Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity.

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

1985 • 2,616 citations

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli

1984 • 600 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Successful immunotherapy of murine experimental hepatic metastases with lymphokine-activated killer cells and recombinant interleukin 2.

1985 • 376 citations

Functional properties of tumor-infiltrating and blood lymphocytes in patients with solid tumors: effects of tumor cells and their supernatants on proliferative responses of lymphocytes.

1986 • 319 citations

Lymphokine-activated killer cells: A new approach to immunotherapy of cancer

1985 • 314 citations

In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors.

1980 • 264 citations

Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas.

1986 • 259 citations

Functional analysis of mononuclear cells infiltrating into tumors: lysis of autologous human tumor cells by cultured infiltrating lymphocytes.

1987 • 173 citations

The adoptive immunotherapy of cancer using lymphokine activated killer cells and recombinant interleukin-2

1986 • 145 citations

Depression of natural killer cytotoxic activity in lymphocytes infiltrating human pulmonary tumors.

1985 • 129 citations

Adoptive immunotherapy of cancer: accomplishments and prospects.

1984 • 120 citations

Human tumour—lymphocyte interaction in vitro. V. Comparison of the reactivity of tumour‐infiltrating, blood and lymph‐node lymphocytes with autologous tumour cells

1977 • 119 citations

Murine lymphokine-activated killer (LAK) cells: phenotypic characterization of the precursor and effector cells.

1986 • 108 citations

Quantitation of proliferative and cytotoxic precursor cells directed against human tumours: Limiting dilution analysis in peripheral blood and at the tumour site

1982 • 90 citations

Adjuvant immunotherapy of established murine renal cancer by interleukin 2-stimulated cytotoxic lymphocytes.

1986 • 72 citations

Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity

1981 • 67 citations

Cytological and functional analysis of inflammatory infiltrates in human malignant tumors

1980 • 49 citations

Separation and Characteristics of Tumor-Infiltrating Lymphocytes in Man

1980 • 46 citations

Effect of a streptococcal preparation (OK432) on natural killer activity of tumour-associated lymphoid cells in human ovarian carcinoma and on lysis of fresh ovarian tumour cells

1983 • 30 citations

Cultured human T-cell lines kill autologous solid tumours

1981 • 27 citations

Supernatant derived from a human hepatocellular carcinoma cell line (PLC/PRF/5) activates a population of T-suppressor cells

1983 • 9 citations