Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Pathological Changes Induced in Cerebrocortical Neurons by Phencyclidine and Related Drugs

1989 • 1,235 citations

Stimulus-transcription coupling in neurons: role of cellular immediate-early genes

1989 • 973 citations

Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.

1989 • 484 citations

Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo

1988 • 437 citations

N-methyl-d-aspartate promotes the survival of cerebellar granule cells in culture

1988 • 437 citations

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.

1988 • 384 citations

Noncompetitive excitatory amino acid receptor antagonists

1990 • 361 citations

Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

1987 • 309 citations

Sustained Dendritic Gradients of Ca ²⁺ Induced by Excitatory Amino Acids in CA1 Hippocampal Neurons

1988 • 301 citations

NMDA receptor antagonists disrupt the retinotectal topographic map

1989 • 293 citations

Ischemic Damage in Hippocampal CA1 is Dependent on Glutamate Release and Intact Innervation from CA3

1989 • 249 citations

In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.

1989 • 236 citations

Modulation of Glutamate Receptors: Molecular Mechanisms and Functional Implications

1989 • 198 citations

Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia

1988 • 192 citations

Regulation of synaptic transmission in the central nervous system: Long-term potentiation

1989 • 186 citations

Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.

1990 • 179 citations

Neuronal death in vitro: parallelism between survivability of hippocampal neurones and sustained elevation of cytosolic Ca2+ after exposure to glutamate receptor agonist

1988 • 178 citations

Excitatory amino acid neurotransmission

1988 • 173 citations

Identification of the protein kinase C phosphorylation site in neuromodulin

1990 • 164 citations

Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons

1990 • 155 citations

Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells

1987 • 146 citations

Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids.

1990 • 132 citations

Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture

1988 • 131 citations

Protein kinase C activity in the rat hippocampus after forebrain ischemia: autoradiographic analysis by [3H]phorbol 12,13-dibutyrate

1989 • 116 citations

Neurotransmitter glutamate: its clinical importance

2009 • 113 citations

Cyclic GMP and cell death in rat cerebellar slices

1988 • 92 citations

Ca2+-mediated neuronal death in rat brain neuronal cultures by veratridine: protection by flunarizine.

1989 • 80 citations

Glutamate receptor agonists increase intracellular Ca2+ independently of voltage-gated Ca2+ channels in rat cerebellar granule cells

1989 • 73 citations

Differential accumulation of diacyl and plasmalogenic diglycerides during myocardial ischemia.

1989 • 46 citations

Amiloride blocks glutamate-operated cationic channels and protects neurons in culture from glutamate-induced death

1990 • 35 citations

Ornithine Decarboxylase Activity and Putrescine Levels in Reversible Cerebral Ischemia of Mongolian Gerbils: Effect of Barbiturate

1990 • 25 citations