Individuality in Early Eukaryotes and the Consequences for Matazoan Development

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

The Evolution of Sex

1978 • 3,074 citations

Protein Oxidation and Aging

1992 • 2,687 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Sex and evolution.

1975 • 2,162 citations

The aging process.

1981 • 1,871 citations

The Units of Selection

1970 • 1,857 citations

Gene Activity in Early Development

1968 • 1,725 citations

DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems

1991 • 1,555 citations

Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in Drosophila melanogaster

1994 • 1,461 citations

Princeton University Press

2017 • 1,414 citations

Symbiosis in cell evolution

1981 • 1,386 citations

Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?

1992 • 1,268 citations

The evolution of individuality

1987 • 1,231 citations

Calcium Channels, Stores, and Oscillations

1990 • 1,208 citations

Range of Messenger Action of Calcium Ion and Inositol 1,4,5-Trisphosphate

1992 • 1,144 citations

Inositol Trisphosphate and Calcium Signaling

1995 • 1,036 citations

Molecular biology of the cell

1983 • 1,007 citations

The major evolutionary transitions

1995 • 976 citations

Respiratory Enzymes in Oxidative Phosphorylation

1958 • 900 citations

Initiation of Runaway Cell Death in an Arabidopsis Mutant by Extracellular Superoxide

1996 • 845 citations

Too Many Rodent Carcinogens: Mitogenesis Increases Mutagenesis

1990 • 773 citations

The molecular biology of the cell

1986 • 687 citations

β-Amyloid-mediated vasoactivity and vascular endothelial damage

1996 • 686 citations

Monophyletic Origins of the Metazoa: an Evolutionary Link with Fungi

1993 • 673 citations

The Early Evolution of Eukaryotes: A Geological Perspective

1992 • 673 citations

The Endosymbiont Hypothesis Revisited

1992 • 586 citations

Determining Divergence Times of the Major Kingdoms of Living Organisms with a Protein Clock

1996 • 584 citations

The Energy-linked Reaction of Calcium with Mitochondria

1965 • 556 citations

Chemical carcinogenesis: too many rodent carcinogens.

1990 • 498 citations

Mitochondrial calcium transport

1982 • 486 citations

Ecology and evolution in anoxic worlds

1996 • 465 citations

Competition and Diversity in Herbaceous Vegetation

1973 • 438 citations

Has the endosymbiont hypothesis been proven?

1982 • 425 citations

Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes

1995 • 425 citations

Patterns and problems of development

1941 • 423 citations

The Early Evolution of Metazoa and the Significance of Problematic Taxa.

1993 • 391 citations

Origin of Bilaterian Body Plans: Evolution of Developmental Regulatory Mechanisms

1995 • 379 citations

Relation between mitochondrial calcium transport and control of energy metabolism

1985 • 362 citations

Invertebrate relationships: patterns in animal evolution

1990 • 316 citations

Invertebrate Relationships

1990 • 315 citations

Origin and Evolution of Mitochondrial DNA

1989 • 311 citations

Problems And Paradigms: Metaphors and the role of genes in development

1990 • 290 citations

Has the endosymbiont hypothesis been proven?

1982 • 281 citations

The Simultaneous Symbiotic Origin of Mitochondria, Chloroplasts, and Microbodies

1987 • 274 citations

Role of Intracellular Calcium in NI-35-Evoked Collapse of Neuronal Growth Cones

1993 • 271 citations

Oxidative influence on development and differentiation: An overview of a free radical theory of development

1989 • 270 citations

The Demise of a Phylum of Protists: Phylogeny of Myxozoa and Other Parasitic Cnidaria

1995 • 263 citations

Cyclic ADP-Ribose: a New Way to Control Calcium

1993 • 260 citations

Growth regulation of the vascular system: evidence for a metabolic hypothesis

1990 • 258 citations

The making of a fly

1992 • 258 citations

EVOLUTION OF THE PEROXISOME

1969 • 244 citations

CONTROL OF ELECTRON FLUX THROUGH THE RESPIRATORY CHAIN IN MITOCHONDRIA AND CELLS

1987 • 240 citations

Organelle Genes and Genomes

1994 • 239 citations

Do mitochondrial DNA fragments promote cancer and aging?

1988 • 224 citations

Mitochondria and Microsomes

1982 • 223 citations

Optical Method

1991 • 216 citations

Embryology and Genetics

1934 • 202 citations

Peroxisome biogenesis revisited

1989 • 189 citations

Molecular Therapies for Vascular Diseases

1996 • 173 citations

Nucleotide sequence of the Dictyostelium discoideum small-subunit ribosomal ribonucleic acid inferred from the gene sequence: evolutionary implications

1983 • 173 citations

Pronounced structural similarities between the small subunit ribosomal RNA genes of wheat mitochondria and Escherichia coli.

1984 • 127 citations

Oxidative Damage to Behavior During Aging

1991 • 112 citations

Generic physical mechanisms of tissue morphogenesis: A common basis for development and evolution

1994 • 111 citations

The Mating Activities of Balloon Flies

1955 • 96 citations

Ca2+ signaling mechanisms of vascular endothelial cells and their role in oxidant-induced endothelial cell dysfunction

1992 • 86 citations

Sex and Death in Protozoa

1988 • 73 citations

THE DEVELOPMENTAL ROLE OF THE EXTRACELLULAR MATRIX SUGGESTS A MONOPHYLETIC ORIGIN OF THE KINGDOM ANIMALIA

1993 • 68 citations

Polarity and reorganization of the endoplasmic reticulum during fertilization and ooplasmic segregation in the ascidian egg.

1993 • 67 citations

Phylogenetic analysis of the thiolase family. Implications for the evolutionary origin of peroxisomes

1992 • 56 citations

Mitochondria and microsomes

1956 • 52 citations

The peroxisome: a vital organelle

1996 • 52 citations

CLADISTIC ANALYSIS OF METAZOAN RELATIONSHIPS: A REAPPRAISAL

1993 • 50 citations

PERSPECTIVE A UNITS‐OF‐EVOLUTION PERSPECTIVE ON THE ENDOSYMBIONT THEORY OF THE ORIGIN OF THE MITOCHONDRION

1995 • 45 citations

The determination of spatial pattern inDictyostelium discoideum

1992 • 37 citations

God in the details

1996 • 37 citations

Experimental heterochrony in hydractiniid hydroids: Why mechanisms matter

1993 • 36 citations

Rampant Parallelism: An Appraisal of the Use of Nonuniversal Derived Character States in Phylogenetic Reconstruction

1989 • 33 citations

THE AXIAL GRADIENTS IN HYDROZOA

1919 • 30 citations

The Developmental Role of the Extracellular Matrix Suggests a Monophyletic Origin of the Kingdom Animalia

1993 • 30 citations

METAZOAN RELATIONSHIP: A REBUTTAL

1994 • 28 citations

Metazoan Relationship: A Rebuttal

1994 • 27 citations

PERSPECTIVE: THE EVOLUTIONARY BIOLOGY OF AGING, SEXUAL REPRODUCTION, AND DNA REPAIR

1993 • 27 citations

Treatment with 2,4-dinitrophenol mimics ontogenetic and phylogenetic changes in a hydractiniid hydroid.

1992 • 26 citations

1 alpha,25-(OH)2 vitamin D3 enhances expression of the genes encoding Ca(2+)-binding proteins MRP-8 and MRP-14

1992 • 24 citations

Generic physical mechanisms of morphogenesis and pattern formation as determinants in the evolution of multicellular organization

1992 • 24 citations

THE AXIAL GRADIENTS IN HYDROZOA

1919 • 24 citations

5. Manometers, Tissue Slices, and Intermediary Metabolism

1992 • 23 citations

Perspective: A Units-of-Evolution Perspective on the Endosymbiont Theory of the Origin of the Mitochondrion

1995 • 20 citations

The peroxisome: A vital organelle

1996 • 20 citations

Cuvier meets Watson and Crick: the utility of molecules as classical homologies

1991 • 15 citations

The Evolutionary Biology of Aging, Sexual Reproduction, and DNA Repair

1993 • 15 citations

The evolution of life's complexity

1995 • 12 citations

Reversible Abolition of Normal Morphology in Hydra

1973 • 10 citations

THE BEHAVIOR OF CATALASE AND PEROXIDASE IN COUPLED REACTIONS

1969 • 7 citations

Sixty years of biology

1996 • 7 citations