Transforming growth factor‐β1 as a useful serologic marker of small hepatocellular carcinoma

A method of comparing the areas under receiver operating characteristic curves derived from the same cases.

1983 • 6,923 citations

Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine

1993 • 6,407 citations

Role of Transforming Growth Factor β in Human Disease

2000 • 2,405 citations

Risk Factors for Hepatocellular Carcinoma among Patients with Chronic Liver Disease

1993 • 1,118 citations

Surgical resection of hepatocellular carcinoma in cirrhotic patients: Prognostic value of preoperative portal pressure

1996 • 874 citations

Hepatocellular Carcinoma in Italian Patients with Cirrhosis

1991 • 832 citations

Selection and interpretation of diagnostic tests and procedures

1981 • 605 citations

Early detection of hepatocellular carcinoma increases the chance of treatment: Hong Kong experience

2000 • 417 citations

Prospective study of early detection of hepatocellular carcinoma in patients with cirrhosis

1990 • 405 citations

Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis

1986 • 404 citations

α-fetoprotein: Reevaluation in hepatology

1990 • 350 citations

Physicochemical Activation of Recombinant Latent Transforming Growth Factor-beta's 1, 2, and 3

1990 • 343 citations

Screening for Hepatocellular Carcinoma in Alaska Natives Infected With Chronic Hepatitis B: A 16-Year Population-Based Study

2000 • 331 citations

Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis

1986 • 317 citations

A collaborative study for the evaluation of lectin-reactive alpha-fetoproteins in early detection of hepatocellular carcinoma.

1993 • 285 citations

Cirrhosis: diagnosis with sonographic study of the liver surface.

1989 • 277 citations

Diagnosis and clinical features of small hepatocellular carcinoma with emphasis on the utility of real-time ultrasonography. A study in 51 patients.

1984 • 268 citations

Diagnosis and Clinical Features of Small Hepatocellular Carcinoma With Emphasis on the Utility of Real-Time Ultrasonography

1984 • 235 citations

Transforming growth factor—beta 1 (TGF-β1) and TGF-β1 receptors in normal, cirrhotic, and neoplastic human livers

1995 • 219 citations

Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins.

1991 • 216 citations

Plasma transforming growth factor-β1 in patients with hepatocellular carcinoma. Comparison with chronic liver diseases

1994 • 215 citations

Serum alpha-fetoprotein in the early stage of human hepatocellular carcinoma.

1984 • 199 citations

A clinical study of lectin-reactive alpha-fetoprotein as an early indicator of hepatocellular carcinoma in the follow-up of cirrhotic patients

1995 • 176 citations

Elevations in serum alpha-fetoprotein levels in patients with chronic hepatitis B

1989 • 169 citations

Serum α-Fetoprotein in the Early Stage of Human Hepatocellular Carcinoma

1984 • 165 citations

Serum alphafetoprotein in hepatocellular carcinoma

1977 • 153 citations

Elevated levels of transforming growth factor beta messenger RNA and its polypeptide in human hepatocellular carcinoma.

1991 • 150 citations

Expression of transforming growth factor alpha in normal human adult kidney and enhanced expression of transforming growth factors alpha and beta 1 in renal cell carcinoma.

1989 • 143 citations

Type beta transforming growth factor from feline sarcoma virus-transformed rat cells. Isolation and biological properties.

1984 • 143 citations

Des-γ-carboxy (abnormal) prothrombin and hepatocellular carcinoma: A critical review

1993 • 141 citations

Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma

1999 • 134 citations

Small Hepatocellular Carcinoma—A Clinicopathological Study in Thirteen Patients

1982 • 131 citations

Transcripts for transforming growth factors in human breast cancer: clinical correlates

1990 • 107 citations

Specificities of serum α-fetoprotein in HBsAg+ and HBsAg− patients in the diagnosis of hepatocellular carcinoma

1991 • 102 citations

Expression of TGF‐β and procollagen type I and type III in human gastric carcinomas

1989 • 99 citations

Constitutive expression of mature transforming growth factor beta1 in the liver accelerates hepatocarcinogenesis in transgenic mice.

1997 • 91 citations

The detection of alpha 1-fetoprotein in patients with viral hepatitis.

1974 • 72 citations

CIRCULATING TRANSFORMING GROWTH FACTOR β1AS AN INDICATOR OF HEPATIC FUNCTION IMPAIRMENT IN LIVER CIRRHOSIS

2000 • 64 citations

Serum alpha-fetoprotein and lens culinaris agglutinin-reactive fraction of alpha-fetoprotein in patients with hepatocellular carcinoma

1993 • 46 citations

Clinical evaluation of urinary transforming growth factor-beta1 and serum alpha-fetoprotein as tumour markers of hepatocellular carcinoma

1997 • 43 citations

Transforming growth factor β1 differentially regulates α-fetoprotein and albumin in HuH-7 human hepatoma cells

1991 • 31 citations

Expression of Transforming Growth Factor beta - 1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection

2000 • 23 citations

Posttranscriptional regulation of albumin and alpha-fetoprotein messenger RNA by transforming growth factor-beta 1 requires de novo RNA and protein synthesis.

1992 • 17 citations

The diagnostic value of the assay of des-γ-carboxy prothrombin in the detection of small hepatocellular carcinoma

1991 • 13 citations

Posttranscriptional regulation of albumin and alpha-fetoprotein messenger RNA by transforming growth factor-beta 1 requires de novo RNA and protein synthesis

1992 • 7 citations