Maintenance of Hippocampal Cell Numbers in Young and Aged Rats Submitted to Chronic Unpredictable Stress. Comparison with the Effects of Corticosterone Treatment

The efficiency of systematic sampling in stereology and its prediction*

1987 • 3,508 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1991 • 2,982 citations

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis

1988 • 2,948 citations

The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

1988 • 2,498 citations

Neurocircuitry of stress: central control of the hypothalamo–pituitary–adrenocortical axis

1997 • 2,235 citations

Stress and cognitive function

1995 • 1,830 citations

The Role of the Hippocampus in Feedback Regulation of the Hypothalamic-Pituitary-Adrenocortical Axis*

1991 • 1,690 citations

Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

1992 • 1,215 citations

Unbiased stereological estimation of the number of neurons in the human hippocampus

1990 • 1,146 citations

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

1985 • 1,129 citations

The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress

1993 • 1,118 citations

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons

1990 • 1,013 citations

Methods for determining numbers of cells and synapses: A case for more uniform standards of review

1996 • 981 citations

Brain corticosteroid receptor balance and homeostatic control

1991 • 858 citations

Antidepressants and Hypothalamic-Pituitary-Adrenocortical Regulation

1996 • 829 citations

Hippocampal damage associated with prolonged and fatal stress in primates

1989 • 746 citations

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion

1996 • 737 citations

Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response.

1984 • 729 citations

Anatomical specificity of noradrenergic inputs to the paraventricular and supraoptic nuclei of the rat hypothalamus

1988 • 715 citations

Inverted‐U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation

1992 • 671 citations

Variations in the Hypothalamic-Pituitary-Adrenal Response to Stress during the Estrous Cycle in the Rat

1991 • 664 citations

Preserved neuron number in the hippocampus of aged rats with spatial learning deficits.

1996 • 635 citations

Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system

1993 • 577 citations

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Comparison of stressors

1995 • 566 citations

Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats

1995 • 527 citations

Behavioral stress impairs long-term potentiation in rodent hippocampus

1987 • 441 citations

Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats

1990 • 428 citations

Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats

1973 • 406 citations

Control of neuronal excitability by corticosteroid hormones

1992 • 399 citations

Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression

1995 • 398 citations

Organization of adrenergic inputs to the paraventricular and supraoptic nuclei of the hypothalamus in the rat

1990 • 322 citations

Effects of glucocorticoids on hippocampal long‐term potentiation

1993 • 320 citations

Frontiers in Neuroendocrinology, 1973.

1973 • 302 citations

The adrenocorticol stress-response in the aged male rat: Impairment of recovery from stress

1983 • 288 citations

Neuropsychiatric Manifestations of Patients With Cushing's Syndrome

1981 • 276 citations

Chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging

1991 • 255 citations

Steroids and Apparent Cerebral Atrophy on Computed Tomography Scans

1978 • 246 citations

Stress induces neuronal death in the hippocampus of castrated rats

1992 • 206 citations

Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats

1994 • 185 citations

Exacerbation of Apoptosis in the Dentate Gyrus of the Aged Rat by Dexamethasone and the Protective Role of Corticosterone

1996 • 177 citations

The effects of long-term corticosterone administration on hippocampal morphology and cognitive performance of middle-aged rats

1994 • 170 citations

Glucocorticoid Implants around the Hypothalamic Paraventricular Nucleus Prevent the Increase of Corticotropin-Releasing Factor and Arginine Vasopressin Immunostaining Induced by Adrenalectomy

1986 • 164 citations

Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons—a quantitative study

1995 • 149 citations

Suprachiasmatic nucleus lesion increases corticosterone secretion

1993 • 147 citations

Increased Cortisol Levels in Aging and Alzheimer's Disease in Postmortem Cerebrospinal Fluid

1994 • 138 citations

Age and sex do not affect the volume, cell numbers, or cell size of the suprachiasmatic nucleus of the rat: An unbiased stereological study

1995 • 124 citations

Cerebral Atrophy Following ACTH Therapy

1980 • 103 citations

Serum corticosterone level predicts the magnitude of hippocampal primed burst potentiation and depression in urethane-anesthetized rats

1991 • 103 citations

Neurochemical, endocrine and immunological responses to stress in young and old Fischer 344 male rats

1990 • 90 citations

Effect of Stress, Adrenalectomy, Hypophysectomy and Hydrocortisone on the Corticotropin-Releasing Activity of Rat Median Eminence

1965 • 78 citations

Anabolic-androgenic steroid and adrenal steroid effects on hippocampal plasticity

1995 • 68 citations

The glucocorticoid hypothesis of brain aging and neurodegeneration: recent modifications.

1991 • 55 citations

Comments on review by coleman and flood ‘neuron numbers and dendritic extent in normal aging and alzheimer's disease.’ density measures: Parameters to avoid

1987 • 49 citations

Lesions of the Hippocampal Efferent Pathway (Fimbria-Fornix) Do Not Alter Sensitivity of Adrenocorticotropin to Feedback Inhibition by Corticosterone in Rats

1993 • 47 citations

Ventromedial Hypothalamic Lesions Inhibit Corticosteroid Feedback Regulation of Basal ACTH during the Trough of the Circadian Rhythm

1995 • 46 citations

Regulation of the hypothalamo-pituitary-adrenal axis during stress: feedback, facilitation and feeding

1994 • 45 citations

Structural alterations of the hippocampal formation of adrenalectomized rats: an unbiased stereological study.

1997 • 44 citations

Aging, Stress, and Cognitive Function^a

1994 • 43 citations

Neonatal monosodium glutamate treatment alters both the activity and the sensitivity of the rat hypothalamo-pituitary-adrenocortical axis

1994 • 43 citations

Changes of plasma and adrenal catecholamines and corticosterone in stressed rats with septal lesions

1982 • 36 citations

The Role of Limbic Structures in the Modulation of ACTH Responses following Adrenalectomya

1995 • 25 citations

Brain growth: Interactions of maturation with adrenal steroids

1983 • 22 citations

Regulation of plasma catecholamine responses to stress

1994 • 20 citations

Adrenal modulation of brain size in adult rats

1979 • 17 citations