Reconstitution of functional receptor for human interleukin-2 in mouse cells

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Transient expression of interleukin 2 receptors. Consequences for T cell growth.

1983 • 613 citations

Molecular cloning of cDNA encoding human interleukin-2 receptor

1984 • 567 citations

The Biochemistry, Biology, and Role of Interleukin 2 in the Induction of Cytotoxic T Cell and Antibody-Forming B Cell Responses

1982 • 524 citations

Interleukin 2

1984 • 497 citations

Interleukin 2 regulates its own receptors.

1985 • 414 citations

Immunoglobulin gene expression in transformed lymphoid cells.

1983 • 400 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter.

1979 • 382 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells, and on one of two types of helper T cells.

1981 • 350 citations

Molecular cloning of human interleukin 2 cDNA and its expression inE. coli

1983 • 307 citations

Cloning, sequence and expression of human interleukin-2 receptor

1984 • 272 citations

Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells.

1985 • 237 citations

Unique structure of murine interleukin-2 as deduced from cloned cDNAs

1985 • 205 citations

Structure of the human interleukin 2 gene.

1983 • 197 citations

Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.

1985 • 178 citations

SV40 DNA transfection of cells in suspension: analysis of the efficiency of transcription and translation of T-antigen

1981 • 161 citations

A rat monoclonal antibody that binds specifically to mouse T lymphoblasts and inhibits IL 2 receptor functions: a putative anti-IL 2 receptor antibody.

1984 • 121 citations

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.

1985 • 119 citations

T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells.

1984 • 113 citations

Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence

1985 • 96 citations

Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF

1982 • 95 citations

Organization and structure of the mouse interleukin-2 gene

1984 • 83 citations

Partial characterization of gamma (immune) interferon mRNA extracted from human lymphocytes.

1981 • 40 citations

Interleukin 2 inhibits in vitro growth of human T cell lines carrying retrovirus.

1985 • 37 citations