MMP-13 Plays a Role in Keratinocyte Migration, Angiogenesis, and Contraction in Mouse Skin Wound Healing

Cutaneous Wound Healing

1999 • 5,878 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

Robbins pathologic basis of disease

1989 • 1,872 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Pathophysiology of acute wound healing

2007 • 1,345 citations

Matrix metalloproteinases: they're not just for matrix anymore!

2001 • 1,257 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

2000 • 792 citations

An Assay for Transforming Growth Factor-β Using Cells Transfected with a Plasminogen Activator Inhibitor-1 Promoter-Luciferase Construct

1994 • 749 citations

Robbins Pathologic Basis of Disease

1999 • 711 citations

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

2004 • 581 citations

Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κB

1998 • 500 citations

Transforming Growth Factor-β1 Promotes the Morphological and Functional Differentiation of the Myofibroblast

2000 • 466 citations

Matrix metalloproteinases in repair

1999 • 375 citations

Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF‐induced angiogenesis

2001 • 360 citations

Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.

1992 • 355 citations

Matrix Metalloproteinases Cleave Connective Tissue Growth Factor and Reactivate Angiogenic Activity of Vascular Endothelial Growth Factor 165

2002 • 348 citations

Matrix Metalloproteinases (MMPs) and Their Physiological Inhibitors (TIMPs) Are Differentially Expressed during Excisional Skin Wound Repair

1998 • 331 citations

Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice

2005 • 316 citations

Matrix Metalloproteinase Gelatinase B (MMP-9) Coordinates and Effects Epithelial Regeneration

2002 • 291 citations

Distinct Populations of Stromal Cells Express Collagenase-3 (MMP-13) and Collagenase-1 (MMP-1) in Chronic Ulcers but Not in Normally Healing Wounds

1997 • 289 citations

A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues.

1994 • 283 citations

Functional overlap between two classes of matrix-degrading proteases in wound healing

1999 • 273 citations

Increased inflammation delays wound healing in mice deficient in collagenase‐2 (MMP‐8)

2007 • 269 citations

Joint Diseases and Matrix Metalloproteinases: A Role for MMP-13

2008 • 260 citations

Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation

2001 • 237 citations

Impaired Wound Contraction in Stromelysin-1–Deficient Mice

1999 • 232 citations

Expression of Matrix Metalloproteinases during Rat Skin Wound Healing: Evidence that Membrane Type-1 Matrix Metalloproteinase Is a Stromal Activator of Pro-Gelatinase A

1997 • 225 citations

Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)-mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9

1998 • 220 citations

Identification of Candidate Angiogenic Inhibitors Processed by Matrix Metalloproteinase 2 (MMP-2) in Cell-Based Proteomic Screens: Disruption of Vascular Endothelial Growth Factor (VEGF)/Heparin Affin Regulatory Peptide (Pleiotrophin) and VEGF/Connective Tissue Growth Factor Angiogenic Inhibitory Complexes by MMP-2 Proteolysis

2007 • 197 citations

Authentic Matrix Vesicles Contain Active Metalloproteases (MMP)

2001 • 184 citations

Matrix Metalloproteinase 2 (Gelatinase A) Is Related to Migration of Keratinocytes

1999 • 176 citations

Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds

2004 • 152 citations

Dynamics of the matrix metalloproteinases MMP‐1 and MMP‐8 in acute open human dermal wounds

1998 • 146 citations

Diminished corneal angiogenesis in gelatinase A‐deficient mice

2001 • 141 citations

Discovery of Chemokine Substrates for Matrix Metalloproteinases by Exosite Scanning: A New Tool for Degradomics

2002 • 134 citations

The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells

2007 • 127 citations

ADAM28 Is Overexpressed in Human Breast Carcinomas: Implications for Carcinoma Cell Proliferation through Cleavage of Insulin-like Growth Factor Binding Protein-3

2006 • 116 citations

The role of the matrix metalloproteinases during in vitro vessel formation.

2002 • 103 citations

Epidermal Development and Wound Healing in Matrix Metalloproteinase 13-Deficient Mice

2005 • 92 citations

Basic fibroblast growth factor promotes apoptosis and suppresses granulation tissue formation in acute incisional wounds

2004 • 90 citations

TNF-α regulates epithelial expression of MMP-9 and integrin αvβ6 during tumour promotion. A role for TNF-α in keratinocyte migration?

2004 • 89 citations

Basic fibroblast growth factor stimulates human keratinocyte motility by Rac activation

2006 • 76 citations

Stem cell-related cardiac gene expression early after murine myocardial infarction

2006 • 75 citations

Expression of human collagenase-3 (MMP-13) by fetal skin fibroblasts is induced by transforming growth factor beta via p38 mitogen-activated protein kinase.

2001 • 72 citations

Long-term outcome study of growth factor-treated pressure ulcers

2001 • 67 citations

Severely Impaired Wound Healing in the Collagenase-Resistant Mouse

2003 • 67 citations

Matrilysin-2 (Matrix Metalloproteinase-26) Is Upregulated in Keratinocytes During Wound Repair and Early Skin Carcinogenesis

2005 • 66 citations

Matrix Metalloproteinase-19 Expression in Dermal Wounds and by Fibroblasts in Culture

2003 • 64 citations

Comparison of Mouse Matrix Metalloproteinase 13 Expression in Free-Electron Laser and Scalpel Incisions During Wound Healing

2003 • 58 citations

Matrix Metalloproteinase Inhibitor BB-3103 Unlike the Serine Proteinase Inhibitor Aprotinin Abrogates Epidermal Healing of Human Skin Wounds Ex Vivo11Presented in part at the 10th Annual Meeting of the European Tissue Repair Society (ETRS) May 24–28, 2000 in Brussels, Belgium and at the 35th Congress of the European Society for Surgical Research (ESSR) June 1–3, 2000 in Malmö, Sweden and abstract published in Eur Surg Res 32 (Suppl. 1):2–3, 2000.

2002 • 58 citations

Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-xL reduction thereby enhancing UV-light induced apoptosis

2005 • 49 citations

Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis

2005 • 46 citations

Increased Migration of Murine Keratinocytes Under Hypoxia Is Mediated by Induction of Urokinase Plasminogen Activator

2002 • 33 citations

Vascular expression of matrix metalloproteinase-13 (collagenase-3) in basal cell carcinoma

2003 • 22 citations

Original Research Articles – Basic Science: Variable impairment of wound healing in the heterozygous collagenase‐resistant mouse

2005 • 11 citations