Control of gene expression by steroid hormones

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

A two-step mechanism for the interaction of estradiol with rat uterus.

1968 • 1,013 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Effects of methylation on a synthetic polynucleotide: the B--Z transition in poly(dG-m5dC).poly(dG-m5dC).

1981 • 873 citations

Cloning of the human estrogen receptor cDNA.

1985 • 720 citations

The structure of histone H1 and its location in chromatin

1980 • 696 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

1976 • 556 citations

A mechanism for RNA splicing.

1980 • 553 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

SnRNAs, SnRNPs, and RNA Processing

1982 • 458 citations

DNA methylation and the regulation of globin gene expression

1983 • 451 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

THE PATHWAY OF EUKARYOTIC mRNA FORMATION

1983 • 429 citations

Actively transcribed genes are associated with the nuclear matrix

1983 • 396 citations

The HMG chromosomal proteins

1982 • 385 citations

α-globin-gene switching during the development of chicken embryos: Expression and chromosome structure

1981 • 353 citations

RNA Processing and the Intervening Sequence Problem

1979 • 353 citations

Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes

1981 • 350 citations

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

1981 • 341 citations

Mechanism of action of a yeast RNA ligase in tRNA splicing

1983 • 312 citations

Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin.

1983 • 309 citations

Structure of Transcribing Chromatin

1980 • 281 citations

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

1984 • 278 citations

Identification of Human Glucocorticoid Receptor Complementary DNA Clones by Epitope Selection

1985 • 277 citations

Inhibition of progesterone receptor activation by sodium molybdate

1980 • 257 citations

Chicken oviduct progesterone receptor: Location of specific regions of high-affinity binding in cloned DNA fragments of hormone-responsive genes

1982 • 256 citations

Rat liver nuclear skeleton and ribonucleoprotein complexes containing HnRNA.

1978 • 243 citations

More histone structures

1979 • 238 citations

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

1985 • 232 citations

Activation of the glucocorticoid-receptor complex

1982 • 224 citations

Patterns of histone variant synthesis can distinguish go from G1 cells

1982 • 217 citations

The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor.

1985 • 215 citations

Receptors and Hormone Action

1978 • 204 citations

Direct demonstration of glucocorticoid receptor phosphorylation by intact L-cells.

1983 • 200 citations

Heterogeneity of estrogen binding sites in the cytosol of the rat uterus

1978 • 199 citations

Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promoter region

1982 • 181 citations

Equilibrium: the intracellular distribution of steroid receptors

1979 • 176 citations

Two Binding Sites for Estradiol in Rat Uterine Nuclei: Relationship to Uterotropic Response*

1979 • 169 citations

Activation of globin genes during chicken development

1981 • 164 citations

Heterogeneity of estrogen receptors in the cytosol and nuclear fractions of the rat uterus

1978 • 156 citations

Exchange of histone H1 between segments of chromatin

1981 • 155 citations

DNA sequence preference of the progesterone receptor.

1983 • 150 citations

Purified glucocorticoid receptor-hormone complex from rat liver cytosol binds specifically to cloned mouse mammary tumor virus long terminal repeats in vitro.

1982 • 147 citations

The association of transcriptionally active genes with the nuclear matrix of the chicken oviduct

1983 • 145 citations

Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene.

1982 • 142 citations

Preferential affinity of high molecular weight high mobility group non-histone chromatin proteins for single-stranded DNA.

1979 • 142 citations

Nucleotide sequence requirements for specific initiation of transcription by RNA polymerase I.

1982 • 140 citations

ATP-dependent activation of L cell glucocorticoid receptors to the steroid binding form.

1979 • 140 citations

Active gene sequences are undermethylated.

1981 • 139 citations

Phosphorylation in vivo of chicken oviduct progesterone receptor.

1982 • 138 citations

Binding of glucocorticoid receptors to DNA.

1975 • 133 citations

Effect of androgen on the transcription of rat prostatic binding protein genes

1982 • 127 citations

RNA-dependent release of androgen and other steroidreceptor complexes from DNA.

1980 • 116 citations

Androgen Receptor in Rat Skeletal Muscle:Characterization and Physiological Variations*

1980 • 114 citations

Phosphorylation of hen progesterone receptor by cAMP dependent protein kinase

1981 • 112 citations

A 5′-flanking sequence essential for progesterone regulation of an ovalbumin fusion gene

1983 • 111 citations

Mapping of transcription initiation and termination signals on Xenopus laevis ribosomal DNA.

1982 • 110 citations

Involvement of a low molecular weight component(s) in the mechanism of action of the glucocorticoid receptor

1976 • 110 citations

Partial purification of transcriptionally active nucleosomes from trout testis cells

1978 • 106 citations

Progesterone and dexamethasone antagonism of uterine growth: A role for a second nuclear binding site for estradiol in estrogen action

1981 • 105 citations

Ribonucleoprotein Binding of Steroid-“Receptor” Complexes

1973 • 104 citations

Exchange of histones H1, H2A, and H2B in vivo

1985 • 104 citations

The in vivo methylation of DNA in mouse fibroblasts

1969 • 104 citations

The core proteins of 35 S hnRNP complexes

1985 • 101 citations

Eukaryotic Genes: Their Structure, Activity and Regulation

1984 • 97 citations

Rat liver nuclear skeleton and small molecular weight RNA species.

1978 • 97 citations

Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA

1981 • 96 citations

Secondary structure in heterogeneous nuclear RNA: Involvement of regions from repeated DNA sites

1974 • 95 citations

Phosphorylation of rat liver glucocorticoid receptor.

1985 • 94 citations

Regulation of the Androgen and Glucocorticoid Receptors in Rat and Mouse Skeletal Muscle Cytosol*

1981 • 93 citations

Effects of RNA and ribonuclease on the binding of estrogen and glucocorticoid receptors from MCF-7 cells to DNA-cellulose.

1982 • 93 citations

Estrogen-binding proteins of male rat liver: Influences of hormonal changes

1980 • 90 citations

Presence of a DNA demethylating activity in the nucleus of murine erythroleukemic cells.

1982 • 88 citations

Mouse DNA methylase: Methylation of native DNA

1979 • 86 citations

Nucleosome Reconstruction via Phosphorus Mapping

1984 • 85 citations

Estrogen withdrawal in chick oviduct. Selective loss of high abundance classes of polyadenylated messenger RNA

1977 • 84 citations

Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells

1982 • 83 citations

The higher order structure of chromatin and histone H1

1984 • 81 citations

Replication and Transcription Depend on Attachment of DNA to the Nuclear Cage

1984 • 79 citations

Nuclear estrogen receptors. Effect of inhibitors on processing and steady state levels.

1980 • 78 citations

Mechanism of Activation of Steroid Receptors: Involvement of Low Molecular Weight Inhibitor in Activation of Androgen, Glucocorticoid, and Estrogen Receptor Systems*

1980 • 75 citations

The Effects of Ribonuclease on Rat Liver Dexamethasone Receptor: Increased Affinity for Deoxyribonucleic Acid and Altered Sedimentation Profile*

1983 • 75 citations

An Unusual Sex Steroid-Binding Protein in Mature Male Rat Liver Cytosol*

1978 • 75 citations

Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis

1979 • 75 citations

RNA inhibits estrogen receptor binding to DNA.

1981 • 73 citations

Methylated and unmethylated ribosomal RNA genes in the mouse

1981 • 71 citations

Pyridoxine deficiency influences the behavior of the glucocorticoid . receptor complex.

1980 • 65 citations

A conserved histone variant enriched in nucleoli of mammalian cells

1982 • 64 citations

Characteristics of an endogenous glucocorticoid receptor stabilizing factor.

1982 • 62 citations

Nuclear Binding of Estrogen-Receptor Complex: Receptor-Specific Nuclear Acceptor Sites*

1982 • 52 citations

Estrogen Modulation of Nuclear Matrix-Associated Steroid Hormone Binding*

1984 • 50 citations

Ribonucleoprotein organization of eukaryotic RNA

1985 • 48 citations

Involvement of protein HMG1 in DNA replication

1984 • 48 citations

Inactivation of chick oviduct progesterone receptors

1980 • 48 citations

Association of the glucocorticoid hormone receptor with ribonucleic acid

1985 • 47 citations

Addition of poly(A) to nuclear RNA occurs soon after RNA synthesis.

1980 • 46 citations

Poly(A) polymerase and poly(A)-specific mRNA binding protein are antigenically related

1979 • 45 citations

Heterogeneity of Glucocorticoid Binders: A Unique and a Classical Dexamethasone-Binding Site in Bovine Tissues*

1979 • 44 citations

A close association between sites of DNase I hypersensitivity and sites of enhanced cleavage by micrococcal nuclease in the 5′-flanking region of the actively transcribed ovalbumin gene.

1984 • 43 citations

Reconstitution of nativelike nuclear acceptor sites of the avian oviduct progesterone receptor: evidence for involvement of specific chromatin proteins and specific DNA sequences

1984 • 39 citations

Nucleocytoplasmic RNA transport

1985 • 37 citations

Newly Formed mRNA Lacking Polyadenylic Acid Enters the Cytoplasm and the Polyribosomes but Has a Shorter Half-Life in the Absence of Polyadenylic Acid

1982 • 35 citations

The nuclear binding of estradiol stimulates ribonucleoprotein transport in the rat uterus.

1985 • 35 citations

A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences

1981 • 35 citations

Binding of estradiol to purified uterine plasma membranes.

1979 • 34 citations

Lampbrush chromosomes

1987 • 34 citations

DNA sequences involved in the regulation of gene expression by glucocorticoid hormones

1984 • 33 citations

Differences in rearrangements of H1 and H5 in chicken erythrocyte chromatin

1981 • 33 citations

Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins.

1977 • 33 citations

A Novel Nuclear Form of Estradiol Receptor in MCF-7 Human Breast Cancer Cells

1984 • 32 citations

The nuclear matrix continues DNA synthesis at in vivo replicational forks

1985 • 32 citations

Enrichment of acetylated histones in polynucleosomes containing high mobility group protein 17 revealed by immunoaffinity chromatography.

1984 • 31 citations

Molecular Structure and Analysis of Progesterone Receptors

1978 • 31 citations

Effects of ovariectomy and estradiol injection on nuclear structures of endometrial epithelial cells

1978 • 31 citations

Immunolocalization and Structural Organization of Nascent RNP

1981 • 31 citations

Assessment of estrogen receptor--histone interactions.

1981 • 29 citations

Effects of Estradiol on the Acetylation of Histones in the Fetal Uterus of the Guinea Pig

1981 • 28 citations

Inactivation, Activation, and Stabilization of Glucocorticoid Receptors

1984 • 27 citations

A novel oestrogen-binding species in rat granulosa cells

1984 • 27 citations

Chromatin freeze fracture electron microscopy: a comparative study of core particles, chromatin, metaphase chromosomes, and nuclei

1980 • 27 citations

Partial purification and properties of a pre-mRNA splicing activity.

1985 • 27 citations

The status of small nuclear RNA in the ribonucleoprotein fibrils containing heterogeneous nuclear RNA

1981 • 26 citations

Role in Gene Structure and Function

1982 • 26 citations

STUDIES ON ANDROGEN TRANSPORT INTO CANINE PROSTATE IN VITRO

1976 • 24 citations

Binding of the estradiol-receptor complex to reconstituted nucleoacidic protein from calf uterus

1984 • 24 citations

Identification of a novel sex steroid binding protein.

1982 • 24 citations

Morphology of transcriptional units at different states of activity

1978 • 22 citations

Estrogen receptor in the mammalian liver.

1979 • 21 citations

Effects of highly purified estrogen receptors on gene transcription in isolated nuclei

1982 • 21 citations

Evidence for specific DNA sequences in the nuclear acceptor sites of the avian oviduct progesterone receptor.

1985 • 18 citations

The Unusual Estrogen-Binding Protein (UEBP) of male rat liver: Structural determinants of ligands

1983 • 16 citations

Enzymatic histone modification during the induction of tyrosine aminotransferase with insulin and hydrocortisone

1973 • 15 citations

Interactions of nuclear estrogen receptor with DNA and RNA

1983 • 15 citations

Regulation of the peptide elongation reaction on uterine ribosomes by estrogens

1982 • 14 citations

Nuclear Localization of Unoccupied Oestrogen Receptors

1984 • 14 citations

Small RNAs in HnRNP fibrils and their possible function in splicing

1981 • 14 citations

Evidence that pH induced activation of the rat hepatic glucocorticoid-receptor complex is irreversible

1984 • 13 citations

Further characterization of the second oestrogen-binding species of the rat granulosa cell

1984 • 9 citations

Oestrogen specific binding sites in bovine muscle nuclei

1986 • 8 citations

Heterogeneity and distribution of estrogen binding sites in guinea pig seminal vesicle

1984 • 7 citations

Nucleocytoplasmic Transport of Ribosomal Subparticles: Interplay with the Nuclear Envelope

1981 • 7 citations

A novel class of inactive steroid-binding sites in female rat liver nuclei

1986 • 6 citations

Postsynthetic Modifications

1982 • 5 citations

Location of endogenous RNA polymerase B in a sub‐fraction of rat liver chromatin

1976 • 4 citations

Low-Molecular-Weight Nuclear Ribonucleoprotein Particles

1981 • 3 citations

The structure and function of the progesterone receptor

1981 • 3 citations

83 Liver nuclear steroid receptors, affinities and anabolic agent competition

1983 • 1 citations