Immunolocalization and Structural Organization of Nascent RNP

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Structure of Chromatin

1977 • 1,276 citations

Solenoidal model for superstructure in chromatin.

1976 • 1,223 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

The structure of histone-depleted metaphase chromosomes

1977 • 1,083 citations

Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA

1978 • 763 citations

Gene Activity in Early Development

1976 • 655 citations

Fine structural organization of the interphase nucleus in some mammalian cells

1969 • 632 citations

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

1976 • 556 citations

Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.

1976 • 523 citations

Small molecular weight monodisperse nuclear RNA

1968 • 500 citations

Structural organization of nuclear complexes containing DNA-like RNA

1968 • 457 citations

Identification and characterization of the packaging proteins of core 40S hnRNP particles

1977 • 451 citations

Ultrastructural patterns of RNA synthesis during early embryogenesis of Drosophila melanogaster

1976 • 409 citations

The expression of three abundance classes of messenger RNA in mouse tissues

1976 • 401 citations

General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus

1973 • 389 citations

The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity

1979 • 389 citations

MORPHOLOGICAL STUDIES OF TRANSCRIPTION

1972 • 378 citations

Structural and transcriptional features of the mouse spermatid genome.

1975 • 376 citations

Fluorescent Protein Tracing

1969 • 364 citations

Unequal Crossover and the Evolution of Multigene Families

1974 • 360 citations

Ribonukleins�ure-Synthese der Riesenchromosomen

1964 • 346 citations

Lampbrush chromosomes of crested newtsTriturus cristatus(Laurenti)

1960 • 343 citations

High resolution detection of DNA–RNA hybrids in situ by indirect immunofluorescence

1977 • 305 citations

Structural gene sets active in embryos and adult tissues of the sea urchin

1976 • 298 citations

Proteins associated with heterogeneous nuclear RNA in eukaryotic cells

1974 • 297 citations

Role of nonhistone proteins in metaphase chromosome structure

1977 • 269 citations

H ³ URIDINE INCORPORATION IN LAMPBRUSH CHROMOSOMES

1962 • 259 citations

Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei.

1978 • 245 citations

A model for chromatin based upon two symmetrically paired half-nucleosomes

1976 • 245 citations

Isolation of a 7S particle from Xenopus laevis oocytes: a 5S RNA-protein complex.

1979 • 244 citations

Rat liver nuclear skeleton and ribonucleoprotein complexes containing HnRNA.

1978 • 243 citations

The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

1978 • 242 citations

Localisation of rapidly and slowly labelled nuclear RNA as visualized by high resolution autoradiography

1971 • 233 citations

Comparative aspects of DNA organization in metazoa

1975 • 231 citations

Units of transcription and translation: Sequence components of heterogeneous nuclear RNA and messenger RNA

1975 • 226 citations

Isolation and characterization of the nuclear matrix in friend erythroleukemia cells: Chromatin and hnRNA interactions with the nuclear matrix

1979 • 221 citations

The synthesis and storage of histones during the oogenesis of Xenopus laevis

1977 • 221 citations

Comparative organization of active transcription units in Oncopeltus fasciatus

1976 • 205 citations

Lampbrush chromosomes from oocyte nuclei of the newt

1954 • 205 citations

The submicroscopic structure of the balbiani-ring

1954 • 198 citations

Histone synthesis in early amphibian development: Histone and DNA syntheses are not co-ordinated

1974 • 184 citations

The Nature of Lampbrush Chromosomes

1963 • 184 citations

Localization and characterization of newly synthesized nuclear RNA in isolated rat hepatocytes

1976 • 184 citations

Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA.

1977 • 177 citations

Localization of RNA polymerase in polytene chromosomes of Drosophila melanogaster.

1977 • 175 citations

THE BASE COMPOSITION OF NUCLEIC ACIDS IN CHROMOSOMES, PUFFS, NUCLEOLI, AND CYTOPLASM OF CHIRONOMUS SALIVARY GLAND CELLS

1962 • 175 citations

Transcription Units for mRNA Production in Eukaryotic Cells and Their DNA Viruses

1979 • 173 citations

Sequence complexity of heterogeneous nuclear RNA in sea urchin embryos

1975 • 167 citations

Arrangement of specific oligonucleotides within poly(A) terminated HnRNA molecules

1974 • 166 citations

Factors involved in the expression of gene activity in polytene chromosomes

1968 • 166 citations

Changes of nucleosome frequency in nucleolar and non-nucleolar chromatin as a function of transcription: an electron microscopic study

1978 • 161 citations

A kinetic estimation of base sequence complexity of nuclear poly(A)-containing RNA in mouse friend cells

1975 • 160 citations

Electron Microscopic Analysis of Chromosome Metabolism in the Drosophila melanogaster Embryo

1978 • 154 citations

Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells

1977 • 153 citations

Contractile proteins

1975 • 153 citations

Major nonhistone proteins of rat liver chromatin: preliminary identification of myosin, actin, tubulin, and tropomyosin.

1975 • 151 citations

High-fidelity transcription of 5S DNA injected into Xenopus oocytes.

1977 • 146 citations

Characterization of active transcription units in Balbiani rings of chironomus tentans

1979 • 146 citations

THE RELATIONSHIP BETWEEN RNA SYNTHESIS AND LOOP STRUCTURE IN LAMPBRUSH CHROMOSOMES

1963 • 145 citations

Visualization of RNA Synthesis on Chromosomes

1972 • 141 citations

The chromosome fiber: Evidence for an ordered superstructure of nucleosomes

1977 • 141 citations

Non-coordinated Accumulation and Synthesis of 5S Ribonucleic Acid by Ovaries of Xenopus laevis

1971 • 139 citations

Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells

1975 • 136 citations

Sedimentation properties of the newly synthesized RNA from isolated nuclear components of Chironomus tentans salivary gland cells

1967 • 132 citations

Selective and accurate transcription of the Xenopus laevis 5S RNA genes in isolated chromatin by purified RNA polymerase III.

1977 • 132 citations

Message and non-message sequences adjacent to poly(A) in steady state heterogeneous nuclear RNA of HeLa cells

1976 • 131 citations

Electronmicroscopy of Genetic Activity

1973 • 126 citations

Developmental Studies on Giant Chromosomes

1972 • 125 citations

The association of protein with the polyadenylic acid of HeLa cell messenger RNA: Evidence for a “Transport” role of a 75,000 molecular weight polypeptide

1976 • 118 citations

Transcription of cloned Xenopus ribosomal genes visualised after injection into oocyte nuclei

1978 • 117 citations

Maternal effects on development

1976 • 116 citations

Mechanism for RNA splicing of gene transcripts

1979 • 114 citations

A method for determination of the in situ distribution of chromosomal proteins.

1976 • 112 citations

Recherches biochimiques sur l'oogene`se

1971 • 110 citations

The size of the transcription unit in balbiani ring 2 of Chironomus tentans as derived from analysis of the primary transcript and 75 S RNA

1978 • 107 citations

Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA

1975 • 106 citations

Satellite DNA is transcribed on lampbrush chromosomes

1980 • 106 citations

Transcription of cloned tRNA gene fragments and subfragments injected into the oocyte nucleus of Xenopus laevis.

1978 • 103 citations

Analysis of chromatin-associated fiber arrays

1976 • 103 citations

Morphology of transcription units inDrosophila melanogaster

1976 • 103 citations

Some Properties of RNA:Protein Complexes from the Nucleus of Eukaryotic Cells

1974 • 102 citations

Specific representation of cloned repetitive DNA sequences in sea urchin RNAs

1978 • 101 citations

Nuclear pore flow rate of ribosomal RNA and chain growth rate of its precursor during oogenesis of Xenopus laevis

1973 • 101 citations

Portrait of a gene

1969 • 99 citations

SMALL GRANULES IN THE AMPHIBIAN OOCYTE NUCLEUS AND THEIR RELATIONSHIP TO RNA

1956 • 98 citations

Cloned single repeating units of 5S DNA direct accurate transcription of 5S RNA when injected into Xenopus oocytes.

1978 • 98 citations

Giant RNA Transcript in a Balbiani Ring

1972 • 97 citations

Rat liver nuclear skeleton and small molecular weight RNA species.

1978 • 97 citations

Inhibition of Balbiani ring RNA synthesis at the initiation level.

1975 • 97 citations

Locations of chromosomal proteins in polytene chromosomes.

1976 • 96 citations

Salt-induced structural changes of nucleosome core particles

1979 • 96 citations

Secondary structure in heterogeneous nuclear RNA: Involvement of regions from repeated DNA sites

1974 • 95 citations

Recherches biochimiques sur l'oogene`se: I. Synthe`se et accumulation du RNA pendant l'oogene`se du crapaud sud-africain Xenopus laevis

1971 • 93 citations

A protein that preferentially binds Drosophila satellite DNA.

1979 • 89 citations

The precursor of mouse β-globin messenger RNA contains two intervening RNA sequences

1978 • 89 citations

Differential Metabolism of Large and Small Poly(A) Sequences in the Heterogeneous Nuclear RNA of HeLa Cells

1974 • 85 citations

Transcription of Xenopus tDNAFormula and Sea Urchin Histone DNA Injected into the Xenopus Oocyte Nucleus

1978 • 82 citations

Electron Microscopic Visualization of Transcription

1970 • 82 citations

CHROMOSOMAL DIFFERENTIATIONS OF THE LAMPBRUSH TYPE FORMED BY THE Y CHROMOSOME IN DROSOPHILA HYDEI AND DROSOPHILA NEOHYDEI

1963 • 80 citations

In vitro RNA-RNA splicing in adenovirus 2 mRNA formation.

1978 • 79 citations

D-RNA Containing Ribonucleoprotein Particles

1971 • 79 citations

Identification of the lampbrush chromosome loops which transcribe 5S ribosomal RNA in Notophthalmus (Triturus) viridescens

1975 • 74 citations

Classification of loops of lampbrush chromosomes according to the arrangement of transcriptional complexes

1976 • 74 citations

The structure of chromosome-derived ribonucleoprotein in oocytes of Triturus cristatus carnifex (Laurenti)

1974 • 73 citations

Complexes de transcription d'origines nucl�olaire et chromosomique d'ovocytes de Pleurodeles waltlii et P. poireti (Amphibiens, Urod�les)

1975 • 73 citations

Nuclear labelling after prolonged 3H-uridine incorporation as visualized by high resolution autoradiography

1973 • 72 citations

Morphology of Transcriptionally Active Chromatin

1978 • 72 citations

Ribonuclease-stable base sequences specific exclusively for giant dRNA

1972 • 70 citations

Evidence for a polarized movement of the lateral loops of newt lampbrush chromosomes during oogenesis

1969 • 70 citations

An electron-microscope study of the lampbrush chromosomes of the newt Triturus cristatus

1975 • 68 citations

Nucleoplasmic ribonucleoprotein particles of rat liver. II. Physical properties and action of dissociating agents.

1971 • 67 citations

Structure and Function of the Y Chromosome of Drosophila hydei

1974 • 66 citations

Immunoglobulin light chain mRNA is processed from large nuclear RNA.

1978 • 66 citations

Occurrence of Uridylate-Rich Oligonucleotide Regions in Heterogeneous Nuclear RNA of HeLa Cells

1972 • 64 citations

Localization of histone gene transcripts in newt lampbrush chromosomes by in situ hybridization

1977 • 63 citations

Substructure of Nuclear Ribonucleoprotein Complexes

1978 • 62 citations

Ribonucleoprotein particles derived from the lampbrush chromosomes of newt oocytes

1973 • 59 citations

Nucleosome Structure II: Structure of the SV40 Minichromosome and Electron Microscopic Evidence for Reversible Transitions of the Nucleosome Structure

1978 • 59 citations

Distribution patterns of three subfractions of drosophila nonhistone chromosomal proteins: possible correlations with gene activity

1977 • 58 citations

Population cytogenetics of the genus Caledia (orthoptera: acridinae)

1976 • 56 citations

Injected histone antibodies interfere with transcription of lampbrush chromosome loops in oocytes of Pleurodeles

1979 • 56 citations

Chromatin structure visualization by immunoelectron microscopy

1976 • 56 citations

Nucleoplasmic ribonucleoprotein particles of rat liver

1971 • 55 citations

Nuclear Ribonucleoprotein Complexes Containing Polyadenylate from Mouse Ascites Cells

1974 • 55 citations

A comparative study of the protein components of ribonucleoprotein particles isolated from rat liver and hepatoma nuclei

1973 • 54 citations

Transcription of genetic information in amphibian oocytes

1976 • 52 citations

Visualization of the Silk Fibroin Transcription Unit and Nascent Silk Fibroin Molecules on Polyribosomes of Bombyx mori

1977 • 52 citations

Specific histone-histone contacts are ruptured when nucleosomes unfold at low ionic strength

1979 • 51 citations

Effects of Sodium Chloride and Pancreatic Ribonuclease on the Rat‐Brain Nuclear Particles: The Fate of the Protein Moiety

1974 • 50 citations

Lampbrush-type chromosomes in the primary nucleus of the green alga Acetabularia mediterranea

1975 • 50 citations

Chromosome Puffs and Gene Expression in Polytene Cells

1974 • 49 citations

Immunofluorescent localization of transcriptional activity on lampbrush chromosomes

1978 • 47 citations

The structure of nuclear ribonucleoprotein of amphibian oocytes

1977 • 45 citations

Location of nuclear proteins on the chromosomes of newt oocytes

1974 • 44 citations

Lampbrush chromosomes in spermatocytes of Chironomus

1975 • 43 citations

Immunofluorescent labeling of chromosomes with antisera to histones and histone fractions

1972 • 41 citations

Visualization of two different types of nuclear transcriptional complexes in rat liver cells

1977 • 41 citations

Appearance of rapidly labeled, high molecular weight RNA in nuclear ribonucleoprotein. Release from chromatin and association with protein.

1976 • 41 citations

Detection of mRNA sequences in nuclear 30S ribonucleoprotein subcomplexes.

1976 • 40 citations

The primary ribosomal DNA transcript in eukaryotes

1978 • 40 citations

Identification of a small subfraction of hnRNA with the characteristics of a precursor to mRNA

1974 • 38 citations

Synthese und Abbau der Nucleins�uren w�hrend der Entwicklung des Makronukleus von Stylonychia mytilus (Protozoa, Ciliata)

1968 • 37 citations

The Chromosomal Arrangement of Coding Sequences in a Family of Repeated Genes

1977 • 36 citations

Visualization of gene transcription in spermatocytes of Drosophila hydei

1975 • 35 citations

HnRNP core proteins: Synthesis, turnover and intracellular distribution

1979 • 33 citations

A quantitative electron microscopic analysis of transcription in sea urchin embryos

1979 • 33 citations

Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins.

1977 • 33 citations

Visual Demonstration of Allelic Differences Within Cell Nuclei

1956 • 33 citations

Histone distribution in chromosomes revealed by antihistone sera

1976 • 28 citations

Ultrastructure of Chromatin Subunits during Unfolding, Histone Depletion, and Reconstitution

1978 • 28 citations

Silver staining of the lampbrush chromosomes ofTriturus cristatus carnifex

1978 • 27 citations

Demonstration of Balbiani ring RNA sequences in polysomes.

1977 • 25 citations

Distribution of hnRNA and mRNA Sequences in Nuclear Ribonucleoprotein Complexes

1977 • 25 citations

Gene and information diversity in eukaryotes

1976 • 24 citations

Histone localization in polytene chromosomes by immunofluorescence.

1978 • 23 citations

Purification of a Protein from Unfertilized Eggs of Drosophila with Specific Affinity for a Defined DNA Sequence and the Cloning of This DNA Sequence in Bacterial Plasmids

1978 • 23 citations

A quantitative electron-microscope analysis of chromatin from Xenopus laevis lampbrush chromosomes

1979 • 22 citations

Morphology of transcriptional units at different states of activity

1978 • 22 citations

The actions of restriction endonucleases on lampbrush chromosomes

1976 • 21 citations

Heterogeneity in the interaction of chromatin subunits with anti-histone sera visualized by immuno-electron microscopy

1978 • 21 citations

Immunological Probes for Chromatin Structure

1978 • 18 citations

Visualization of nonribosomal transcriptional complexes after cortisol stimulation of isolated rat liver cells

1978 • 18 citations

Distribution of coding sequences within the nuclear HnRNA—protein complexes

1978 • 17 citations

Digestion of RNA of chromatin and nuclear ribonucleoprotein by staphylococcal nuclease

1976 • 17 citations

In situ hybridization to lampbrush chromosomes: A potential source of error exposed

1980 • 16 citations

Non-nucleolar transcription complexes of rat liver as revealed by spreading isolated nuclei

1979 • 15 citations

A reversible conformational transition in chromatin

1979 • 13 citations

Regular substructures within homologous transcripts of spread germ cells

1980 • 11 citations

Transcription Complexes of Chromatin Showing a Beads-like Structure of Heterogeneous Ribonucleoprotein chains

1977 • 10 citations

The organization of transcription on lampbrush chromosomes

1978 • 9 citations

Visualization of mouse DNA transcriptional complexes in mouse kidney cells infected with SV 40 virus.

1978 • 8 citations

Electron microscope observations of the organisation of chromatin fibers in isolated nuclei of rat liver

1974 • 7 citations

Ultrastructure of Gene Transcription in Spermatocytes of Trichosia pubescens Morgante, 1969 (Diptera: Sciaridae)

1976 • 6 citations

Free Informofers and Reconstitution of 30S RNP

1978 • 5 citations

Inversion heterozygosity in females of the newt No tophthalmus viridescens and its influence on chiasma distribution

1977 • 4 citations

GENE EXPRESSION IN LAMPBRUSH CHROMOSOMES

1979 • 3 citations

IV. Functional Units Molecular architecture of Drosphila chromatin

1978 • 1 citations