Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice

Tumor spectrum analysis in p53-mutant mice

1994 • 2,034 citations

Effects of an Rb mutation in the mouse

1992 • 1,779 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1992 • 1,285 citations

Cell death by mitotic catastrophe: a molecular definition

2004 • 1,201 citations

Two genetic hits (more or less) to cancer

2001 • 1,108 citations

Requirement for a functional Rb-1 gene in murine development

1992 • 1,015 citations

Centromeres and Kinetochores

2003 • 967 citations

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

2001 • 727 citations

Aneuploidy and cancer

2004 • 710 citations

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

2004 • 702 citations

Stuck in Division or Passing through

2004 • 630 citations

Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B

2004 • 588 citations

The spindle checkpoint, aneuploidy, and cancer

2004 • 528 citations

Chromosome Missegregation and Apoptosis in Mice Lacking the Mitotic Checkpoint Protein Mad2

2000 • 523 citations

Timing and Checkpoints in the Regulation of Mitotic Progression

2004 • 468 citations

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

2003 • 336 citations

Slippage of Mitotic Arrest and Enhanced Tumor Development in Mice with BubR1 Haploinsufficiency

2004 • 290 citations

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

2000 • 249 citations

Structure, Function, and Regulation of Budding Yeast Kinetochores

2003 • 200 citations

Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells

2004 • 191 citations

BUBR1 deficiency results in abnormal megakaryopoiesis

2003 • 182 citations

Chromosome segregation and genomic stability

2004 • 169 citations

The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling

2002 • 77 citations

Analyzing the Spindle Checkpoint in Yeast and Frogs

2004 • 5 citations