Slippage of Mitotic Arrest and Enhanced Tumor Development in Mice with BubR1 Haploinsufficiency

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

2001 • 877 citations

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

2001 • 727 citations

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

2001 • 553 citations

The spindle checkpoint: structural insights into dynamic signalling

2002 • 526 citations

The significance of unstable chromosomes in colorectal cancer

2003 • 500 citations

Human Bubr1 Is a Mitotic Checkpoint Kinase That Monitors Cenp-E Functions at Kinetochores and Binds the Cyclosome/APC

1999 • 379 citations

Ataxia-telangiectasia and cellular responses to DNA damage.

1995 • 378 citations

Securin Is Required for Chromosomal Stability in Human Cells

2001 • 351 citations

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

2003 • 336 citations

Activating and Silencing the Mitotic Checkpoint through CENP-E-Dependent Activation/Inactivation of BubR1

2003 • 239 citations

BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1

2002 • 184 citations

BUBR1 deficiency results in abnormal megakaryopoiesis

2003 • 182 citations

Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon.

1993 • 181 citations

Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.

2002 • 178 citations

Mad2 and BubR1 Function in a Single Checkpoint Pathway that Responds to a Loss of Tension

2002 • 99 citations

A new view of the spindle checkpoint

2001 • 94 citations

BUBR1 phosphorylation is regulated during mitotic checkpoint activation.

1999 • 55 citations

Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas

2001 • 31 citations

The effect of promoters on 1,2-dimethylhydrazine-induced colon carcinogenesis.

1984 • 3 citations