Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

G _olf : an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction

1989 • 863 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

G proteins control diverse pathways of transmembrane signaling ¹

1989 • 399 citations

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

1985 • 391 citations

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

1986 • 380 citations

Isolation and characterization of the human Gs alpha gene.

1988 • 379 citations

Human cDNA clones for four species of G alpha s signal transduction protein.

1986 • 370 citations

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

1986 • 341 citations

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

1986 • 319 citations

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

1988 • 275 citations

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

1988 • 251 citations

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

1988 • 207 citations

Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex.

1985 • 205 citations

Carboxyl Rerminal Domain of G _sα Specifies Coupling of Receptors to Stimulation of Adenylyl Cyclase

1988 • 174 citations

Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go

1988 • 153 citations

Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go.

1990 • 147 citations

Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein.

1990 • 146 citations

Localization of mRNAs encoding the α‐subunits of signal‐transducing G‐proteins within rat brain and among peripheral tissues

1987 • 130 citations

Human c-ros-1 Gene Homologous to the v-ros Sequence of UR2 Sarcoma Virus Encodes for a Transmembrane Receptorlike Molecule

1986 • 119 citations

G_o, a GTP‐Binding Protein: Immunochemical and Immunohistochemical Localization in the Rat

1988 • 105 citations

Identification by molecular cloning of two forms of the α‐subunit of the human liver stimulatory (G_s) regulatory component of adenylyl cyclase

1986 • 96 citations

Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

1987 • 95 citations

Immunological and Molecular Characterization of Goα-like Proteins in the Drosophila Central Nervous System

1989 • 90 citations

The Drosophila Go α-like G protein gene produces multiple transcripts and is expressed in the nervous system and in ovaries

1989 • 74 citations

Molecular characterization of Drosophila Gene Encoding G0 α Subunit Homolog

1989 • 72 citations

Characterization of the mouse rod transducin α subunit gene

1989 • 59 citations

Molecular cloning and sequence determination of a cDNA coding for the α‐subunit of a G_o‐type protein of Xenopus laevis oocytes

1989 • 57 citations

Identification of both G_i2 and a novel, immunologically distinct, form of G_o in rat myometrial membranes

1989 • 30 citations

Structures of the Genes Coding for G-protein a Subunits from Mammalian and Yeast Cells

1988 • 25 citations

Elevated levels of the guanine nucleotide binding protein, G_o, are associated with differentiation of neuroblastoma × glioma hybrid cells

1989 • 24 citations

Molecular cloning and DNA sequence analysis of the human guanine nucleotide-binding protein Goα

1988 • 22 citations

Expression of Go.alpha. mRNA and protein in bovine tissues

1989 • 21 citations

Multiple forms of Go.alpha. mRNA: analysis of the 3'-untranslated regions

1990 • 19 citations

Primary structure of bovine cerebellum GTP‐binding protein G₃₉ and its effect on the adenylate cyclase system

1987 • 13 citations