NLRX1 is a regulator of mitochondrial antiviral immunity

The plant immune system

2006 • 11,424 citations

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

2004 • 3,745 citations

Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

2005 • 3,059 citations

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

2005 • 2,449 citations

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

2005 • 2,312 citations

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

1999 • 2,159 citations

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1999 • 2,157 citations

VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling

2005 • 1,761 citations

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

2003 • 1,651 citations

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

2003 • 1,625 citations

Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

2003 • 1,527 citations

Large-scale analysis of the human and mouse transcriptomes

2002 • 1,493 citations

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

2006 • 1,130 citations

NODs: intracellular proteins involved in inflammation and apoptosis

2003 • 1,041 citations

NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease

2005 • 970 citations

Plant NBS-LRR proteins in pathogen sensing and host defense

2006 • 699 citations

NLRs join TLRs as innate sensors of pathogens

2005 • 663 citations

The Specific and Essential Role of MAVS in Antiviral Innate Immune Responses

2006 • 588 citations

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

2007 • 445 citations

Toll-Like Receptors and RNA Helicases: Two Parallel Ways to Trigger Antiviral Responses

2006 • 372 citations

CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases

2004 • 351 citations

Cutting Edge: CATERPILLER: A Large Family of Mammalian Genes Containing CARD, Pyrin, Nucleotide-Binding, and Leucine-Rich Repeat Domains

2002 • 311 citations

The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals

2005 • 211 citations

PAN1/NALP2/PYPAF2, an Inducible Inflammatory Mediator That Regulates NF-κB and Caspase-1 Activation in Macrophages

2004 • 154 citations

Plant Defense

2003 • 46 citations