Ultradeep Bisulfite Sequencing Analysis of DNA Methylation Patterns in Multiple Gene Promoters by 454 Sequencing

Genome sequencing in microfabricated high-density picolitre reactors

2005 • 7,594 citations

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

DNA methylation profiling of human chromosomes 6, 20 and 22

2006 • 1,308 citations

The essentials of DNA methylation

1992 • 960 citations

Bisulfite genomic sequencing: systematic investigation of critical experimental parameters

2001 • 745 citations

DNA methylation: past, present and future directions

2000 • 609 citations

Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate Cancer

2004 • 518 citations

DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project

2004 • 364 citations

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

2006 • 337 citations

Mapping Patterns of CpG Island Methylation in Normal and Neoplastic Cells Implicates Both Upstream and Downstream Regions inde Novo Methylation

1997 • 323 citations

Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen

2004 • 308 citations

The distribution of CpG islands in mammalian chromosomes

1994 • 254 citations

Large-Scale CpG Methylation Analysis Identifies Novel Candidate Genes and Reveals Methylation Hotspots in Acute Lymphoblastic Leukemia

2007 • 149 citations

Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg

2003 • 135 citations

Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair

2006 • 133 citations

Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer.

2003 • 120 citations

Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions

2003 • 99 citations

Discovery of novel epigenetic markers in non-Hodgkin's lymphoma

2006 • 90 citations

Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior

2006 • 84 citations

Multiplex amplification of all coding sequences within 10 cancer genes by Gene-Collector

2007 • 66 citations

Differential DNA Methylation of Gene Promoters in Small B-Cell Lymphomas

2005 • 32 citations

Differential DNA Methylation of Gene Promoters in Small B-Cell Lymphomas

2005 • 26 citations