Renal complications of nonsteroidal anti-inflammatory drugs

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1990 • 1,896 citations

Leukotrienes and Other Products of the 5-Lipoxygenase Pathway

1990 • 1,216 citations

Renal Syndromes Associated with Nonsteroidal Antiinflammatory Drugs

1984 • 1,098 citations

The eicosanoids and their biochemical mechanisms of action

1989 • 882 citations

Nonsteroidal Antiinflammatory Drugs — Differences and Similarities

1991 • 756 citations

Deciding who gets what.

1983 • 561 citations

Prostanoid biosynthesis and mechanisms of action

1992 • 551 citations

Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors.

1992 • 510 citations

Effects of Sulindac and Ibuprofen in Patients with Chronic Glomerular Disease

1984 • 334 citations

The clinical significance of inhibition of renal prostaglandin synthesis

1987 • 299 citations

Prostaglandins: Modulators of Renal Function and Pressor Resistance in Chronic Liver Disease*

1979 • 288 citations

Role of reactive oxygen metabolites in experimental glomerular disease

1989 • 276 citations

Segmental synthesis and actions of prostaglandins along the nephron

1987 • 256 citations

Analgesic Use and Chronic Renal Disease

1989 • 251 citations

Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function

1985 • 235 citations

Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in renal cortex

1978 • 232 citations

Modulation of angiotensin II-induced vasoconstriction by endothelium-derived relaxing factor in the isolated microperfused rabbit afferent arteriole.

1991 • 211 citations

Renal Effects of Ibuprofen, Piroxicam, and Sulindac in Patients with Asymptomatic Renal Failure

1990 • 203 citations

Effects of caloric restriction and weight loss on glycemic control, insulin release and resistance, and atherosclerotic risk in obese patients with type II diabetes mellitus

1984 • 187 citations

Indomethacin-Induced Prostaglandin Inhibition with Hyperkalemia

1979 • 185 citations

Attenuation of hypotensive effect of propranolol and thiazide diuretics by indomethacin.

1980 • 184 citations

Renal microvascular effects of vasopressin and vasopressin antagonists

1989 • 181 citations

Hyperkalemia in azotemic patients during angiotensin-converting enzyme inhibition and aldosterone reduction with captopril

1982 • 169 citations

Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A

1986 • 169 citations

Identification of Risk for Renal Insufficiency From Nonsteroidal Anti-inflammatory Drugs

1983 • 161 citations

Prostaglandin synthesis inhibition and the action of vasopressin: studies in man and rat

1977 • 156 citations

Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor.

1989 • 153 citations

Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-gamma, tumor necrosis factor-alpha, IgG aggregates, and cAMP in mouse mesangial cells.

1993 • 147 citations

Prevention of Acute Graft Rejection by the Prostaglandin E₁Analogue Misoprostol in Renal-Transplant Recipients Treated with Cyclosporine and Prednisone

1990 • 147 citations

Ibuprofen Interferes with the Efficacy of Antihypertensive Drugs

1987 • 140 citations

Reversible Acute Renal Failure from Combined Triamterene and Indomethacin

1982 • 139 citations

Fenoprofen nephropathy: Lipoid nephrosis and interstitial nephritis

1982 • 132 citations

NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND RENAL FAILURE

1986 • 131 citations

Nonsteroidal Anti-inflammatory Drug—Associated Azotemia in the Very Old

1990 • 126 citations

Glomerular and Interstitial Disease Induced by Nonsteroidal Anti-Inflammatory Drugs

1984 • 118 citations

Renal prostaglandin synthesis: Sites of production and specific actions of prostaglandins

1986 • 118 citations

Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men

1985 • 110 citations

Sulindac. A potentially renal-sparing nonsteroidal anti-inflammatory drug

1982 • 107 citations

Nonsteroidal Anti-inflammatory Drug Nephrotoxicity

1990 • 101 citations

Processing and presentation of self and foreign antigens by the renal proximal tubule.

1992 • 99 citations

Effects of prostaglandins on vasoconstrictor action in isolated renal arterioles

1985 • 93 citations

Prostaglandins and nonsteroidal anti-inflammatory drugs: Effects on renal hemodynamics

1986 • 87 citations

Effects of sulindac and ibuprofen in patients with cirrhosis and ascites

1986 • 85 citations

Sulindac

1982 • 79 citations

Reversible Acute Renal Insufficiency and Hyperkalemia Following Indomethacin Therapy

1981 • 77 citations

Role of prostaglandins in renin secretion

1981 • 76 citations

Interaction of cyclosporine A and nonsteroidal anti-inflammatory drugs on renal function in patients with rheumatoid arthritis

1992 • 74 citations

Minimal Change Glomerulopathy Associated With Nonsteroidal Antiinflammatory Drugs

1989 • 73 citations

Sulindac Reduces the Urinary Excretion of Prostaglandins and Impairs Renal Function in Cirrhosis with Ascites

1986 • 73 citations

Sulindac is not renal sparing in man

1985 • 71 citations

Preservation of the glomerular capillary ultrafiltration coefficient during rat nephrotoxic serum nephritis by a specific leukotriene D4 receptor antagonist.

1988 • 71 citations

Influence of non-steroidal anti-inflammatory drugs on diuretic treatment of mild to moderate essential hypertension.

1984 • 68 citations

Immunologic Effects of Nonsteroidal Anti-Inflammatory Drugs

1984 • 67 citations

Enhanced renal leukotriene production in murine lupus: Role of lipoxygenase metabolites

1991 • 67 citations

Acute renal effects of sulindac and indomethacin in chronic renal failure

1985 • 65 citations

Renal tubular arachidonic acid metabolism

1991 • 63 citations

Synthesis of hydroxyeicosatetraenoic acids and leukotrienes in rat nephrotoxic serum glomerulonephritis. Role of anti-glomerular basement membrane antibody dose, complement, and neutrophiles.

1988 • 60 citations

Effects of leukotrienes on isolated rat glomeruli and cultured mesangial cells

1986 • 59 citations

Effects of leukotriene D4 on glomerular dynamics in the rat

1987 • 55 citations

Increased leukotriene B4 synthesis in immune injured rat glomeruli.

1988 • 51 citations

Renal impairment associated with non-steroidal anti-inflammatory drugs.

1987 • 51 citations

Incidence of hyperkalaemia induced by indomethacin in a hospital population.

1985 • 50 citations

Eicosanoids modulate apical Ca(2+)-dependent K+ channels in cultured rabbit principal cells

1992 • 49 citations

The Regulation of Potassium Balance

1989 • 49 citations

Role of platelet activating factor in endotoxemic acute renal failure in the male rat.

1989 • 49 citations

Interaction of nonsteroidal anti-inflammatory drugs with antihypertensive and diuretic agents: Control of vascular reactivity by endogenous prostanoids

1986 • 47 citations

Biochemistry and pharmacology of renal arachidonic acid metabolism

1986 • 44 citations

Non-Steroidal Anti-Inflammatory Drugs and Blood Pressure

1982 • 42 citations

Ibuprofen-Associated Renal Dysfunction

1987 • 41 citations

Glomerular prostaglandins, angiotensin II, and nonsteroidal anti-inflammatory drugs

1986 • 39 citations

Renal effects of nonsteroidal anti-inflammatory drugs in chronic glomerular disease

1986 • 38 citations

Are prostaglandins proinflammatory, antiinflammatory, both or neither?

1991 • 37 citations

Renal metabolism of sulindac: functional implications.

1984 • 36 citations

Immune complex effects on glomerular eicosanoid production and renal hemodynamics

1987 • 35 citations

Vasoregulatory hormones and the hyperfiltration of diabetes

1988 • 35 citations

Sulindac and Indomethacin Suppress the Diuretic Action of Furosemide in Patients With Cirrhosis and Ascites: Evidence That Sulindac Affects Renal Prostaglandins

1985 • 35 citations

Cyclosporin A inhibits prostaglandin E2 formation by rat mesangial cells in culture

1989 • 33 citations

Prostaglandin E1 inhibits effector T cell induction and tissue damage in experimental murine interstitial nephritis.

1987 • 33 citations

Intravenous disodium etidronate therapy in Paget's disease of bone and hypercalcemia of malignancy: Effects on biochemical parameters and bone histomorphometry

1987 • 32 citations

Acute and chronic effects of sulindac on renal function in chronic renal disease

1985 • 32 citations

Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis

1990 • 32 citations

ENISOPROST IN RENAL TRANSPLANTATION1

1992 • 32 citations

Patterns of tubulo-interstitial damage associated with nonsteroidal antiinflammatory drugs.

1988 • 32 citations

Prostaglandin-E2 receptors in the rat kidney: Biochemical characterization and localization

1987 • 31 citations

Indomethacin-Induced Rises in Blood Pressure

1983 • 30 citations

Prostaglandin E1 suppresses macrophage infiltration and ameliorates injury in an experimental model of macrophage-dependent glomerulonephritis

1990 • 29 citations

Endothelin and eicosanoid synthesis in cultured mesangial cells

1990 • 28 citations

Sustained activation of PGE2 synthesis in mesangial cells cocultured with glomerular endothelial cells

1992 • 28 citations

Renal adrenergic effector mechanisms: glomerular sites for prostaglandin interaction

1988 • 26 citations

Effects of sulindac on renal function and prostaglandin synthesis in patients with moderate chronic renal insufficiency

1986 • 26 citations

LTB4 in nephrotoxic serum nephritis in rats

1989 • 25 citations

Implications of NSAID therapy in elderly patients.

1990 • 25 citations

The importance of arachidonate metabolism by immune and nonimmune cells.

1988 • 23 citations

Leukotriene D4 binding and signal transduction in rat glomerular mesangial cells

1989 • 21 citations

Mechanism of attenuated hydrochlorothiazide response during indomethacin administration

1987 • 20 citations

Ibuprofen-Associated Lipoid Nephrosis Without Interstitial Nephritis

1989 • 19 citations

The effects of naproxen and sulindac on renal function and their interaction with hydrochlorothiazide and piretanide in man.

1987 • 18 citations

Sulindac Kinetics and Effects on Renal Function and Prostaglandin Excretion in Renal Insufficiency

1989 • 17 citations

Use of Drugs in Patients with Renal Failure

1998 • 17 citations

Paradoxical exacerbation of leukocyte-mediated glomerulonephritis with cyclooxygenase inhibition

1992 • 13 citations

Effect of inhibitors of prostaglandin synthesis on the furosemide action in the loop Henle of rat kidney

1988 • 13 citations

EFFECTS OF NAPROXEN ON RENAL FUNCTION IN OLDER PATIENTS WITH MILD TO MODERATE RENAL DYSFUNCTION

1992 • 11 citations

Urinary eicosanoids and the assessment of glomerular inflammation.

1992 • 10 citations

Renal Prostaglandins, Effective Renal Plasma Flow and Glomerular Filtration Rate in Healthy Elderly Subjects

1992 • 10 citations

Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage

1986 • 9 citations

Indomethacin secretion in the isolated perfused proximal straight rabbit tubule. Evidence for two parallel transport mechanisms.

1988 • 8 citations

Potassium in cardiovascular and renal medicine : arrhythmias, myocardial infarction, and hypertension

1986 • 7 citations