Modulation of the Helicase Activity of eIF4A by eIF4B, eIF4H, and eIF4F

Initiation of translation in prokaryotes and eukaryotes

1999 • 1,379 citations

Translational control of gene expression

2000 • 1,371 citations

Translational control of gene expression

2001 • 1,192 citations

Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability

1996 • 829 citations

Crystal Structures of Complexes of PcrA DNA Helicase with a DNA Substrate Indicate an Inchworm Mechanism

1999 • 793 citations

Thermodynamic Parameters To Predict Stability of RNA/DNA Hybrid Duplexes

1995 • 672 citations

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

1997 • 660 citations

RNA Structure Prediction

1988 • 654 citations

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.

1990 • 632 citations

Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs.

1989 • 618 citations

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding

1998 • 613 citations

Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families

1999 • 530 citations

Major Domain Swiveling Revealed by the Crystal Structures of Complexes of E. coli Rep Helicase Bound to Single-Stranded DNA and ADP

1997 • 490 citations

Canonical Eukaryotic Initiation Factors Determine Initiation of Translation by Internal Ribosomal Entry

1996 • 484 citations

Translational control

1991 • 464 citations

Structure of the hepatitis C virus RNA helicase domain

1997 • 444 citations

New initiation factor activity required for globin mRNA translation.

1983 • 416 citations

Biochemical and Kinetic Characterization of the RNA Helicase Activity of Eukaryotic Initiation Factor 4A

1999 • 326 citations

Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase

2000 • 291 citations

Kinetic Measurement of the Step Size of DNA Unwinding by Escherichia coli UvrD Helicase

1997 • 249 citations

The Protein Family of RNA Helicases

1998 • 243 citations

Demonstration of Unidirectional Single-Stranded DNA Translocation by PcrA Helicase: Measurement of Step Size and Translocation Speed

1999 • 217 citations

RNA-stimulated ATPase activity of eukaryotic initiation factors.

1984 • 211 citations

The ATP-dependent interaction of eukaryotic initiation factors with mRNA.

1987 • 209 citations

The DEAD Box Protein eIF4A. 1. A Minimal Kinetic and Thermodynamic Framework Reveals Coupled Binding of RNA and Nucleotide

1998 • 204 citations

The DExH protein NPH-II is a processive and directional motor for unwinding RNA

2000 • 203 citations

TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

1993 • 186 citations

A Region Rich in Aspartic Acid, Arginine, Tyrosine, and Glycine (DRYG) Mediates Eukaryotic Initiation Factor 4B (eIF4B) Self-Association and Interaction with eIF3

1996 • 184 citations

Second Generation of Antisense Oligonucleotides: From Nuclease Resistance to Biological Efficacy in Animals

1996 • 168 citations

Therapeutic Applications Of Oligonucleotides

1992 • 158 citations

The DEAD Box Protein eIF4A. 2. A Cycle of Nucleotide and RNA-Dependent Conformational Changes

1998 • 156 citations

Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism

2000 • 148 citations

Further Characterization of the Helicase Activity of eIF4A

2001 • 135 citations

Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae – the prototype of the DEAD box protein family

1999 • 116 citations

Purification and Characterization of a New Eukaryotic Protein Translation Factor

1998 • 114 citations

The Translation Initiation Factor eIF-4B Contains an RNA-Binding Region That Is Distinct and Independent from its Ribonucleoprotein Consensus Sequence

1994 • 108 citations

Second-generation antisense oligonucleotides: structure—activity relationships and the design of improved signal-transduction inhibitors

1996 • 105 citations

Probing the function of the eucaryotic 5′ cap structure by using a monoclonal antibody directed against cap-binding proteins

1981 • 105 citations

[8] Purification of protein synthesis initiation factors from rabbit reticulocytes

1979 • 96 citations

Dissociation of double stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay

1989 • 88 citations

Biochemical evidence supporting a mechanism for cap-independent and internal initiation of eukaryotic mRNA.

1988 • 83 citations

Further Biochemical and Kinetic Characterization of Human Eukaryotic Initiation Factor 4H

1999 • 80 citations

Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase

1999 • 74 citations

Two structural domains of initiation factor eIF-4B are involved in binding to RNA.

1994 • 73 citations

Wheat Germ Translation Initiation Factor eIF4B Affects eIF4A and eIFiso4F Helicase Activity by Increasing the ATP Binding Affinity of eIF4A

2000 • 67 citations

Initiation factors that bind mRNA. A comparison of mammalian factors with wheat germ factors.

1988 • 57 citations

Kinetics of Escherichia coli helicase II-catalyzed unwinding of fully duplex and nicked circular DNA

1993 • 19 citations

Kinetic Mechanism for the Sequential Binding of Two Single-Stranded Oligodeoxynucleotides to theEscherichia coliRep Helicase Dimer

1998 • 17 citations

Assays for Eukaryotic Translation Factors That Bind mRNA

1997 • 15 citations