ADAM28 Is Overexpressed in Human Breast Carcinomas: Implications for Carcinoma Cell Proliferation through Cleavage of Insulin-like Growth Factor Binding Protein-3

New functions for the matrix metalloproteinases in cancer progression

2002 • 5,937 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

2002 • 1,717 citations

Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor

1995 • 1,361 citations

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

2000 • 1,200 citations

ADAMs: key components in EGFR signalling and development

2005 • 1,056 citations

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

2003 • 1,052 citations

The Insulin-Like Growth Factor-Binding Protein (IGFBP) Superfamily*

1999 • 1,008 citations

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

2002 • 727 citations

ADAMs: modulators of cell–cell and cell–matrix interactions

2003 • 406 citations

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

1994 • 345 citations

The IGF system and breast cancer.

2001 • 316 citations

Tyrosine kinase signalling in breast cancer: Epidermal growth factor receptor and c-Src interactions in breast cancer

2000 • 315 citations

ADAM 12-S Cleaves IGFBP-3 and IGFBP-5 and Is Inhibited by TIMP-3

2000 • 309 citations

Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects

2005 • 305 citations

Cell–matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation

2004 • 288 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Insulin-like growth factor binding protein proteolysis

2003 • 235 citations

MT1-MMP and MMP-7 in invasion and metastasis of human cancers.

2003 • 234 citations

Cysteine-Rich Domain of Human ADAM 12 (Meltrin α) Supports Tumor Cell Adhesion

1999 • 209 citations

Viper Venom Disintegrins and Related Molecules

1998 • 189 citations

The Matrix Metalloproteinase-9 Regulates the Insulin-like Growth Factor-triggered Autocrine Response in DU-145 Carcinoma Cells

1999 • 186 citations

Catalytic Activity of ADAM8, ADAM15, and MDC-L (ADAM28) on Synthetic Peptide Substrates and in Ectodomain Cleavage of CD23

2003 • 176 citations

Nectin-4, a New Serological Breast Cancer Marker, Is a Substrate for Tumor Necrosis Factor-α-converting Enzyme (TACE)/ADAM-17

2005 • 153 citations

Matrix Metalloproteinase-7 Facilitates Insulin-Like Growth Factor Bioavailability through Its Proteinase Activity on Insulin-Like Growth Factor Binding Protein 3

2004 • 151 citations

Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo

2004 • 150 citations

ADAM12 Is Selectively Overexpressed in Human Glioblastomas and Is Associated with Glioblastoma Cell Proliferation and Shedding of Heparin-Binding Epidermal Growth Factor

2004 • 150 citations

Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.

2002 • 148 citations

Expression of ADAM‐9 mRNA and protein in human breast cancer

2003 • 138 citations

A Role for ADAM12 in Breast Tumor Progression and Stromal Cell Apoptosis

2005 • 138 citations

Breast cell invasive potential relates to the myoepithelial phenotype

2003 • 127 citations

Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells.

2003 • 124 citations

ADAM28 is activated by MMP-7 (matrilysin-1) and cleaves insulin-like growth factor binding protein-3

2004 • 118 citations

Matrix Metalloproteinase 19 Regulates Insulin-like Growth Factor-mediated Proliferation, Migration, and Adhesion in Human Keratinocytes through Proteolysis of Insulin-like Growth Factor Binding Protein-3

2003 • 115 citations

A prospective study of serum insulin-like growth factor-I (IGF-I), IGF-II, IGF-binding protein-3 and breast cancer risk

2005 • 114 citations

Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells

1991 • 97 citations

TGF-beta signaling in mammary gland development and tumorigenesis.

2001 • 95 citations

L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro.

1997 • 92 citations

ADAMs(A Disintegrin and Metalloproteinase) Messenger RNA Expression inHelicobacter pylori–Infected, Normal, and Neoplastic Gastric Mucosa

2002 • 90 citations

ADAM28 is overexpressed in human non-small cell lung carcinomas and correlates with cell proliferation and lymph node metastasis

2005 • 84 citations

Catalytic activity of ADAM28

2001 • 72 citations

MDC-L, a Novel Metalloprotease Disintegrin Cysteine-rich Protein Family Member Expressed by Human Lymphocytes

1999 • 70 citations

Short Hairpin RNA–Mediated Inhibition of Matrix Metalloproteinase-1 in MDA-231 Cells: Effects on Matrix Destruction and Tumor Growth

2005 • 63 citations

Cell density-dependent regulation of matrix metalloproteinase and TIMP expression in differently tumorigenic breast cancer cell lines

2005 • 44 citations

Activation of pro‐MMP‐2 mediated by MT1‐MMP in human salivary gland carcinomas: possible regulation of pro‐MMP‐2 activation by TIMP‐2

2004 • 39 citations

Insulin-Like Growth Factor (IGF)-I and IGF-II Serum Concentrations in Patients with Benign and Malignant Breast Lesions

2004 • 37 citations

Development of In Situ Zymography to Localize Active Matrix Metalloproteinase-7 (Matrilysin-1)

2005 • 11 citations