Human Insulin-Receptor Gene: Partial Sequence and Amplification of Exons by Polymerase Chain Reaction

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Role of Insulin Resistance in Human Disease

1988 • 12,099 citations

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

1989 • 3,458 citations

The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

1988 • 2,463 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.

1989 • 2,011 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

Structure of the human insulin receptor gene and characterization of its promoter.

1989 • 349 citations

Two Mutant Alleles of the Insulin Receptor Gene in a Patient with Extreme Insulin Resistance

1988 • 308 citations

Insulin-Resistant Diabetes Due to a Point Mutation That Prevents Insulin Proreceptor Processing

1988 • 253 citations

Human Diabetes Associated with a Mutation in the Tyrosine Kinase Domain of the Insulin Receptor

1989 • 192 citations

A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin-resistant diabetes.

1989 • 155 citations

Detection of an Alteration in the Insulin-Receptor Gene in a Patient with Insulin Resistance, Acanthosis Nigricans, and the Polycystic Ovary Syndrome (Type A Insulin Resistance)

1988 • 153 citations

Human Diabetes Associated with a Deletion of the Tyrosine Kinase Domain of the Insulin Receptor

1989 • 129 citations

Familial Hyperinsulinemia Due to a Structurally Abnormal Insulin

1984 • 93 citations

A leucine-to-proline mutation in the insulin receptor in a family with insulin resistance.

1989 • 77 citations

Insulin-Receptor and Apolipoprotein Genes Contribute to Development of NIDDM in Chinese Americans

1989 • 58 citations

Insulin-Receptor Gene and Its Expression in Patients With Insulin Resistance

1989 • 35 citations

Insulin Wakayama: familial mutant insulin syndrome in Japan

1987 • 33 citations

Molecular and Clinical Characterization of an Insertional Polymorphism of the Insulin-Receptor Gene

1989 • 19 citations