Measurement of homocyst(e)ine in the prediction of arteriosclerosis

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

1992 • 2,655 citations

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

The pathogenesis of coronary artery disease and the acute coronary syndromes (First of two parts)

1992 • 1,958 citations

Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population

1993 • 1,920 citations

Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

1969 • 1,846 citations

A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians

1992 • 1,686 citations

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1985 • 1,251 citations

Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection

1987 • 1,072 citations

Disorders of transsulfuration

1989 • 1,053 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1985 • 739 citations

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

1991 • 702 citations

Homocystinemia

1974 • 655 citations

Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy.

1989 • 615 citations

Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

1991 • 615 citations

The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine

1992 • 562 citations

The pathogenesis of coronary artery disease. A possible role for methionine metabolism.

1976 • 535 citations

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.

1989 • 510 citations

Homocysteine and other thiols in plasma and urine: automated determination and sample stability

1993 • 480 citations

Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.

1988 • 479 citations

Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study.

1993 • 460 citations

Homocysteinemia due to folate deficiency

1987 • 423 citations

Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells

1990 • 392 citations

Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

1986 • 390 citations

Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease

1994 • 386 citations

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

1993 • 386 citations

High Performance Liquid Chromatography Method for Rapid and Accurate Determination of Homocysteine in Plasma and Serum

1991 • 345 citations

A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians

1992 • 329 citations

Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor.

1993 • 320 citations

Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells.

1993 • 314 citations

Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke.

1990 • 311 citations

Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease.

1986 • 307 citations

Plasma homocyst(e)ine levels in men with premature coronary artery disease

1990 • 304 citations

Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular disease.

1984 • 290 citations

Hyperhomocyst(e)inemia. A common and easily reversible risk factor for occlusive atherosclerosis.

1990 • 266 citations

Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors

1992 • 261 citations

Homocystinuria

1965 • 246 citations

Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons.

1983 • 241 citations

Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease.

1993 • 230 citations

Disordered methionine/homocysteine metabolism in premature vascular disease. Its occurrence, cofactor therapy, and enzymology.

1993 • 208 citations

Homocysteine and myocardial infarction

1988 • 197 citations

Treatment of mild hyperhomocysteinemia in vascular disease patients.

1994 • 186 citations

Effects of age, lipoproteins, and hemostatic parameters on the role of homocyst(e)inemia as a cardiovascular risk factor in men.

1994 • 150 citations

Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease.

1991 • 147 citations

Methionine intolerance: A possible risk factor for coronary artery disease

1985 • 144 citations

Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria

1983 • 138 citations

Homocyst(e)inemia in daily practice

1990 • 135 citations

Hyperhomocyst(e)inaemia: an independent risk factor for intermittent claudication

1992 • 128 citations

Modification of a high-performance liquid chromatographic method for assay of homocysteine in human plasma

1993 • 86 citations

Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation.

1984 • 85 citations

Cloning and screening with nanogram amounts of immunopurified mRNAs: cDNA cloning and chromosomal mapping of cystathionine beta-synthase and the beta subunit of propionyl-CoA carboxylase.

1986 • 74 citations

Homocyst(e)ine Accumulation in Pigs Fed Diets Deficient in Vitamin B-6: Relationship to Atherosclerosis

1983 • 67 citations

Hyperhomocyst(e)inemia in Utah siblings with early coronary disease

1990 • 51 citations

Fluorometric assay of thiols with fluorobenzoxadiazoles

1987 • 45 citations

Homocyst(e)ine and coronary artery disease

1992 • 43 citations

Detection of heterozygotes for recessive alleles. Homocyst(e)inemia: Paradigm of Pitfalls in phenotypes

1990 • 36 citations

High-performance liquid chromatography-fluorometry for the determination of thiols in biological samples using N-4-(6-dimethylamino-2-benzofuranyl)phenyl]-maleimide

1987 • 35 citations

Low vitamin B6 in patients with acute myocardial infarction

1989 • 33 citations

Determination of Plasma Homocysteine by HPLC with Fluorescence Detection: A Survey of Current Methods

1993 • 13 citations