Lymphokine stimulation of collagen accumulation.

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Selective enzyme purification by affinity chromatography.

1968 • 1,211 citations

Pathologic observations in systemic sclerosis (scleroderma)

1969 • 1,071 citations

A specific method for the analysis of hydroxyproline in tissues and urine

1960 • 1,065 citations

Modified procedure for the assay of H3- or C14-labeled hydroxyproline

1966 • 710 citations

“Lymphokines”: Non-Antibody Mediators of Cellular Immunity generated by Lymphocyte Activation

1969 • 575 citations

Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLAST

1974 • 545 citations

Systemic Scleroderma

1961 • 536 citations

A one-stage procedure for isolation of granulocytes and lymphocytes from human blood. General sedimentation properties of white blood cells in a 1g gravity field.

1968 • 492 citations

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1964 • 339 citations

Lymphocyte in vitro cytotoxicity: mechanisms of immune and nonimmune small lymphocyte mediated target L cell destruction

1968 • 230 citations

Cell-Mediated Cytotoxicity to Muscle in Polymyositis

1973 • 180 citations

Thyroid Peroxidase and Thyroxine Biosynthesis

1970 • 157 citations

Serum antinuclear antibodies in progressive systemic sclerosis (scleroderma)

1968 • 143 citations

HOMOLOGOUS DISEASE IN THE ADULT RAT, A MODEL FOR AUTOIMMUNE DISEASE

1963 • 131 citations

Lymphocyte transformation in vitro. I. Tissue culture conditions and quantitative measurements.

1968 • 130 citations

Skeletal muscle involvement in progressive systemic sclerosis (scleroderma)

1968 • 130 citations

Evidence of microvascular injury in scleroderma and systemic lupus erythematosus: quantitative study of the microvascular bed.

1968 • 128 citations

Lymphotoxin formation by lymphocytes and muscle in polymyositis

1972 • 127 citations

A Hydroxyproline-containing, Collagen-like Protein in Plasma and a Procedure for Its Assay

1964 • 124 citations

GROWTH-PROMOTING FUNCTION OF LEUCOCYTES

1922 • 123 citations

Pathology of the Connective Tissue Diseases.

1966 • 118 citations

Scleroderma and the Subcutaneous Tissue

1971 • 116 citations

Human Lymphocyte Response to Phytomitogens in Vitro: Normal, Agammaglobulinemic and Paraproteinemic Individuals

1969 • 101 citations

Functional and morphologic alterations of the gastrointestinal tract in progressive systemic sclerosis (scleroderma)

1962 • 96 citations

Immunological Aspects of Polymyositis<subtitle>THE <italic>IN VITRO</italic> ACTIVITY OF LYMPHOCYTES ON INCUBATION WITH MUSCLE ANTIGEN AND WITH MUSCLE CULTURES</subtitle>

1971 • 94 citations

The Nature of Joint Involvement in Progressive Systemic Sclerosis (Diffuse Scleroderma)

1962 • 91 citations

The natural history of progressive systemic sclerosis (diffuse scleroderma).

1963 • 87 citations

Antinucleolar Antibodies

1970 • 71 citations

The rheumatic manifestaions of progressive systemic sclerosis (scleroderma).

1968 • 70 citations

Pathogenesis of postnecrotic cirrhosis in alcoholics.

1962 • 63 citations

Connective Tissue Activation. I. The Nature, Specificity, Measurement and Distribution of Connective Tissue Activating Peptide

1971 • 60 citations

Leukocyte‐connective tissue cell interaction. I. Stimulation of hyaluronate synthesis by live and dead leukocytes

1969 • 49 citations

IMMUNOLOGICAL ASPECTS OF SYSTEMIC SCLEROSIS: IN VITRO ACTIVITY OF LYMPHOCYTES FROM PATIENTS WITH THE DISORDER

1971 • 46 citations

Relationship of cloning inhibition factor, "lymphotoxin" factor, and proliferation inhibition factor release in vitro by mitogen-activated human lymphoctes.

1975 • 45 citations

8 The Rheumatic Manifestations of Progressive Systemic Sclerosis (Scleroderma)

1968 • 41 citations

Studies on in vitro models of cellular immunity: The role of T and B cells in the secretion of lymphotoxin

1973 • 40 citations

Leukocyte‐connective tissue cell interaction. II. The specificity, duration, and mechanism of interaction effects

1969 • 40 citations

Serologic alterations in scleroderma and sclerodermatomyositis.

1971 • 40 citations

Recommendations concerning the use of bacterial collagenase for isolating collagen-associated molecules from tissues

1973 • 38 citations

URACIL-SPECIFIC ANTI-R.N.A. ANTIBODIES IN SCLERODERMA

1975 • 37 citations

II. Separation of antibody-active proteins from various animal sera by ethanol fractionation techniques.

1952 • 35 citations

The turnover of collagen in fibroblast cultures

1973 • 35 citations

Studies of endogenous catecholamines in patients with Raynaud's phenomenon secondary to progressive systemic sclerosis (scleroderma)

1972 • 34 citations

Relationship of Cloning Inhibition Factor, “Lymphotoxin” Factor, and Proliferation Inhibition Factor Release in Vitro by Mitogen-Activated Human Lymphocytes

1975 • 33 citations

Synovial tissue changes and rheumatoid factor in scleroderma.

1971 • 31 citations

Phenylketonuria and scleroderma

1968 • 28 citations

Antinuclear antibodies: their significance in scleroderma.

1971 • 27 citations

The Effects of Lymphocytes, Sera and Long-Acting Thyroid Stimulator from Patients with Graves' Disease on Retrobular Fibroblasts

1973 • 26 citations

Some aspects of the pathology of collagen diseases.

1956 • 26 citations

Methylcellulose effect on cell proliferation and glucose utilization in chemically defined medium in large stationary cultures

1969 • 25 citations

Skin blood flow in scleroderma.

1970 • 22 citations

AUTOANTIBODIES IN SCLERODERMA

1968 • 21 citations

Connective tissue activation. V. The flux of connective tissue activating peptide during acute inflammation.

1973 • 18 citations

Lymphocyte activation. 3. The prolonged requirement for mitogen in phytohaemagglutinin- and concanavalin A-stimulated cultures.

1973 • 18 citations

Culture conditions affecting induction and release of lymphocyte produced proliferation inhibitory factor (PIF)

1973 • 17 citations

Endocrine Exophthalmos

1962 • 15 citations

Lymphokines--the mediators of cellular immunity.

1972 • 15 citations

Urinary 5-hydroxyindoleacetic Acid Excretion in Scleroderma**From the Division of Dermatology, Department of Medicine, University of Southern California School of Medicine, Los Angeles, California.

1963 • 13 citations

Immunoglobulins in systemic scleroderma.

1971 • 12 citations

Polymyositis and Cell-Mediated Immunity

1973 • 8 citations

Urinary 5-Hydroxyindoleacetic Acid Excretion in Scleroderma

1963 • 2 citations