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Obesity and immune function relationships

Data up to Jan 2025

Published2001
Citations405
References90

Total Citations Per Year

Abstract

References (90)

Obesity : Preventing and managing the global epidemic

2000 • 12,240 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Role of leptin in the neuroendocrine response to fasting

1996 • 3,106 citations

Understanding Adipocyte Differentiation

1998 • 2,292 citations

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

1998 • 2,143 citations

Leptin regulates proinflammatory immune responses

1998 • 1,161 citations

Is Type II diabetes mellitus a disease of the innate immune system?

1998 • 1,040 citations

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2000 • 962 citations

Synergism of nutrition, infection, and immunity: an overview

1997 • 929 citations

Nutrition and the immune system: an introduction

1997 • 865 citations

Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.

1996 • 864 citations

Multiple Cytokines and Acute Inflammation Raise Mouse Leptin Levels: Potential Role in Inflammatory Anorexia

1997 • 798 citations

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

1996 • 751 citations

Obesity in the new millennium

2000 • 707 citations

Human Leptin Stimulates Proliferation and Activation of Human Circulating Monocytes

1999 • 588 citations

Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

1999 • 558 citations

Leptin regulates proinflammatory immune responses

1998 • 487 citations

Physical activity and immune function in elderly women

1993 • 405 citations

The etiology of obesity: relative contribution of metabolic factors, diet, and physical activity

1998 • 399 citations

Influence of Obesity on Immune Function

1999 • 342 citations

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1985 • 333 citations

A role for preadipocytes as macrophage‐like cells

1999 • 319 citations

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1999 • 252 citations

Concepts in Functional Foods: The Case of Inulin and Oligofructose

1999 • 244 citations

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1999 • 221 citations

Leptin and the immune system: how nutritional status influences the immune response.

2000 • 213 citations

Impaired immunity in obesity: suppressed but reversible lymphocyte responsiveness.

1993 • 207 citations

Total and Differential Leukocyte Counts as Predictors of Ischemic Heart Disease: The Caerphilly and Speedwell Studies

1997 • 204 citations

Interleukin 1α Increases Serum Leptin Concentrations in Humans

1997 • 203 citations

Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor

1999 • 190 citations

Cell-mediated immunity in genetically obese (C57BL/6J ob/ob) mice

1980 • 178 citations

Phenotypic abnormalities in macrophages from leptin-deficient, obese mice

1999 • 166 citations

Impairment of Cell-Mediated Immunity in Mutation Diabetic Mice (db/db)

1978 • 159 citations

Obesity, Diabetes and Functions for Proopiomelanocortin-derived Peptides

1997 • 152 citations

Leptin Stimulates Fetal and Adult Erythroid and Myeloid Development

1997 • 144 citations

Immune response to exercise training and/or energy restriction in obese women

1998 • 125 citations

Immune response to obesity and moderate weight loss.

1996 • 118 citations

Immunology

2000 • 117 citations

Leptin and Interleukin-6 in Sepsis

1998 • 113 citations

The beneficial effects of body fat and adipose tissue in humans*

1997 • 109 citations

Significance of obesity on nutritional, immunologic, hormonal, and clinical outcome parameters in burns

1993 • 106 citations

IMMUNOCOMPETENCE IN OBESITY

1980 • 106 citations

Effect of body weight and caloric restriction on serum complement proteins, including Factor D/adipsin: studies in anorexia nervosa and obesity

1997 • 102 citations

Progress in obesity research: 8

1999 • 96 citations

White Blood Cell Counts in Persons Aged 65 Years or More from the Cardiovascular Health Study: Correlations with Baseline Clinical and Demographic Characteristics

1996 • 91 citations

Fasting-enhanced immune effector mechanisms in obese subjects

1983 • 81 citations

Increased Leptin Expression in Mice with Bacterial Peritonitis is Partially Regulated by Tumor Necrosis Factor Alpha

1998 • 79 citations

Novel pathophysiological aspects of macrophage migration inhibitory factor (review).

1998 • 79 citations

CONCEPTS IN FUNCTIONAL FOODS

1999 • 74 citations

Nutrient Modulation of the Immune Response

2020 • 73 citations

Leptin: physiological actions.

1999 • 73 citations

Nutrient Modulation of the Immune Response

1994 • 72 citations

Association between insulin resistance, body mass and neopterin concentrations

1999 • 71 citations

T Lymphopenia in Genetically Obese Rats

1998 • 68 citations

Interleukin 1 Increases Serum Leptin Concentrations in Humans

1997 • 68 citations

Metabolic Abnormalities and the Role of Leptin in Human Obesity

1999 • 62 citations

Effects of weight loss and exercise training on natural killer cell activity in obese women

1998 • 59 citations

Impaired Immunogenicity of Hepatitis B Vaccine in Obese Persons

1986 • 59 citations

Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor

1999 • 56 citations

OBESITY: A Major Global Public Health Problem

1999 • 49 citations

Polymorphonuclear (PMN) Function after Small Intestinal Shunt Operation for Morbid Obesity

1980 • 48 citations

Obesity in young Europeans: genetic and environmental influences

2000 • 47 citations

Use of Very Low‐Calorie Diet in Preoperative Weight Loss: Efficacy and Safety

1997 • 44 citations

Interactions between nutrition and immunity in anorexia nervosa: a 1-y follow-up study

1997 • 42 citations

Regulation of energy balance and adiposity: a model with new approaches.

1996 • 42 citations

Resonant tunneling in asymmetrical double-barrier structures under an applied electric field

1998 • 41 citations

Energy restriction decreases number of circulating natural killer cells and serum levels of immunoglobulins in overweight women.

1994 • 41 citations

Spleen Hemolytic Plaque-Forming Cell Response and Generation of Cytotoxic Cells in Genetically Obese (C57B1/6J <i>ob</i>/<i>ob</i>) Mice

1980 • 37 citations

Exercise training restores decreased cellular immune functions in obese Zucker rats

1998 • 37 citations

Decreased mitogen response of splenic lymphocytes in obese Zucker rats is associated with the decreased expression of glucose transporter 1 (GLUT-1)

1998 • 36 citations

Leptin: Physiological actions

1999 • 33 citations

Endocrine regulation of uncoupling proteins and energy expenditure

2000 • 32 citations

The mahogany mouse mutation: further links between pigmentation, obesity and the immune system

1999 • 32 citations

Human immunodeficiency virus infection and nutritional status in female drug addicts undergoing detoxification: anthropometric and immunologic assessments

1997 • 32 citations

Evaluation of nutritional status by immunologic assessment in bulimia nervosa: influence of body mass index and vomiting episodes

1997 • 30 citations

Relationship between the fatty acid composition of rat lymphocytes and immune functions

2000 • 27 citations

Is obesity contagious?

1998 • 27 citations

Obesity is a risk factor for deteriorating cellular immune functions decreased with aging

1995 • 24 citations

Indices of height and weight as measures of obesity.

1970 • 24 citations

Nutritional outcome and immunocompetence in mice fed on a diet containing raw field beans (Vicia faba, var. minor) as the source of protein

1992 • 22 citations

Immunonutrition

1997 • 21 citations

The Effect of Surgically Induced Weight Reduction on the Serum Levels of the Cytokines: Interleukin-3 and Tumor Necrosis Factor

1999 • 21 citations

Immune response decisions at the single cell level

1997 • 20 citations

Metabolic Abnormalities and the Role of Leptin in Human Obesity

1999 • 20 citations

Cross-sectional assessment of nutritional and immune status in renal patients undergoing continuous ambulatory peritoneal dialysis

1997 • 18 citations

Nutrition and immunity.

1988 • 16 citations

Amino acid residues required for binding of vascular cell adhesion molecule-1 to integrin alpha 4 beta 7

1997 • 8 citations

Update in Allergy and Immunology

1998 • 6 citations

Update in Allergy and Immunology

2000 • 3 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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