Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas.

1989 • 511 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas. Activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor.

1988 • 324 citations

Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity.

1988 • 302 citations

Patterns of Human Tumor-Infiltrating Lymphocytes in 120 Human Cancers

1990 • 240 citations

Production of stable cytolytic T‐cell clones directed against autologous human melanoma

1987 • 209 citations

Presence on a human melanoma of multiple antigens recognized by autologous CTL

1989 • 180 citations

Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.

1987 • 179 citations

LYMPHOCYTIC INFILTRATION IN GLIOMAS: EVIDENCE OF POSSIBLE HOST RESISTANCE

1971 • 170 citations

Predominant Expression of T Cell Receptor V _α 7 in Tumor-Infiltrating Lymphocytes of Uveal Melanoma

1990 • 169 citations

Abnormal T lymphocyte subpopulations in patients with B cell chronic lymphocytic leukemia: an analysis by monoclonal antibodies.

1982 • 160 citations

Cytotoxic T cell clones isolated from ovarian tumor-infiltrating lymphocytes recognize multiple antigenic epitopes on autologous tumor cells.

1991 • 159 citations

Histology and prognosis in malignant melanoma

1969 • 152 citations

Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation.

1991 • 138 citations

Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens

1981 • 105 citations

Characterization of a Human Renal Cell Carcinoma Specific Cytotoxic CD8+ T Cell Line

1992 • 100 citations

Tumor cytolysis by lymphocytes infiltrating ovarian malignant ascites.

1991 • 95 citations

Characterization of the cytolytic activity of CD4+ and CD8+ tumor-infiltrating lymphocytes in human renal cell carcinoma.

1990 • 91 citations

Cellular reaction to choriocarcinoma

1969 • 82 citations

Large-scale expansion in interleukin-2 of tumor-infiltrating lymphocytes from patients with ovarian carcinoma for adoptive immunotherapy

1994 • 74 citations

Autologous Tumor-Specific Cytotoxicity of Tumor-Infiltrating Lymphocytes Derived from Human Renal Cell Carcinoma

1991 • 64 citations

Selective expansion of a specific anti‐tumor CD8⁺ cytotoxic T lymphocyte clone in the bulk culture of tumor‐infiltrating lymphocytes from a melanoma patient: Cytotoxic activity and T cell receptor gene rearrangements

1990 • 58 citations

Relationship of tumor leucocytic infiltration to host defense mechanisms and prognosis

1984 • 52 citations

The T-cell receptor V beta gene usage in tumor-infiltrating lymphocytes and blood of patients with hepatocellular carcinoma.

1992 • 52 citations

Human T cell antigens involved in cytotoxicity against allogeneic or autologous chemically modified targets. Association of the Leu 2a/T8 antigen with effector‐target cell binding and of the T3/Leu 4 antigen with triggering

1984 • 47 citations

γ/δ T cell antigen receptors expressed on tumor‐infiltrating lymphocytes from patients with solid tumors

1992 • 42 citations

Human autologous tumor-specific T cells in malignant melanoma

1991 • 37 citations

Til from renal‐cell carcinoma: Restimulation with tumor influences proliferation and cytolytic activity

1990 • 36 citations

Immunohistochemical detection of major histocompatibility complex antigens and quantitative analysis of tumour-infiltrating mononuclear cells in renal cell cancer

1990 • 35 citations

Oligoclonal T lymphocytes infiltrating human lung cancer tissues

1991 • 31 citations

Expression of histocompatibility antigens and characterisation of mononuclear cell infiltrates in human renal cell carcinomas

1987 • 30 citations

Development of the Non‐Palindromic Adaptor Polymerase Chain Reaction (NPA‐PCR) for the Amplification of Alpha‐and Beta‐Chain T‐Cell Receptor cDNAs

1992 • 28 citations

Clonal analysis of lymphocytes from tumor, peripheral blood, and nontumorous kidney in primary renal cell carcinoma.

1990 • 27 citations

Lymphokine mRNA profile and functional analysis of a human CD4+ clone with unique antitumor specificity isolated from renal cell carcinoma ascitic fluid

1990 • 26 citations

Novel immunologic strategies in ovarian carcinoma

1992 • 22 citations

Lymphokine production by human melanoma tumor-infiltrating lymphocytes

1992 • 18 citations

Rationale for immunotherapy of renal cell carcinoma

1990 • 16 citations

Distinct regulatory effects of IL-4 and TNF-alpha during CD3-dependent and CD3-independent initiation of human T-cell activation.

1989 • 14 citations

Regulatory effects of interleukin-7 on renal tumor infiltrating lymphocytes

1992 • 13 citations

The Effects of Interleukin-6 on Tumor-Infiltrating Lymphocytes Derived from Human Renal Cell Cancer

1991 • 8 citations

Recombinant Interleukin-2-Expanded Tumor Infiltrating Lymphocytes from Human Renal Cell Cancer Do Not Exhibit Autologous Tumor Cell-Specific Cytotoxicity

1991 • 6 citations

Modulation of Tumor-Infiltrating Lymphocytes Derived from Human Renal Cell Carcinoma by Interleukin-4

1992 • 6 citations