Expression of HLA class I-specific inhibitory receptors in human cytolytic T lymphocytes: a regulated mechanism that controls T-cell activation and function

Biology of Natural Killer Cells

1989 • 2,970 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

„Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

1975 • 1,743 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 • 871 citations

Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

1997 • 746 citations

Cloning of Immunoglobulin-Superfamily Members Associated with HLA-C and HLA-B Recognition by Human Natural Killer Cells

1995 • 735 citations

NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

1998 • 719 citations

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

1997 • 681 citations

Recruitment of Tyrosine Phosphatase HCP by the Killer Cell Inhibitory Receptor

1996 • 625 citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

1995 • 575 citations

Molecular Cloning of NKp46: A Novel Member of the Immunoglobulin Superfamily Involved in Triggering of Natural Cytotoxicity

1998 • 562 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation

1997 • 518 citations

The Ly-49 and NKR-P1 Gene Families Encoding Lectin-Like Receptors on Natural Killer Cells: The NK Gene Complex

1993 • 465 citations

IL-15: A Pleiotropic Cytokine with Diverse Receptor/Signaling Pathways Whose Expression Is Controlled at Multiple Levels

1996 • 459 citations

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

1996 • 441 citations

NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily

1999 • 437 citations

Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

1990 • 388 citations

Early Murine Cytomegalovirus (MCMV) Infection Induces Liver Natural Killer (NK) Cell Inflammation and Protection Through Macrophage Inflammatory Protein 1α (MIP-1α)–dependent Pathways

1998 • 375 citations

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

1996 • 365 citations

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.

1996 • 362 citations

A human killer inhibitory receptor specific for HLA-A1,2.

1996 • 347 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Superantigen-Dependent, Cell-Mediated Cytotoxicity Inhibited by MHC Class I Receptors on T Lymphocytes

1995 • 316 citations

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: Structural evidence for new stimulatory and inhibitory pathways

1997 • 298 citations

The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

1997 • 271 citations

Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations.

1996 • 249 citations

Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses

1998 • 245 citations

HLA class I-specific inhibitory receptors in human T lymphocytes: Interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8⁺ T cells

1998 • 237 citations

Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors

1993 • 222 citations

Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production

1995 • 221 citations

Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C.

1996 • 210 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Allorecognition by NK cells: nonself or no self?

1992 • 182 citations

Transforming growth factor-β-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes

1999 • 180 citations

Different roles for rcytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses

1996 • 171 citations

Interleukin‐15‐induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2‐A as the only HLA class I‐specific inhibitory receptor

1997 • 162 citations

p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily

1998 • 155 citations

The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity

1997 • 154 citations

T cell clones expressing the natural killer cell‐related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function

1994 • 140 citations

A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody.

1990 • 136 citations

CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies

1996 • 133 citations

Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen.

1995 • 124 citations

Reconstituted Killer Cell Inhibitory Receptors for Major Histocompatibility Complex Class I Molecules Control Mast Cell Activation Induced via Immunoreceptor Tyrosine-based Activation Motifs

1997 • 116 citations

Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones.

1996 • 112 citations

Killer cell receptors: keeping pace with MHC class I evolution

1997 • 110 citations

Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: Impairment of specific cytolytic functions

1997 • 106 citations

HLA-class I-specific inhibitory receptors in human cytolytic T lymphocytes: molecular characterization, distribution in lymphoid tissues and co-expression by individual T cells

1997 • 79 citations

Expression of two interleukin‐15 mRNA isoforms in human tumors does not correlate with secretion: role of different signal peptides

1997 • 73 citations

Cytotoxicity of Human Peripheral Lymphocytes in Cell-Mediated Lympholysis; Antibody-Dependent Cell-Mediated Lympholysis and Natural Cytotoxicity Assays after Mixed Lymphocyte Culture

1978 • 66 citations

Assignment of human natural killer (NK)‐like cells to the T cell lineage. Single allospecific T cell clones lyse specific or NK‐sensitive target cells via distinct recognition structures

1984 • 60 citations