Interactions of Leptin, GH, and Cortisol in Normal Children

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

1996 • 6,254 citations

Role of leptin in the neuroendocrine response to fasting

1996 • 3,106 citations

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

1998 • 2,333 citations

Identification of targets of leptin action in rat hypothalamus.

1996 • 1,502 citations

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.

1979 • 1,145 citations

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

1997 • 771 citations

Human Leptin Deficiency Caused by a Missense Mutation: Multiple Endocrine Defects, Decreased Sympathetic Tone, and Immune System Dysfunction Indicate New Targets for Leptin Action, Greater Central than Peripheral Resistance to the Effects of Leptin, and Spontaneous Correction of Leptin-Mediated Defects

1999 • 688 citations

Plasma Leptin Levels in Healthy Children and Adolescents: Dependence on Body Mass Index, Body Fat Mass, Gender, Pubertal Stage, and Testosterone*

1997 • 648 citations

Human leptin levels are pulsatile and inversely related to pituitary–ardenal function

1997 • 632 citations

Induction of ob Gene Expression by Corticosteroids Is Accompanied by Body Weight Loss and Reduced Food Intake

1995 • 485 citations

Estrogen increases in vivo leptin production in rats and human subjects

1997 • 482 citations

Insulin and Cortisol Promote Leptin Production in Cultured Human Fat Cells

1996 • 464 citations

Leptin Inhibition of the Hypothalamic-Pituitary-Adrenal Axis in Response to Stress¹

1997 • 460 citations

Serum leptin levels in women with anorexia nervosa.

1996 • 400 citations

Serum Leptin in Children With Obesity: Relationship to Gender and Development

1996 • 394 citations

Plasma Leptin Levels in Healthy Children and Adolescents: Dependence on Body Mass Index, Body Fat Mass, Gender, Pubertal Stage, and Testosterone

1997 • 379 citations

Contribution of androgens to the gender difference in leptin production in obese children and adolescents.

1997 • 359 citations

Regulation of in VivoGrowth Hormone Secretion by Leptin

1997 • 351 citations

Activation of β3 Adrenergic Receptors Suppresses Leptin Expression and Mediates a Leptin-Independent Inhibition of Food Intake in Mice

1996 • 315 citations

Leptin and Leptin Receptor Expression in Rat and Mouse Pituitary Cells1

2000 • 245 citations

The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes.

1996 • 245 citations

Gender Differences in Both Spontaneous and Stimulated Leptin Secretion by Human Omental Adipose Tissue in Vitro: Dexamethasone and Estradiol Stimulate Leptin Release in Women, But Not in Men1

1998 • 226 citations

Dexamethasone Increases Leptin Expression in Humans in Vivo

1997 • 182 citations

Serum leptin levels in women with anorexia nervosa

1996 • 180 citations

Effects of Gender, Ethnicity, Body Composition, and Fat Distribution on Serum Leptin Concentrations in Children¹

1997 • 167 citations

Leptin Inhibition of the Hypothalamic-Pituitary-Adrenal Axis in Response to Stress

1997 • 154 citations

Isoproterenol and Somatostatin Decrease Plasma Leptin in Humans: A Novel Mechanism Regulating Leptin Secretion¹

1997 • 128 citations

Leptin Levels and Body Fatness in Children: Effects of Gender, Ethnicity, and Sexual Development1

1997 • 102 citations

Leptin Concentrations, Sex Hormones, and Cortisol in Nondiabetic Men1

1997 • 100 citations

Influence of metabolic substrates and obesity on growth hormone secretion

1995 • 99 citations

Effects of Gender, Ethnicity, Body Composition, and Fat Distribution on Serum Leptin Concentrations in Children

1997 • 92 citations

Gender Differences in Both Spontaneous and Stimulated Leptin Secretion by Human Omental Adipose Tissue in Vitro: Dexamethasone and Estradiol Stimulate Leptin Release in Women, But Not in Men

1998 • 88 citations

Isoproterenol and Somatostatin Decrease Plasma Leptin in Humans: A Novel Mechanism Regulating Leptin Secretion

1997 • 88 citations

Leptin Inhibitsin VitroHypothalamic Somatostatin Secretion and Somatostatin mRNA Levels

1997 • 84 citations

Serum leptin is increased in growth hormone—deficient adults: Relation to body composition and effects of placebo-controlled growth hormone therapy for 1 year

1997 • 84 citations

Elevated leptin concentrations in growth hormone-deficient hypopituitary adults

1997 • 70 citations

Leptin and the Perioperative Neuroendocrinological Stress Response¹

1999 • 63 citations

Plasma Leptin Levels Do not Change in Patients with Cushing’s Disease Shortly after Correction of Hypercortisolism

1997 • 62 citations

Serum Leptin Levels Correlate with Growth Hormone Secretion and Body Fat in Children*

1999 • 60 citations

Determinants of Serum Leptin Levels in Cushing’s Syndrome

1998 • 58 citations

The Relationship between Growth Hormone Kinetics and Sarcopenia in Postmenopausal Women: The Role of Fat Mass and Leptin1

1998 • 57 citations

Serum Leptin Response to the Acute and Chronic Administration of Growth Hormone (GH) to Elderly Subjects with GH Deficiency1

1999 • 53 citations

Leptin Concentrations, Sex Hormones, and Cortisol in Nondiabetic Men

1997 • 49 citations

Upregulation of Leptin Receptor Gene Expression in the Anterior Pituitary of Human Growth Hormone-Releasing Hormone Transgenic Mice

1998 • 43 citations

Direct Modification of Somatotrope Function by Long-Term Leptin Treatment of Primary Cultured Ovine Pituitary Cells

2001 • 42 citations

The Acute Leptin Response to GH

2001 • 40 citations

Serum Leptin Levels Correlate with Growth Hormone Secretion and Body Fat in Children

1999 • 37 citations

Leptin Levels in Protracted Critical Illness: Effects of Growth Hormone-Secretagogues and Thyrotropin-Releasing Hormone¹

1998 • 36 citations

Leptin and the Perioperative Neuroendocrinological Stress Response

1999 • 34 citations

Plasma Leptin Levels Do not Change in Patients with Cushing's Disease Shortly after Correction of Hypercortisolism

1997 • 34 citations

Effects of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue

1999 • 34 citations

Interactions of Leptin and Thyrotropin 24-Hour Secretory Profiles in Short Normal Children

2001 • 32 citations

Leptin Levels in Protracted Critical Illness: Effects of Growth Hormone-Secretagogues and Thyrotropin-Releasing Hormone

1998 • 28 citations

Determinants of Serum Leptin Levels in Cushing's Syndrome

1998 • 27 citations

Serum Leptin Response to the Acute and Chronic Administration of Growth Hormone (GH) to Elderly Subjects with GH Deficiency

1999 • 26 citations

Leptin, Cortisol, and GH Secretion Interactions in Short Normal Prepubertal Children

2001 • 23 citations

The Relationship between Growth Hormone Kinetics and Sarcopenia in Postmenopausal Women: The Role of Fat Mass and Leptin

1998 • 22 citations

The Acute Leptin Response to GH

2001 • 17 citations

Upregulation of Leptin Receptor Gene Expression in the Anterior Pituitary of Human Growth Hormone-Releasing Hormone Transgenic Mice

1998 • 11 citations

Leptin, Cortisol, and GH Secretion Interactions in Short Normal Prepubertal Children

2001 • 10 citations

Interactions of Leptin and Thyrotropin 24-Hour Secretory Profiles in Short Normal Children

2001 • 7 citations