A Casein Kinase II Phosphorylation Site in the Cytoplasmic Domain of the Cation-dependent Mannose 6-Phosphate Receptor Determines the High Affinity Interaction of the AP-1 Golgi Assembly Proteins with Membranes

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

1992 • 540 citations

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

1993 • 422 citations

A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

1988 • 363 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

Biochemical dissection of AP-1 recruitment onto Golgi membranes.

1993 • 308 citations

Targeting of membrane proteins to endosomes and lysosomes

1994 • 304 citations

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

1989 • 272 citations

Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus.

1988 • 263 citations

ARF: a key regulatory switch in membrane traffic and organelle structure

1994 • 258 citations

Possible pathways for lysosomal enzyme delivery.

1985 • 253 citations

The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

1988 • 244 citations

Arf proteins: the membrane traffic police?

1995 • 241 citations

CLATHRIN AND ASSOCIATED ASSEMBLY AND DISASSEMBLY PROTEINS

1990 • 234 citations

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi.

1992 • 225 citations

Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor.

1988 • 210 citations

A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.

1992 • 205 citations

Localization of the signal for rapid internalization of the bovine cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor to amino acids 24-29 of the cytoplasmic tail.

1991 • 188 citations

Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes.

1987 • 174 citations

Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.

1994 • 145 citations

Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor.

1992 • 144 citations

Mannose 6-Phosphate Receptors and ADP-ribosylation Factors Cooperate for High Affinity Interaction of the AP-1 Golgi Assembly Proteins with Membranes

1996 • 121 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

Binding of AP-1 Golgi adaptors to membranes requires phosphorylated cytoplasmic domains of the mannose 6-phosphate/insulin-like growth factor II receptor.

1993 • 101 citations

Mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor. A consensus casein kinase II site followed by 2 leucines near the carboxyl terminus is important for intracellular targeting of lysosomal enzymes.

1993 • 100 citations

Phosphorylation of the cytoplasmic domain of the bovine cation-independent mannose 6-phosphate receptor. Serines 2421 and 2492 are the targets of a casein kinase II associated to the Golgi-derived HAI adaptor complex.

1990 • 86 citations

Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.

1993 • 85 citations

Quaternary structure of the Mr 46,000 mannose 6-phosphate specific receptor: effect of ligand, pH and receptor concentration on the equilibrium between dimeric and tetrameric receptor forms

1990 • 46 citations

Phosphorylation of the human 46-kDa mannose 6-phosphate receptor in the cytoplasmic domain at serine 56

1993 • 32 citations

Rapid equilibrium between monomeric, dimeric and tetrameric forms of the 46‐kDa mannose 6‐phosphate receptor at 37°C

1990 • 31 citations

Gene and pseudogene of the mouse cation-dependent mannose 6-phosphate receptor. Genomic organization, expression, and chromosomal localization.

1992 • 29 citations