A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes

1989 • 1,004 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

DNA REPAIR ENZYMES

1988 • 822 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases

1988 • 602 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21

1988 • 532 citations

Codon preference and its use in identifying protein coding regions in long DNA sequences

1982 • 476 citations

Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence.

1987 • 393 citations

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

1984 • 379 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae

1988 • 361 citations

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

1986 • 351 citations

Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins

1984 • 341 citations

Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene

1986 • 330 citations

Molecular cloning of a human DNA repair gene

1984 • 307 citations

Helix-turn-helix, zinc-finger, and leucine-zipper motifs for eukaryotic transcriptional regulatory proteins

1989 • 306 citations

A screening method for isolating DNA repair-deficient mutants of CHO cells

1980 • 287 citations

Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication

1989 • 286 citations

ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.

1990 • 274 citations

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

1989 • 267 citations

DNA Repair and Mutagenesis in Yeast

1981 • 242 citations

Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

1981 • 236 citations

The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA

1990 • 231 citations

RAD3 protein of Saccharomyces cerevisiae is a DNA helicase.

1987 • 222 citations

Escherichia coli helicase II (urvD gene product) translocates unidirectionally in a 3' to 5' direction.

1986 • 212 citations

Mitochondrial splicing requires a protein from a novel helicase family

1989 • 212 citations

The ATP-dependent interaction of eukaryotic initiation factors with mRNA.

1987 • 209 citations

Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells.

1988 • 193 citations

Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II

1989 • 193 citations

Nuclear protein with sequence homology to translation initiation factor eIF-4A

1988 • 190 citations

A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1

1989 • 188 citations

Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins

1986 • 187 citations

cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymerase.

1987 • 181 citations

Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

1981 • 173 citations

An eIF-4A-like protein is a suppressor of an Escherichia coli mutant defective in 50S ribosomal subunit assembly

1988 • 162 citations

TheSaccharomyces cerevisiae RAD18gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence

1988 • 147 citations

Nuclear location signal-mediated protein transport

1989 • 144 citations

Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae.

1988 • 139 citations

Molecular cloning of a mouse DNA repair gene that complements the defect of group-A xeroderma pigmentosum.

1989 • 137 citations

The RAD3 gene of Saccharomyces cerevisiae encodes a DNA-dependent ATPase.

1987 • 130 citations

Molecular cloning and biological characterization of the human excision repair gene ERCC-3.

1990 • 119 citations

Repair capability and the cellular age response for killing and mutation induction after UV

1982 • 119 citations

A DNA repair gene required for the incision of damaged DNA is essential for viability in Saccharomyces cerevisiae.

1983 • 118 citations

Mutagen-sensitive cell lines are obtained with high frequency in V79 Chinese cells

1987 • 112 citations

Isolation and characterization of the RAD3 gene of Saccharomyces cerevisiae and inviability of rad3 deletion mutants

1983 • 109 citations

Domain structure in high molecular weight high mobility group nonhistone chromatin proteins

1982 • 108 citations

The role of the polypyrimidine stretch at the SV40 early pre-mRNA 3′ splice site in alternative splicing.

1988 • 105 citations

Nucleotide sequence, transcript mapping, and regulation of the RAD2 gene of Saccharomyces cerevisiae

1986 • 97 citations

Xeroderma Pigmentosum

1988 • 97 citations

Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening

1989 • 92 citations

Differences between rodent and human cell lines in the amount of integrated DNA after transfection*1

1987 • 92 citations

Cloning and sequencing ofSchizosaccharomyces pombeDNA topoisomerase I gene, and effect of gene disruption

1987 • 85 citations

The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I

1989 • 74 citations

Stimulation of protein-directed strand exchange by a DNA helicase

1987 • 69 citations

Nuclear Proteins

1974 • 68 citations

Repair of DNA‐containing pyrimidine dimers

1988 • 66 citations

An eighth complementation group of rodent cells hypersensitive to ultraviolet radiation

1988 • 65 citations

Genetic cause of a Juvenile Form of Sandhoff Disease

1989 • 63 citations

Somatic cell genetics approach to dissecting mammalian DNA repair

1989 • 54 citations

Beta zero thalassemia caused by a base substitution that creates an alternative splice acceptor site in an intron.

1986 • 52 citations

Genetic complementation between UV-sensitive CHO mutants and xeroderma pigmentosum fibroblasts

1985 • 51 citations

Microinjection of human cell extracts corrects xeroderma pigmentosum defect.

1983 • 51 citations

DNA Repair Mutants in Higher Eukaryotes

1987 • 46 citations

Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines

1988 • 46 citations

Analysis of repair processes by the determination of the induction of cell killing and mutations in two repair-deficient Chinese hamster ovary cell lines

1986 • 42 citations

Lack of complementation between xeroderma pigmentosum complementation groups D and H

1989 • 38 citations

Transient correction of excision repair defects in fibroblasts of 9 xeroderma pigmentosum complementation groups by microinjection of crude human cell extracts

1986 • 38 citations

Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants

1988 • 37 citations

Molecular cloning and characterization of a mammalian excision repair gene that partially restores UV resistance to xeroderma pigmentosum complementation group D cells.

1989 • 34 citations

Complementation of the UV-sensitive phenotype of a xeroderma pigmentosum human cell line by transfection with a cDNA clone library.

1987 • 27 citations

Interspecies complementation analysis of xeroderma pigmentosum and UV-sensitive chinese hamster cells

1985 • 23 citations

Identification of DNA Repair Genes in the Human Genome

1986 • 13 citations

Reply to letter by J. H. Robbins

1989 • 4 citations