The human interleukin-2 receptor β-chain gene: genomic organization, promoter analysis and chromosomal assignment

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

1985 • 1,207 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Interleukin-2 Receptor β Chain Gene: Generation of Three Receptor Forms by Cloned Human α and β Chain cDNA's

1989 • 680 citations

Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily

1990 • 614 citations

A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chain

1989 • 551 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering

1987 • 438 citations

Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

1987 • 423 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Kappa B-Specific DNA Binding Proteins: Role in the Regulation of Human Interleukin-2 Gene Expression

1989 • 327 citations

THE MULTI-SUBUNIT INTERLEUKIN-2 RECEPTOR

1989 • 323 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Regulation of Cytokine Gene Expression

1988 • 234 citations

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies.

1989 • 219 citations

Structure of the Human Interleukin-2 Receptor Gene

1985 • 219 citations

The Human Interleukin-2 Receptor

1986 • 209 citations

Erythropoietin receptor and interleukin-2 receptor β chain: A new receptor family

1989 • 208 citations

Transformation of NIH 3T3 cells by a human c-sis cDNA clone

1984 • 181 citations

A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor.

1987 • 174 citations

Reconstitution of functional receptor for human interleukin-2 in mouse cells

1985 • 150 citations

Characterization of Antigen Receptor Response Elements within the Interleukin-2 Enhancer

1988 • 143 citations

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.

1985 • 119 citations

A primary genetic map of markers for human chromosome 10

1988 • 95 citations

Expression of functional human interleukin-2 receptor in mouse T cells by cDNA transfection

1986 • 80 citations

pSV00CAT: low background CAT plasmid

1988 • 75 citations

Involvement of a common transcription factor in the regulated expression of IL-2 and IL-2 receptor genes

1989 • 60 citations

Molecular cloning and structure of the human interleukin 2 receptor gene

1985 • 59 citations

Identification of multiplecis-elements andtrans-acting factors involved in the induced expresson of human IL-2 gene

1989 • 39 citations

Properties of human interleukin-2 receptors expressed on non-lymphoid cells by cDNA transfection.

1984 • 37 citations

Human interleukin 2 (IL 2) receptor β chain allows transduction of IL 2-induced proliferation signal(s) in a murine cell line

1989 • 27 citations