Back to search

Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput Docking

Data up to Jan 2025

Published2003
Citations215
References35

Total Citations Per Year

Abstract

References (35)

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

1980 • 3,898 citations

A geometric approach to macromolecule-ligand interactions

1982 • 2,146 citations

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

2002 • 1,202 citations

Automatic generation of 3D-atomic coordinates for organic molecules

1990 • 502 citations

Lead discovery using molecular docking

2002 • 485 citations

Protein kinase CK2: a challenge to canons

2002 • 470 citations

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

2001 • 420 citations

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and In vitro anti‐proliferative as well as In vivo anti‐tumor activity

1989 • 414 citations

Protein kinase CK2 and its role in cellular proliferation, development and pathology

1999 • 388 citations

Joining the cell survival squad: an emerging role for protein kinase CK2

2002 • 384 citations

Casein Kinase IIα Transgene-Induced Murine Lymphoma: Relation to Theileriosis in Cattle

1995 • 384 citations

Virtual screening and fast automated docking methods

2002 • 370 citations

Strategies toward the Design of Novel and Selective Protein Tyrosine Kinase Inhibitors

1999 • 366 citations

Selfish Behavior of Restriction-Modification Systems

1995 • 365 citations

Selectivity of 4,5,6,7‐tetrabromobenzotriazole, an ATP site‐directed inhibitor of protein kinase CK2 (‘casein kinase‐2’)

2001 • 346 citations

The ENZYME data bank.

1994 • 345 citations

Structure-Based Molecular Design

1994 • 323 citations

Structure-Based Discovery of Inhibitors of Thymidylate Synthase

1993 • 322 citations

PROSITE: recent developments.

1994 • 287 citations

Different Susceptibility of Protein Kinases to Staurosporine Inhibition

1995 • 284 citations

Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

2002 • 221 citations

Deficiency in Rhabdomyosarcomas of a Factor Required for MyoD Activity and Myogenesis

1993 • 215 citations

The ENZYME data bank

1994 • 183 citations

Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones

1993 • 181 citations

The Structure-Based Design of ATP-Site Directed Protein Kinase Inhibitors

1999 • 172 citations

Structural features underlying selective inhibition of protein kinase CK2 by ATP site‐directed tetrabromo‐2‐benzotriazole

2001 • 154 citations

Toward the rational design of protein kinase casein kinase-2 inhibitors

2002 • 152 citations

The Replacement of ATP by the Competitive Inhibitor Emodin Induces Conformational Modifications in the Catalytic Site of Protein Kinase CK2

2000 • 148 citations

Inhibition of Protein Kinase CK2 by Anthraquinone-related Compounds

2003 • 83 citations

Genome annotation techniques: new approaches and challenges

2002 • 70 citations

Reviews in Computational Chemistry

2003 • 44 citations

Structure-based design of ligands for protein basic domains: application to the HIV-1 Tat protein.

1998 • 14 citations

Die Struktur der Jatamansi‐Säure

1974 • 10 citations

Application of polarography to the kinetics of aromatic cyclodehydration

1969 • 1 citations

Cited By (0)

Loading...
Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput… (2003) – Journal of Medicinal Chemistry | Metascience Observatory Explorer