Soluble HLA‐A,‐B,‐C and ‐G molecules induce apoptosis in T and NK CD8⁺ cells and inhibit cytotoxic T cell activity through CD8 ligation

Separation of leukocytes from blood and bone marrow

1968 • 2,787 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens.

1992 • 515 citations

Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules

1981 • 511 citations

Cutting Edge: Soluble HLA-G1 Triggers CD95/CD95 Ligand-Mediated Apoptosis in Activated CD8+ Cells by Interacting with CD8

2000 • 465 citations

A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4.

1994 • 365 citations

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1995 • 320 citations

Soluble HLA-G protein secreted by allo-specific CD4⁺T cells suppresses the allo-proliferative response: A CD4⁺T cell regulatory mechanism

2001 • 316 citations

Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

1996 • 274 citations

Anti HL-A2 Inhibitor in Normal Human Serum

1970 • 216 citations

Detection of soluble HLA‐G molecules in plasma and amniotic fluid

1999 • 186 citations

Soluble HLA-G circulates in maternal blood during pregnancy

2000 • 180 citations

Structure and function of the human MHC class Ib molecules HLA‐E, HLA‐F and HLA‐G

1998 • 173 citations

Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-? immunotherapy

2001 • 165 citations

Soluble HL-A7 Antigen: Localization in the β-Lipoprotein Fraction of Human Serum

1970 • 156 citations

A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.

1993 • 144 citations

Structural and functional analysis of monomorphic determinants recognized by monoclonal antibodies reacting with the HLA class I alpha 3 domain.

1992 • 137 citations

Serum HLA class I antigens: markers and modulators of an immune response?

1995 • 121 citations

Soluble HLA levels in early pregnancy after in vitro fertilization

2000 • 120 citations

HETEROGENEOUS DISTRIBUTION OF THE DETERMINANTS DEFINED BY MONOCLONAL ANTIBODIES ON HLA-A AND B ANTIGENS BEARING MOLECULES

1982 • 111 citations

Recognition of the Epstein-Barr virus-encoded nuclear antigens EBNA-4 and EBNA-6 by HLA-A11-restricted cytotoxic T lymphocytes: implications for down-regulation of HLA-A11 in Burkitt lymphoma.

1992 • 110 citations

Soluble human MHC class I molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8+ Fas (CD95)+ T lymphocytes

2000 • 109 citations

Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily

2002 • 80 citations

A Novel Approach to Antigen-Specific Deletion of CTL with Minimal Cellular Activation Using α3 Domain Mutants of MHC Class I/Peptide Complex

2001 • 77 citations

Interaction of papain-digested HLA class I molecules with human alloreactive cytotoxic T lymphocytes (CTL)

1993 • 69 citations

Elevated serum level of soluble HLA class I antigens in patients with systemic lupus erythematosus

1996 • 47 citations

Soluble HLA antigens: new roles and uses

1997 • 41 citations

Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction

2000 • 29 citations

LIVER TRANSPLANT RECIPIENT SERA DERIVED SOLUBLE HLA MEDIATES ALLELE SPECIFIC CTL APOPTOSIS

2000 • 21 citations

PURIFIED TRUNCATED RECOMBINANT HLA-B7 MOLECULES ABROGATE CELL FUNCTION IN ALLOREACTIVE CYTOTOXIC T LYMPHOCYTES BY APOPTOSIS INDUCTION1,2

1998 • 11 citations