Differences in megakaryocyte expansion potential between CD34+ stem cells derived from cord blood, peripheral blood, and bone marrow from adults and children

Primitive Human Hematopoietic Cells Are Enriched in Cord Blood Compared With Adult Bone Marrow or Mobilized Peripheral Blood as Measured by the Quantitative In Vivo SCID-Repopulating Cell Assay

1997 • 488 citations

A functional comparison of CD34 + CD38- cells in cord blood and bone marrow

1995 • 456 citations

Placental and/or Umbilical Cord Blood: An Alternative Source of Hematopoietic Stem Cells for Transplantation

1997 • 402 citations

Allogeneic peripheral blood stem cell transplantation in patients with advanced hematologic malignancies: a retrospective comparison with marrow transplantation

1996 • 370 citations

The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors

1995 • 283 citations

Ability of Early Acting Cytokines to Directly Promote Survival and Suppress Apoptosis of Human Primitive CD34+CD38− Bone Marrow Cells With Multilineage Potential at the Single-Cell Level: Key Role of Thrombopoietin

1997 • 201 citations

Megakaryocytic Progenitors Can Be Generated Ex Vivo and Safely Administered to Autologous Peripheral Blood Progenitor Cell Transplant Recipients

1997 • 179 citations

Ability of Early Acting Cytokines to Directly Promote Survival and Suppress Apoptosis of Human Primitive CD34+CD38− Bone Marrow Cells With Multilineage Potential at the Single-Cell Level: Key Role of Thrombopoietin

1997 • 169 citations

Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation

1992 • 167 citations

Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha.

1997 • 149 citations

Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture

1995 • 131 citations

The role of megakaryocyte growth and development factor in terminal stages of thrombopoiesis

1996 • 103 citations

The value of flow cytometric analysis of platelet glycoprotein expression of CD34+ cells measured under conditions that prevent P- selectin-mediated binding of platelets

1995 • 88 citations

Thrombopoietin Requires Additional Megakaryocyte-Active Cytokines for Optimal Ex Vivo Expansion of Megakaryocyte Precursor Cells

1998 • 87 citations

Allogeneic blood stem cell transplantation in advanced hematologic cancers

1997 • 82 citations

A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation

2000 • 82 citations

Autologous blood stem cell (ABSCT) versus purged bone marrow transplantation (pABMT) in standard risk AML: influence of source and cell composition of the autograft on hemopoietic reconstitution and disease-free survival.

1991 • 81 citations

Outcome of Cord-Blood Transplantation From Related and Unrelated Donors

1998 • 77 citations

CD34++ CD38- and CD34+ CD38+ human hematopoietic progenitors from fetal liver, cord blood, and adult bone marrow respond differently to hematopoietic cytokines depending on the ontogenic source.

1998 • 65 citations

The Development of Human Megakaryocytes: III. Development of Mature Megakaryocytes From Highly Purified Committed Progenitors in Synthetic Culture Media and Inhibition of Thrombopoietin-Induced Polyploidization by Interleukin-3

1997 • 58 citations

Quantitation and characterization of human megakaryocyte colony‐forming cells using a standardized serum‐free agarose assay

1997 • 58 citations

Megakaryocyte--platelet axis and the process of platelet formation and release

1980 • 55 citations

Effects of thrombopoietin on the proliferation and differentiation of primitive and mature haemopoietic progenitor cells in cord blood

1998 • 52 citations

Phase 1 study of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients after autologous peripheral blood progenitor cell (PBPC) transplantation

2000 • 51 citations

CD34+/CD41a+ cells best predict platelet recovery after autologous peripheral blood stem cell transplantation

1998 • 50 citations

Proliferative properties of human umbilical cord blood megakaryocyte progenitor cells to human thrombopoietin.

1998 • 47 citations

Cord blood is better than bone marrow for generating megakaryocytic progenitor cells

1999 • 46 citations

Ex vivo expansion of megakaryocyte progenitors: effect of various growth factor combinations on CD34+ progenitor cells from bone marrow and G-CSF-mobilized peripheral blood.

1997 • 44 citations

Comparison of the coexpression of cd38, cd33 and hla‐dr antigens on cd34 ⁺ purified cells from human cord blood and bone marrow

1995 • 43 citations

A combination of megakaryocyte growth and development factor and interleukin‐1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes

1999 • 42 citations

Megakaryocyte--platelet axis and the process of platelet formation and release

1980 • 40 citations

Risks, Costs, and Alternatives to Platelet Transfusions

1999 • 38 citations

Hematopoietic stem‐cell transplantation using unrelated cord‐blood versus matched sibling marrow in pediatric bone marrow failure syndrome: One center’s experience

1999 • 35 citations

Effects of Recombinant Human Thrombopoietin Alone and in Combination with Erythropoietin and Early‐Acting Cytokines on Human Mobilized Purified CD34 ⁺ Progenitor Cells Cultured in Serum‐Depleted Medium

1997 • 34 citations

Ex vivo expansion of enriched CD34+ cells from neonatal blood in the presence of thrombopoietin, a comparison with cord blood and bone marrow

1999 • 31 citations

Platelet growth factors: potential impact on transfusion medicine

1999 • 24 citations

Complementary and antagonistic effects of IL‐3 in the early development of human megakaryocytes in culture

1998 • 19 citations

Megakaryocyte Ex Vivo Expansion Potential of Three Hematopoietic Sources in Serum and Serum-Free Medium

1999 • 16 citations

Ex-Vivo Expansion of Megakaryocyte Progenitors.

2004 • 11 citations

Deleted Work

1955 • 0 citations

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