RNA polymerase II transcription cycles

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Transcriptional regulation

1991 • 893 citations

RNA POLYMERASE II

1991 • 729 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

1992 • 407 citations

Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene Promoter

1988 • 320 citations

Tails of RNA polymerase II

1990 • 320 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II

1987 • 306 citations

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

1987 • 288 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function.

1988 • 246 citations

The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa

1989 • 236 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II.

1988 • 212 citations

TATA-binding protein is a classless factor

1992 • 202 citations

CTD kinase associated with yeast RNA polymerase II initiation factor b

1991 • 199 citations

Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.

1990 • 178 citations

The small subunit of transcription factor IIF recruits RNA polymerase II into the preinitiation complex.

1991 • 178 citations

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

1991 • 170 citations

A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID

1992 • 170 citations

Phosphorylation of eukaryotic DNA-dependent RNA polymerase. Identification of calf thymus RNA polymerase subunits phosphorylated by two purified protein kinases, correlation with in vivo sites of phosphorylation in HeLa cell RNA polymerase II.

1981 • 159 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

A three-dimensional model of hepatitis delta virus ribozyme based on biochemical and mutational analyses

1994 • 145 citations

Advances in RNA polymerase II transcription

1992 • 144 citations

Cloning of the 62-Kilodalton Component of Basic Transcription Factor BTF2

1992 • 120 citations

Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1991 • 117 citations

Transcription-dependent Structural Changes in the C-terminal Domain of Mammalian RNA Polymerase Subunit IIa/o

1989 • 97 citations

Immunochemical analysis of mammalian RNA polymerase II subspecies. Stability and relative in vivo concentration.

1986 • 89 citations

Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1991 • 85 citations

The Major Late Promoter of Adenovirus-2 Is Accurately Transcribed by RNA Polymerases IIO, IIA, and IIB

1989 • 83 citations

Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase

1992 • 77 citations

Partial purification and characterization of two distinct protein kinases that differentially phosphorylate the carboxyl-terminal domain of RNA polymerase subunit IIa.

1993 • 75 citations

Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. Association with transcriptional initiation

1991 • 73 citations

Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex.

1991 • 70 citations

Transcription initiation complexes and upstream activation with RNA polymerase II lacking the C-terminal domain of the largest subunit.

1990 • 53 citations

Mechanism of assembly of the RNA polymerase II preinitiation complex. Transcription factors delta and epsilon promote stable binding of the transcription apparatus to the initiator element.

1992 • 46 citations

[24] Purification of protein kinases that phosphorylate the repetitive carboxyl-terminal domain of eukaryotic RNA polymerase II

1991 • 45 citations

The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro.

1990 • 44 citations

RNA polymerase-associated transcription factors

1991 • 42 citations

Mechanism of assembly of the RNA polymerase II preinitiation complex. Evidence for a functional interaction between the carboxyl-terminal domain of the largest subunit of RNA polymerase II and a high molecular mass form of the TATA factor.

1992 • 40 citations

Yeast RNA polymerase II initiation factor e: isolation and identification as the functional counterpart of human transcription factor IIB.

1992 • 39 citations

A protein kinase from wheat germ that phosphorylates the largest subunit of RNA polymerase II.

1989 • 37 citations

Heat‐shock and related stress enhance RNA polymerase II C‐terminal‐domain kinase activity in HeLa cell extracts

1990 • 32 citations

Protein kinases from Aspergillus nidulans that phosphorylate the carboxyl-terminal domain of the largest subunit of RNA polymerase II.

1992 • 26 citations

Conservation of the mammalian RNA polymerase II largest-subunit C-terminal domain

1992 • 22 citations