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2001 • 3,867 citations

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The New WHO Classification of Brain Tumours

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Cloning and Expression of a Plasma Membrane Cystine/Glutamate Exchange Transporter Composed of Two Distinct Proteins

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Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

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Glutamate release promotes growth of malignant gliomas

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1993 • 512 citations

Glioma cells release excitotoxic concentrations of glutamate.

1999 • 420 citations

Strategies for reversing drug resistance

2003 • 349 citations

Compromised Glutamate Transport in Human Glioma Cells: Reduction–Mislocalization of Sodium-Dependent Glutamate Transporters and Enhanced Activity of Cystine–Glutamate Exchange

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Glutathione Peroxidase-Catalase Cooperativity Is Required for Resistance to Hydrogen Peroxide by Mature Rat Oligodendrocytes

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Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function

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Distribution of Cystine/Glutamate Exchange Transporter, System x_c⁻, in the Mouse Brain

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Necrosis and Glioblastoma: A Friend or a Foe? A Review and a Hypothesis

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Differentiation of substrate and non-substrate inhibitors of transport system xc−: an obligate exchanger of L-glutamate and L-cystine

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Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system x c -

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In vitro and In vivo Activity of the Nuclear Factor-κB Inhibitor Sulfasalazine in Human Glioblastomas

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Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells

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Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis.

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Cystine Deprivation Induces Oligodendroglial Death: Rescue by Free Radical Scavengers and by a Diffusible Glial Factor

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Malignant gliomas: perverting glutamate and ion homeostasis for selective advantage

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Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: Evidence for methylmercury‐targeted disruption of astrocyte transport

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Characterization of oligodendrogliomas using short echo time ¹H MR spectroscopic imaging

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The Mayo Clinic-Canadian cooperative trial of sulfasalazine in active multiple sclerosis

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Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.

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Astrocytes protect neurons from neurotoxic injury by serum glutamate

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Extracellular Glutamate Levels Are Chronically Elevated in the Brains of LP‐BM5‐Infected Mice: A Mechanism of Retrovirus‐Induced Encephalopathy

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Evidence for a High Free Radical State in Low-grade Astrocytomas

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Kinetic and pharmacological analysis of l-[35S]cystine transport into rat brain synaptosomes

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Ki-67 Immunoperoxidase Stain as Marker for the Histological Grading of Nervous System Tumours

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The effect of sulfasalazine on bovine endothelial cell proliferation and cell cycle phase distribution. Comparison with olsalazine, 5-aminosalicylic acid, and sulfapyridine.

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