Determination of Protein Carbonyl Groups by Immunoblotting

[49] Determination of carbonyl content in oxidatively modified proteins

1990 • 5,654 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Protein Oxidation and Aging

1992 • 2,687 citations

[37] Carbonyl assays for determination of oxidatively modified proteins

1994 • 2,605 citations

[38] Oxidative damage to proteins: Spectrophotometric method for carbonyl assay

1994 • 2,372 citations

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

1991 • 1,290 citations

Age-related changes in oxidized proteins.

1987 • 1,229 citations

Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences

1990 • 1,143 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

1994 • 785 citations

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1991 • 734 citations

Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure.

1987 • 572 citations

Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.

1987 • 482 citations

Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease

1996 • 481 citations

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing

1983 • 467 citations

Differential susceptibility of plasma proteins to oxidative modification: Examination by western blot immunoassay

1994 • 464 citations

Covalent modification reactions are marking steps in protein turnover

1990 • 211 citations

Increased carbonyl content of proteins in synovial fluid from patients with rheumatoid arthritis.

1989 • 143 citations

Protein Oxidation and Aging 1. Difficulties in Measuring Reactive Protein Carbonyls in Tissues Using 2,4-Dinitrophenylhydrazine

1995 • 138 citations

Oxidation of proteins in neonatal lungs.

1994 • 122 citations

Immunochemical detection of oxidized proteins

1993 • 116 citations

Oxidation of Proteins in Neonatal Lungs

1994 • 107 citations

Differential oxidative damage to mitochondrial proteins during aging

1995 • 74 citations

Optimization of the histochemical demonstration of DNA using 3-hydroxy-2-naphthoic acid hydrazide and Fast Blue B

1989 • 9 citations