Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

1993 • 1,317 citations

The Primary Immunodeficiencies

1984 • 1,111 citations

A very high level of crossreactivity is an essential feature of the T-cell receptor

1998 • 930 citations

A Direct Estimate of the Human αβ T Cell Receptor Diversity

1999 • 893 citations

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments.

1993 • 664 citations

T-cell repertoire diversity and clonal expansions in normal and clinical samples

1995 • 562 citations

STRUCTURE AND FUNCTION OF THE PRE-T CELL RECEPTOR

1997 • 362 citations

Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: Application in the production of chimeric thymus rudiments

1982 • 324 citations

Designing and Maintaining the Mature TCR Repertoire

1999 • 323 citations

The Primary Immunodeficiencies

1995 • 311 citations

VDJ recombination

1992 • 307 citations

T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice

1994 • 305 citations

Atypical X-Linked Severe Combined Immunodeficiency Due to Possible Spontaneous Reversion of the Genetic Defect in T Cells

1996 • 276 citations

Bcl-2 Rescues T Lymphopoiesis, but Not B or NK Cell Development, in Common γ Chain–Deficient Mice

1997 • 220 citations

NATURALLY OCCURRING PRIMARY DEFICIENCIES OF THE IMMUNE SYSTEM

1997 • 159 citations

Natural and Engineered Disorders of Lymphocyte Development

1998 • 102 citations

A Molecular Map of T Cell Development

1998 • 94 citations

The Composition of a Primary T Cell Response Is Largely Determined by the Timing of Recruitment of Individual T Cell Clones

1999 • 86 citations

IL2RGbase: a database of γc-chain defects causing human X-SCID

1996 • 82 citations

Multiple γc-dependent cytokines regulate T-cell development

1999 • 66 citations

The Antigen t Cell Receptor: Selected Protocols and Applications

1997 • 56 citations

Development of T cell precursor activity in the murine fetal liver

1998 • 25 citations