Lifelong corticosterone level determines age-related decline in neurogenesis and memory

The Ki-67 protein: From the known and the unknown

2000 • 4,426 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

Cortisol levels during human aging predict hippocampal atrophy and memory deficits

1998 • 1,613 citations

Effect of Neonatal Handling on Age-Related Impairments Associated with the Hippocampus

1988 • 1,068 citations

Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus

2000 • 1,022 citations

Are New Neurons Formed in the Brains of Adult Mammals?

1962 • 930 citations

Neurogenesis in the adult brain: death of a dogma

2000 • 796 citations

Stress, the Aging Brain, and the Mechanisms of Neuron Death

1992 • 788 citations

Restoring production of hippocampal neurons in old age

1999 • 717 citations

Adrenal hormones suppress cell division in the adult rat dentate gyrus

1992 • 638 citations

Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis

2003 • 638 citations

Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats

1995 • 527 citations

Selective Loss of Hippocampal Granule Cells in the Mature Rat Brain After Adrenalectomy

1989 • 520 citations

Hippocampal Aging and Adrenocorticoids: Quantitative Correlations

1978 • 486 citations

The hippocampus and declarative memory: cognitive mechanisms and neural codes

2001 • 459 citations

Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis

2001 • 430 citations

Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats

1990 • 428 citations

Long‐term effects of prenatal stress and postnatal handling on age‐related glucocorticoid secretion and cognitive performance: a longitudinal study in the rat

1999 • 368 citations

An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses.

1985 • 334 citations

Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus–pituitary–adrenal axis activation

2003 • 311 citations

Individual differences in the cognitive and neurobiological consequences of normal aging

1992 • 287 citations

An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses.

1985 • 275 citations

Individual differences in aging: Behavioral and neurobiological correlates

1989 • 254 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Differential effects of learning on neurogenesis: learning increases or decreases the number of newly born cells depending on their birth date

2003 • 241 citations

Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats.

1986 • 231 citations

NMDA receptor antagonist treatment induces a long‐lasting increase in the number of proliferating cells, PSA‐NCAM‐immunoreactive granule neurons and radial glia in the adult rat dentate gyrus

2001 • 203 citations

NMDA receptor antagonist treatment increases the production of new neurons in the aged rat hippocampus

2002 • 182 citations

The effects of long-term corticosterone administration on hippocampal morphology and cognitive performance of middle-aged rats

1994 • 170 citations

Age pigments, cell loss and hippocampal function

1979 • 170 citations

Effect of Chronic High-Dose Exogenous Cortisol on Hippocampal Neuronal Number in Aged Nonhuman Primates

1999 • 151 citations

Markers for biogenic amines in the aged rat brain: Relationship to decline in spatial learning ability

1990 • 146 citations

Theta-Frequency Synaptic Potentiation in CA1In VitroDistinguishes Cognitively Impaired from Unimpaired Aged Fischer 344 Rats

2002 • 145 citations

Hippocampal neurobiological mechanisms of age-related memory dysfunction

1988 • 138 citations

Adrenalectomy increases neurogenesis but not PSA‐NCAM expression in aged dentate gyrus

1999 • 135 citations

Distinct populations of cells in the adult dentate gyrus undergo mitosis or apoptosis in response to adrenalectomy

1996 • 117 citations

Chronic Treatment with the Antidepressant Amitriptyline Prevents Impairments in Water Maze Learning in Aging Rats

2002 • 106 citations

Maintenance of Hippocampal Cell Numbers in Young and Aged Rats Submitted to Chronic Unpredictable Stress. Comparison with the Effects of Corticosterone Treatment

1998 • 106 citations

Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus

1991 • 101 citations

Implication of corticosteroid receptors in the regulation of hippocampal structural plasticity

2003 • 82 citations

Adrenalectomy-induced apoptosis and glial responsiveness during ageing

1998 • 20 citations

Corticotropin Releasing Hormone Antagonist Does Not Prevent Adrenalectomy-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus

1998 • 9 citations