Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias

2002 • 3,947 citations

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

2001 • 3,799 citations

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

2000 • 3,241 citations

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

2005 • 2,964 citations

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

2000 • 2,696 citations

Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment

2000 • 2,535 citations

Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

2000 • 1,933 citations

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

2001 • 1,283 citations

Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis

2007 • 1,249 citations

Idiopathic Pulmonary Fibrosis

2001 • 956 citations

The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress

2005 • 934 citations

A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease

2001 • 888 citations

Mechanisms of Pulmonary Fibrosis

2004 • 714 citations

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

2002 • 635 citations

Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

2000 • 551 citations

Hydrophobic Surfactant Proteins in Lung Function and Disease

2002 • 493 citations

Activation of ATF6 and an ATF6 DNA Binding Site by the Endoplasmic Reticulum Stress Response

2000 • 485 citations

Clinical and Pathologic Features of Familial Interstitial Pneumonia

2005 • 406 citations

Herpesvirus DNA Is Consistently Detected in Lungs of Patients with Idiopathic Pulmonary Fibrosis

2003 • 301 citations

Human Cytomegalovirus Infection Activates and Regulates the Unfolded Protein Response

2005 • 281 citations

Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF

2004 • 267 citations

A Surfactant Protein C Precursor Protein BRICHOS Domain Mutation Causes Endoplasmic Reticulum Stress, Proteasome Dysfunction, and Caspase 3 Activation

2005 • 250 citations

SURFACTANT PROTEIN C BIOSYNTHESIS AND ITS EMERGING ROLE IN CONFORMATIONAL LUNG DISEASE

2004 • 196 citations

The Detection of Epstein-Barr Virus DNA in Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis

1999 • 195 citations

Characterization of Fibroblast-specific Protein 1 in Pulmonary Fibrosis

2004 • 167 citations

Epstein-Barr virus replication within pulmonary epithelial cells in cryptogenic fibrosing alveolitis.

1995 • 164 citations

Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ ₁ 34.5 Protein

2005 • 159 citations

Misfolded BRICHOS SP-C mutant proteins induce apoptosis via caspase-4- and cytochrome c-related mechanisms

2007 • 127 citations

Involvement of Epstein-Barr virus latent membrane protein 1 in disease progression in patients with idiopathic pulmonary fibrosis

2000 • 99 citations

The Genetic Approach in Pulmonary Fibrosis: Can It Provide Clues to This Complex Disease?

2006 • 79 citations

Quantitative measurement of events in the mammalian unfolded protein response

2005 • 45 citations

Constitutively Active K-cyclin/cdk6 Kinase in Kaposi Sarcoma–Associated Herpesvirus–Infected Cells

2005 • 42 citations

BK and JC Polyomaviruses Are Not Associated with Idiopathic Pulmonary Fibrosis

2005 • 12 citations