Assembly and Cell Surface Expression of Heteromeric and Homomeric γ-Aminobutyric Acid Type A Receptors

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

1994 • 815 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

The effect of subunit composition of rat brain GABAA receptors on channel function

1990 • 592 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

1990 • 557 citations

Quaternary Structure of the Native GABA_A Receptor Determined by Electron Microscopic Image Analysis

1994 • 423 citations

GABA _A receptor subtypes: from pharmacology to molecular biology

1991 • 421 citations

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

1990 • 415 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies.

1992 • 346 citations

Functional Modulation of GABA _A Receptors by cAMP-Dependent Protein Phosphorylation

1992 • 322 citations

Regulation of GABAA receptor function by protein kinase C phosphorylation

1994 • 304 citations

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly.

1992 • 259 citations

GABAA receptor channels: from subunits to functional entities

1992 • 255 citations

Transient Expression Shows Ligand Gating and Allosteric Potentiation of GABA _A Receptor Subunits

1988 • 233 citations

Modulation of GABAA receptors by tyrosine phosphorylation

1995 • 224 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant.

1994 • 200 citations

Generation of Two Forms of the γ‐Aminobutyric Acid_A Receptor γ‐₂‐Subunit in Mice by Alternative Splicing

1991 • 196 citations

GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties

1991 • 195 citations

Single Subunits of the GABA _A Receptor Form Ion Channels with Properties of the Native Receptor

1988 • 193 citations

Ion-channel assembly.

1995 • 181 citations

GABAA receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification.

1993 • 170 citations

Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase.

1994 • 147 citations

Ion-channel assembly

1995 • 143 citations

Shift of equilibrium density induced by 3,3'-diaminobenzidine cytochemistry: a new procedure for the analysis and purification of peroxidase-containing organelles.

1984 • 132 citations

Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits.

1994 • 118 citations

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

1993 • 110 citations

Biochemical evidence for the existence of gamma-aminobutyrateA receptor iso-oligomers.

1990 • 100 citations

The Subunit Composition of a GABA_A/Benzodiazepine Receptor from Rat Cerebellum

1994 • 89 citations

The rat β₁ ‐subunit of the GABA_A receptor forms a picrotoxin‐sensitive anion channel open in the absence of GABA

1989 • 76 citations

Characterization of endocytic compartments using the horseradish peroxidase-diaminobenzidine density shift technique.

1987 • 76 citations

Further evidence for the existence of alpha subunit heterogeneity within discrete gamma-aminobutyric acidA receptor subpopulations.

1993 • 73 citations

Stable expression of mammalian type A gamma-aminobutyric acid receptors in mouse cells: demonstration of functional assembly of benzodiazepine-responsive sites.

1992 • 67 citations

Immunoaffinity purification of gamma-aminobutyric acidA (GABAA) receptors containing gamma 1-subunits. Evidence for the presence of a single type of gamma-subunit in GABAA receptors.

1994 • 57 citations

Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties

1990 • 56 citations

The α1,α2, and α3 Subunits of GABAA Receptors: Comparison in Seizure-Prone and -Resistant Mice and during Development

1992 • 43 citations

Site-directed mutagenesis of N-linked glycosylation sites on the gamma-aminobutyric acid type A receptor alpha 1 subunit.

1994 • 42 citations

GABAA receptor β1, β2, and β3 subunits: comparisons in DBA/2J and C57BL/6J mice

1995 • 30 citations