Single Subunits of the GABA _A Receptor Form Ion Channels with Properties of the Native Receptor

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

Mechanism of anion permeation through channels gated by glycine and gamma‐aminobutyric acid in mouse cultured spinal neurones.

1987 • 1,166 citations

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1980 • 608 citations

Structural and functional basis for GABAA receptor heterogeneity

1988 • 590 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium

1988 • 419 citations

Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA

1983 • 402 citations

Co-localization of GABAA receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies

1985 • 317 citations

GABA _A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors

1988 • 303 citations

The effect of capping and polyadenylation on the stability, movement and translation of synthetic messenger RNAs inXenopusoocytes

1985 • 231 citations

A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.

1984 • 208 citations

gamma-Aminobutyric acid receptor channels in adrenal chromaffin cells: a patch-clamp study.

1985 • 206 citations

Separate subunits for agonist and benzodiazepine binding in the gamma-aminobutyric acidA receptor oligomer.

1986 • 168 citations

Biophysical and pharmacological properties of cloned GABAA receptor subunits expressed in xenopus oocytes

1988 • 130 citations

The GABAA/benzodiazepine receptor is a heterotetramer of homologous alpha and beta subunits.

1987 • 101 citations

A high-conductance anion channel in adult amphibian skeletal muscle

1987 • 99 citations

[3H]Muscimol photolabels the γ-aminobutyric acid receptor binding site on a peptide subunit distinct from that labeled with benzodiazepines

1986 • 96 citations