Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists.

[10] Assay of inorganic phosphate, total phosphate and phosphatases

1966 • 3,302 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.

1982 • 542 citations

The regulatory component of adenylate cyclase. Purification and properties.

1981 • 505 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

(�)[125Iodo]cyanopindolol, a new ligand for ?-adrenoceptors: Identification and quantitation of subclasses of ?-adrenoceptors in guinea pig

1981 • 387 citations

Mammalian .beta.2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

1984 • 249 citations

Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.

1976 • 240 citations

Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.

1985 • 213 citations

Reconstitution of catecholamine-stimulated guanosine triphosphatase activity

1983 • 213 citations

The effect of epinephrine and other agents on adenyl cyclase in the cell membrane of avian erythrocytes

1966 • 196 citations

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

1977 • 173 citations

Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

1979 • 171 citations

Affinity chromatography of the beta-adrenergic receptor.

1979 • 156 citations

Adenyl Cyclase of Rat Parotid Gland

1970 • 149 citations

GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediates.

1985 • 143 citations

Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase

1984 • 136 citations

The insulin receptor protein kinase. Physicochemical requirements for activity.

1983 • 119 citations

Evidence for essential disulfide bonds in beta1-adrenergic receptors of turkey erythrocyte membranes. Inactivation by dithiothreitol.

1979 • 101 citations

Functional reconstitution of beta-adrenergic receptors and the stimulatory GTP-binding protein of adenylate cyclase.

1982 • 100 citations

Transfer of glucagon receptor from liver membranes to a foreign adenylate cyclase by a membrane fusion procedure

1979 • 89 citations

Locking of hormone in the beta-adrenergic receptor by attack on a sulfhydryl in an associated component.

1982 • 88 citations

Delipidation of a beta-adrenergic receptor preparation and reconstitution by specific lipids.

1983 • 76 citations

Effects of magnesium and N-ethylmaleimide on the binding of 3H-hydroxybenzylisoproterenol to beta-adrenergic receptors.

1982 • 62 citations

Inactivation of beta-adrenergic receptors by N-ethylmaleimide: permissive role of beta-adrenergic agents in relation to adenylate cyclase activation.

1980 • 46 citations

Catecholamine-stimulated guanosine 5'-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles

1984 • 43 citations

Chemical modification of the beta adrenergic receptors coupled with adenylate cyclase by disulfide bridge-reducing agents.

1978 • 40 citations

Inactivation of beta-adrenergic receptors by N-ethylmaleimide in S49 lymphoma cells. Agonist induction of functional receptor heterogeneity.

1980 • 39 citations

The β-adrenergic receptor of turkey erythrocyte membranes: Conformational modification by β-adrenergic agonists

1979 • 37 citations

Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. beta-Adrenergic and PGE1 receptors in parental and hybrid cells.

1977 • 29 citations

Interaction between beta-adrenergic receptors and guanine nucleotide sites in turkey erythrocyte membranes.

1980 • 28 citations

Inactivation of the β-adrenergic receptor in skeletal muscle by dithiols

1983 • 24 citations