Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions

Translating the Histone Code

2001 • 9,488 citations

DNA methylation patterns and epigenetic memory

2002 • 6,778 citations

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

1992 • 3,099 citations

Chromatin modification and epigenetic reprogramming in mammalian development

2002 • 1,870 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

Role for DNA methylation in genomic imprinting

1994 • 1,695 citations

Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation.

1992 • 1,686 citations

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

2000 • 1,493 citations

Relaxation of imprinted genes in human cancer

1993 • 792 citations

Bisulfite genomic sequencing: systematic investigation of critical experimental parameters

2001 • 745 citations

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1993 • 710 citations

The Sins of the Fathers and Mothers

1999 • 489 citations

Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'

2002 • 450 citations

Genomic Imprinting: Implications for Human Disease

1999 • 363 citations

Identification and resolution of artifacts in bisulfite sequencing

2002 • 301 citations

Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

1998 • 290 citations

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

1993 • 238 citations

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19 -associated CTCF-binding sites in colorectal cancer

2000 • 228 citations

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1993 • 228 citations

M6P/IGF2 receptor: a candidate breast tumor suppressor gene.

1996 • 205 citations

Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer

2001 • 196 citations

Conservation of a maternal-specific methylation signal at the human IGF2R locus

1995 • 116 citations

Epigenetic Heterogeneity at Imprinted Loci in Normal Populations

2001 • 99 citations

Natural selection and the function of genome imprinting: beyond the silenced minority

2000 • 86 citations

Symmetric and Asymmetric DNA Methylation in the Human IGF2–H19 Imprinted Region

2000 • 85 citations

Mechanisms of DNA-mismatch correction

1990 • 81 citations

Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting

1999 • 71 citations

Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor

1997 • 70 citations

Polymorphic and tissue-specific imprinting of the human wilms tumor gene,WT1

1997 • 26 citations

Heteroduplex Resolution Using T7 Endonuclease I in Microbial Community Analyses

2000 • 11 citations