Individual differences in aging: Behavioral and neurobiological correlates

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

1979 • 1,970 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities

1969 • 1,043 citations

Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa

1980 • 866 citations

Excitatory amino acids in the brain - focus on NMDA receptors

1987 • 641 citations

Spatial learning and motor deficits in aged rats

1984 • 509 citations

Spatial memory deficit in senescent rats.

1980 • 479 citations

Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions

1985 • 419 citations

Intrahippocampal Septal Grafts Ameliorate Learning Impairments in Aged Rats

1984 • 369 citations

An evaluation of spatial information processing in aged rats.

1987 • 353 citations

Age-Related Changes in Passive Avoidance Retention: Modulation with Dietary Choline

1980 • 271 citations

Regulation of Acetylcholine Synthesis in the Brain

1985 • 268 citations

Changes in Nicotinic and Muscarinic Cholinergic Receptors in Alzheimer‐Type Dementia

1986 • 261 citations

Brain cholinergic dysfunction and memory in aged rats

1980 • 257 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Presynaptic Nicotinic Cholinergic Receptors Labeled by [³H]Acetylcholine on Catecholamine and Serotonin Axons in Brain

1984 • 235 citations

Animal Models of Declining Memory in the Aged: Short-term and Spatial Memory in the Aged Rat

1980 • 227 citations

Age-related behavioral and neurobiological changes: A review with an emphasis on memory

1981 • 222 citations

Age-related changes in multiple neurotransmitter systems in the monkey brain

1989 • 222 citations

Aging and the physiology of spatial memory

1988 • 217 citations

Age and neurochemical correlates of radial maze performance in rats

1981 • 217 citations

Daytime sleepiness: Quantification of a behavioral state

1987 • 174 citations

Memory Deficits in Aged Cebus Monkeys and Facilitation With Central Cholinomimetics

1980 • 170 citations

Aged rats need a preserved complement of perforated axospinous synapses per hippocampal neuron to maintain good spatial memory

1986 • 149 citations

Neurotransmitters and memory: Role of cholinergic, serotonergic, and noradrenergic systems.

1987 • 142 citations

EFFECTS OF AGEING ON LOCAL RATES OF CEREBRAL GLUCOSE UTILIZATION IN THE RAT

1980 • 139 citations

Rapid forgetting in aged rats

1982 • 130 citations

Characterization of Two [³H]Glutamate Binding Sites in Rat Hippocampal Membranes

1981 • 128 citations

Memory dysfunctions: an integration of animal and human research from preclinical and clinical perspectives.

1985 • 123 citations

Neurotransmitters and memory: Role of cholinergic, serotonergic, and noradrenergic systems.

1987 • 118 citations

Performance During Frequent Sleep Disruption

1987 • 109 citations

Analysis of Age‐Related Impairments in Learning and Memory in Rodent Models

1985 • 103 citations

Age-related changes in the sleep pattern of male adult rats

1983 • 98 citations

Noradrenergic changes and memory loss in aged mice

1985 • 97 citations

Sleep in Young and Old Rats

1979 • 93 citations

Electrophysiological Markers of Aging and Memory Loss in Rats^a

1985 • 81 citations

Age dependent changes in retention in rats I

1982 • 74 citations

Age-related memory deficits in rats and mice: Enhancement with peripheral injections of epinephrine

1985 • 69 citations

The organization and regulation of sleep

1984 • 68 citations

Discrimination learning requiring different memory components in rats: Age and neurochemical comparisons.

1985 • 60 citations

Correlation of behavioral and cerebrovascular functions in the aging rat

1987 • 60 citations

Aging and sleep in the albino rat

1972 • 59 citations

Discrimination learning requiring different memory components in rats: Age and neurochemical comparisons.

1985 • 51 citations

Aged rats: diminished sympathetic—adrenal medullary responses to acute stress

1981 • 48 citations

Amygdala kindling effects on sleep and memory in rats

1988 • 39 citations

Spatial memory and visual evoked potentials in young and old rats after housing in an enriched environment

1985 • 38 citations

Age, Learning, Ability, and Intelligence

1981 • 37 citations

Age differences in within-session habituation of exploratory behavior: effects of stimulus complexity

1984 • 37 citations

Association of sleep parameters and memory in intact old rats and young rats with lesions in the nucleus basalis magnocellularis.

1989 • 35 citations

Memory of simple learning in young, middle-aged, and aged C57/BL6 mice

1981 • 31 citations

Within-subjects, parametric manipulations to investigate aging

1988 • 28 citations

Learning and memory in young and aged Fischer 344 rats

1983 • 23 citations

Age-dependent correlation of motor performance with neurotransmitter synthetic enzyme activities in mice

1983 • 19 citations

Age-related changes in brain catecholamine responses to a single footshock

1984 • 18 citations

Sensory Systems and Communications in the Elderly.

1980 • 11 citations

Effects of Prenatal Phenobarbital on Benzodiazepine Receptor Development

1986 • 6 citations