Effects of Rapid Tryptophan Depletion on Sleep Electroencephalogram and Mood in Subjects with Partially Remitted Depression on Bupropion

A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects

1968 • 11,801 citations

Development of a Rating Scale for Primary Depressive Illness

1967 • 8,216 citations

A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects

1969 • 5,164 citations

Sleep and Psychiatric Disorders

1992 • 1,437 citations

Serotonin Function and the Mechanism of Antidepressant Action

1990 • 911 citations

The determination of tryptophan in plasma, liver, and urine.

1967 • 826 citations

Tryptophan depletion causes a rapid lowering of mood in normal males

1985 • 726 citations

Bupropion: a review of its mechanism of antidepressant activity.

1995 • 693 citations

Paradoxical sleep and its chemical/structural substrates in the brain

1991 • 402 citations

Essential Psychopharmacology: Neuroscientific Basis and Practical Applications

1996 • 374 citations

Mood-Lowering Effect of Tryptophan Depletion

1994 • 339 citations

Mechanism of action of antidepressant medications.

1999 • 307 citations

Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action

1999 • 306 citations

Serotonin and the Neurobiology of Depression

1994 • 286 citations

Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Tryptophan Depletion—Induced Depressive Relapse

1997 • 275 citations

Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5-hydroxyindoleacetic acid by a tryptophan-free diet

1974 • 264 citations

Essential Psychopharmacology: Neuroscientific Basis and Practical Applications

2001 • 251 citations

REM sleep and depression: common neurobiological control mechanisms

1982 • 248 citations

Mood Response to Acute Tryptophan Depletion in Healthy Volunteers: Sex Differences and Temporal Stability

1996 • 243 citations

Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments.

1994 • 241 citations

Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro.

1992 • 224 citations

Clinical and Physiological Consequences of Rapid Tryptophan Depletion

2000 • 206 citations

Chronic antidepressant administration decreases the expression of tyrosine hydroxylase in the rat locus coeruleus.

1990 • 203 citations

Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression.

1991 • 191 citations

Evidence that the Acute Behavioral and Electrophysiological Effects of Bupropion (Wellbutrin®) Are Mediated by a Noradrenergic Mechanism

1994 • 188 citations

Predictors of Mood Response to Acute Tryptophan Depletion A Reanalysis

2002 • 182 citations

Changes During Weeks in Effects of Tricyclic Drugs on the Human Sleeping Brain

1972 • 182 citations

Mechanisms of action and clinical characteristics of three atypical antidepressants: venlafaxine, nefazodone, bupropion

1998 • 176 citations

Serotonin release varies with brain tryptophan levels

1990 • 165 citations

Noradrenaline hyperpolarizes identified rat mesopontine cholinergic neurons in vitro

1993 • 154 citations

Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders

1999 • 141 citations

REM sleep enhancement by bupropion in depressed men

1995 • 114 citations

Effects of chronic bupropion on interstitial concentrations of dopamine in rat nucleus accumbens and striatum.

1992 • 109 citations

Acute tryptophan depletion blocks morphine analgesia in the cold-pressor test in humans

1992 • 104 citations

Decrease in plasma tryptophan after tryptophan-free amino acid mixtures in man

1988 • 89 citations

Effects of a Tryptophan-Free Amino Acid Drink Challenge on Normal Human Sleep Electroencephalogram and Mood

1998 • 83 citations

Antidepressants Reduce Whole-Body Norepinephrine Turnover While Enhancing 6-Hydroxymelatonin Output

1988 • 79 citations

In vivo measurement of 5-hydroxytryptamine turnover rate in the rat brain from the conversion of C14-tryptophan to C14-5-hydroxytryptamine.

1969 • 77 citations

Impact of Experimentally Induced Serotonin Deficiency by Tryptophan Depletion on Sleep EEG in Healthy Subjects

1998 • 77 citations

Psychopharmacology of Antidepressants

1997 • 77 citations

Tryptophan depletion in SSRI-recovered depressed outpatients

2001 • 72 citations

Rapid Tryptophan Depletion, Sleep Electroencephalogram, and Mood in Men With Remitted Depression on Serotonin Reuptake Inhibitors

1998 • 71 citations

Effects of Tryptophan Depletion in Drug-Free Depressed Patients Who Responded to Total Sleep Deprivation

1998 • 67 citations

Sleep Mechanisms: Biology and Control of REM Sleep

1982 • 66 citations

The Effect of Tryptophan Depletion on Mood in Medication-Free, Former Patients with Major Affective Disorder

1997 • 61 citations

The effect of imipramine, desmethylimipramine and chlorpromazine of the sleep-wakefulness cycle of the cat

1965 • 61 citations

Longitudinal Effects of Nortriptyline on EEG Sleep and the Likelihood of Recurrence in Elderly Depressed Patients

1996 • 56 citations

Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder

2001 • 52 citations

Depressive relapse following acute tryptophan depletion in patients with major depressive disorder

2000 • 47 citations

Rapid tryptophan depletion in drug-free depressed patients with seasonal affective disorder

1997 • 46 citations

Acute tryptophan depletion in healthy young women with a family history of major affective disorder

1999 • 45 citations

Maintenance nortriptyline effects on electroencephalographic sleep in elderly patients with recurrent major depression: Double-blind, placebo- and plasma-level-controlled evaluation

1997 • 31 citations

REM sleep inhibition by desipramine: evidence for an α-1 adrenergic mechanism

1995 • 22 citations

EEG Sleep Measures in Later-Life Bereavement Depression: A Randomized, Double-Blind, Placebo-Controlled Evaluation of Nortriptyline

1999 • 20 citations

Relationships between brain concentrations of desipramine and paradoxical sleep inhibition in the rat

1983 • 18 citations

The Acute Effects of the Noradrenaline Reuptake Inhibitor Org 4428 on EEG Sleep in Healthy Volunteers

1999 • 10 citations

The Mood-Lowering Effect of Tryptophan Depletion: Possible Explanation for Discrepant Findings—Reply

2001 • 2 citations

Deleted Work

1955 • 0 citations