regulates Neuromuscular Synapse Formation by a Cdk5-Dependent Mechanism

2005 • 220 citations

Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter

2005 • 213 citations

ACh Receptor-Rich Membrane Domains Organized in Fibroblasts by Recombinant 43-Kilodalton Protein

1991 • 202 citations

The submembrane machinery for nicotinic acetylcholine receptor clustering.

1991 • 176 citations

Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation.

1996 • 151 citations

Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction

2003 • 133 citations

Building the vertebrate neuromuscular synapse

2002 • 127 citations

Role of Rapsyn Tetratricopeptide Repeat and Coiled-coil Domains in Self-association and Nicotinic Acetylcholine Receptor Clustering

2001 • 122 citations

Src-Class Kinases Act within the Agrin/MuSK Pathway to Regulate Acetylcholine Receptor Phosphorylation, Cytoskeletal Anchoring, and Clustering

2001 • 115 citations

Agrin-Induced Phosphorylation of the Acetylcholine Receptor Regulates Cytoskeletal Anchoring and Clustering

2001 • 113 citations

Rapsyn Clusters and Activates the Synapse-Specific Receptor Tyrosine Kinase MuSK

1996 • 110 citations

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle

1997 • 110 citations

Clustering and immobilization of acetylcholine receptors by the 43-kD protein: a possible role for dystrophin-related protein.

1993 • 107 citations

Interactions of the Rapsyn RING-H2 Domain with Dystroglycan

2001 • 104 citations

Agrin Regulates Rapsyn Interaction with Surface Acetylcholine Receptors, and This Underlies Cytoskeletal Anchoring and Clustering

2003 • 104 citations

Src, Fyn, and Yes Are Not Required for Neuromuscular Synapse Formation But Are Necessary for Stabilization of Agrin-Induced Clusters of Acetylcholine Receptors

2001 • 101 citations

Roles of Rapsyn and Agrin in Interaction of Postsynaptic Proteins with Acetylcholine Receptors

1999 • 95 citations

Functional Interaction of Src Family Kinases with the Acetylcholine Receptor in C2 Myotubes

1996 • 94 citations

Agrin-induced Activation of Acetylcholine Receptor-bound Src Family Kinases Requires Rapsyn and Correlates with Acetylcholine Receptor Clustering

2001 • 85 citations

Binding of the nicotinic acetylcholine receptor to SH2 domains of Fyn and Fyk protein tyrosine kinases.

1994 • 71 citations

Determination of the tyrosine phosphorylation sites of the nicotinic acetylcholine receptor.

1991 • 70 citations

Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation.

1995 • 69 citations

Molecular cloning of two abundant protein tyrosine kinases in Torpedo electric organ that associate with the acetylcholine receptor.

1993 • 61 citations

Phosphorylation and Cytoskeletal Anchoring of the Acetylcholine Receptor by Src Class Protein-tyrosine Kinases

1999 • 52 citations

Acetylcholine receptors are required for agrin-induced clustering of postsynaptic proteins

2001 • 52 citations

A Single Pulse of Agrin Triggers a Pathway That Acts To Cluster Acetylcholine Receptors

2004 • 51 citations

Rapsyn and Agrin Slow the Metabolic Degradation of the Acetylcholine Receptor

1997 • 47 citations

Synaptic differentiation is defective in mice lacking acetylcholine receptor β-subunit tyrosine phosphorylation

2007 • 46 citations

Clustering of the acetylcholine receptor by the 43-kD protein: involvement of the zinc finger domain.

1993 • 45 citations

Tyrosine Phosphorylation of Nicotinic Acetylcholine Receptor Mediates Grb2 Binding

1997 • 45 citations

Metabolic Stabilization of Muscle Nicotinic Acetylcholine Receptor by Rapsyn

1999 • 43 citations

Epitope mapping of antibodies to acetylcholine receptor .alpha. subunits using peptides synthesized on polypropylene pegs

1991 • 41 citations

The Synapse-Associated Protein Rapsyn Regulates Tyrosine Phosphorylation of Proteins Colocalized at Nicotinic Acetylcholine Receptor Clusters

1996 • 36 citations

Recruitment of a Nicotinic Acetylcholine Receptor Mutant Lacking Cytoplasmic Tyrosine Residues in Its β Subunit into Agrin-Induced Aggregates

1998 • 31 citations

The Zinc Finger Domain of the 43-kDa Receptor-Associated Protein, Rapsyn: Role in Acetylcholine Receptor Clustering

1998 • 23 citations

Overexpression of rapsyn inhibits agrin-induced acetylcholine receptor clustering in muscle cells.

1999 • 22 citations

Characterization of phosphotyrosine containing proteins at the cholinergic synapse

1999 • 12 citations