The Corepressors Silencing Mediator of Retinoid and Thyroid Hormone Receptor and Nuclear Receptor Corepressor Are Involved in Agonist- and Antagonist-Regulated Transcription by Androgen Receptor

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Cancer statistics, 2000

2000 • 3,907 citations

The coregulator exchange in transcriptional functions of nuclear receptors

2000 • 2,219 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

Analysis of gene function in somatic mammalian cells using small interfering RNAs

2002 • 1,108 citations

Androgen Receptor (AR) Coregulators: An Overview

2002 • 876 citations

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

1998 • 667 citations

Formation of the Androgen Receptor Transcription Complex

2002 • 657 citations

Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen

1997 • 640 citations

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

2000 • 625 citations

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

2002 • 588 citations

Combinatorial Roles of the Nuclear Receptor Corepressor in Transcription and Development

2000 • 502 citations

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

2000 • 482 citations

Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

2001 • 474 citations

The program of androgen-responsive genes in neoplastic prostate epithelium

2002 • 473 citations

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

2003 • 427 citations

The AF1 and AF2 Domains of the Androgen Receptor Interact with Distinct Regions of SRC1

1999 • 418 citations

The N-CoR-HDAC3 Nuclear Receptor Corepressor Complex Inhibits the JNK Pathway through the Integral Subunit GPS2

2002 • 407 citations

N-CoR Mediates DNA Methylation-Dependent Repression through a Methyl CpG Binding Protein Kaiso

2003 • 395 citations

Dehydroepiandrosterone Activates Mutant Androgen Receptors Expressed in the Androgen-Dependent Human Prostate Cancer Xenograft CWR22 and LNCaP Cells

1997 • 351 citations

Minireview: Nuclear Receptor Coactivators—An Update

2002 • 340 citations

Biological roles and mechanistic actions of co-repressor complexes

2002 • 323 citations

N-CoR controls differentiation of neural stem cells into astrocytes

2002 • 305 citations

Transcriptional Repression by Nuclear Hormone Receptors

2000 • 291 citations

The Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription

1999 • 268 citations

Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins

1999 • 262 citations

THE BIOLOGY OF HORMONE REFRACTORY PROSTATE CANCER

1999 • 256 citations

Aberrant response in vitro of hormone‐responsive prostate cancer cells to antiandrogens

1989 • 208 citations

Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor

2005 • 201 citations

Coregulator Recruitment and Histone Modifications in Transcriptional Regulation by the Androgen Receptor

2004 • 190 citations

Androgen Receptor (AR) Coregulators: An Overview

2002 • 190 citations

Regulation of Androgen Receptor Activity by the Nuclear Receptor Corepressor SMRT

2003 • 181 citations

Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen

1997 • 167 citations

Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function

2002 • 165 citations

Gene Silencing by Chicken Ovalbumin Upstream Promoter-Transcription Factor I (COUP-TFI) Is Mediated by Transcriptional Corepressors, Nuclear Receptor-Corepressor (N-CoR) and Silencing Mediator for Retinoic Acid Receptor and Thyroid Hormone Receptor (SMRT)

1997 • 162 citations

Recent advances in androgen receptor action

2003 • 158 citations

Androgen-induced recruitment of RNA polymerase II to a nuclear receptor–p160 coactivator complex

2003 • 154 citations

The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor

2004 • 153 citations

The Amino Terminus of the Human AR Is Target for Corepressor Action and Antihormone Agonism

2002 • 143 citations

The Androgen Receptor Recruits Nuclear Receptor CoRepressor (N-CoR) in the Presence of Mifepristone via Its N and C Termini Revealing a Novel Molecular Mechanism for Androgen Receptor Antagonists

2004 • 138 citations

Expression and function of androgen receptor coactivators in prostate cancer

2004 • 135 citations

Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

1997 • 134 citations

RU486-induced Glucocorticoid Receptor Agonism Is Controlled by the Receptor N Terminus and by Corepressor Binding

2002 • 133 citations

p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin

2000 • 126 citations

Minireview: Nuclear Receptor Coactivators--An Update

2002 • 118 citations

Androgen receptor corepressors: An overview

2004 • 117 citations

Inhibition of the Dihydrotestosterone-Activated Androgen Receptor by Nuclear Receptor Corepressor

2002 • 116 citations

Antiandrogen Effects of Mifepristone on Coactivator and Corepressor Interactions with the Androgen Receptor

2003 • 112 citations

Androgen Receptors in Prostate Cancer

2003 • 98 citations

Dehydroepiandrosterone Activates Mutant Androgen Receptors Expressed in the Androgen-Dependent Human Prostate Cancer Xenograft CWR22 and LNCaP Cells

1997 • 93 citations

Nuclear receptor‐dependent transcription with chromatin

2002 • 78 citations

Role of the androgen receptor axis in prostate cancer

2003 • 60 citations

Formation of the Androgen Receptor Transcription Complex

2003 • 54 citations

Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR)

2004 • 52 citations

Agonist–antagonist induced coactivator and corepressor interplay on the human androgen receptor

2003 • 44 citations

Gene Silencing by Chicken Ovalbumin Upstream Promoter-Transcription Factor I (COUP-TFI) Is Mediated by Transcriptional Corepressors, Nuclear Receptor-Corepressor (N-CoR) and Silencing Mediator for Retinoic Acid Receptor and Thyroid Hormone Receptor (SMRT)

1997 • 42 citations

Inhibition of the Dihydrotestosterone-Activated Androgen Receptor by Nuclear Receptor Corepressor

2002 • 36 citations

The Amino Terminus of the Human AR Is Target for Corepressor Action and Antihormone Agonism

2002 • 32 citations

Transcriptional repression by the thyroid hormone receptor: function of corepressor complexes

2004 • 3 citations