Changes in muscarinic cholinergic, PCP, GABAA, D1, and 5-HT2A receptor binding, but not in benzodiazepine receptor binding in the brains of aged rats

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1983 • 3,028 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

1987 • 1,031 citations

A new murine model of accelerated senescence

1981 • 855 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

Overview of depression and psychosis in Alzheimer's disease

1989 • 665 citations

Spatial learning and motor deficits in aged rats

1984 • 509 citations

Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues

1987 • 341 citations

Protein kinase C injection into hippocampal pyramidal cells elicits features of long term potentiation

1987 • 340 citations

The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system

1987 • 318 citations

Brain cholinergic dysfunction and memory in aged rats

1980 • 257 citations

Movement Disorders of Aged Rats: Reversal by Dopamine Receptor Stimulation

1979 • 207 citations

What is the nature of the role of the serotonergic nervous system in learning and memory: Prospects for development of an effective treatment strategy for senile dementia

1988 • 181 citations

Long-Term Neuropathological and Neurochemical Effects of Nucleus Basalis Lesions in the Rat

1987 • 169 citations

Age-related alterations in neurotransmitter receptors: An electrophysiological and biochemical analysis

1981 • 167 citations

Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.

1987 • 125 citations

Influence of age on NMDA receptor complex in rat brain studied by in vitro autoradiography.

1990 • 76 citations

Different neuronal location of [3H]SCH 23390 binding sites in pars reticulata and pars compacta of the substantia nigra in the rat

1986 • 75 citations

The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat

1993 • 69 citations

Age-related decrease of the NMDA receptor-mediated noradrenaline release in rat hippocampus and partial restoration by D-cycloserine

1993 • 68 citations

[³H]Norepinephrine Release from Hippocampal Slices Is an In Vitro Biochemical Tool for Investigating the Pharmacological Properties of Excitatory Amino Acid Receptors

1987 • 51 citations

The muscarinic stimulation of phospholipid labeling in hippocampus is independent of its cholinergic input

1980 • 50 citations

Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.

1991 • 41 citations

Staurosporine facilitates recovery from the basal forebrain-lesion-induced impairment of learning and deficit of cholinergic neuron in rats.

1991 • 36 citations

Age‐Related Loss of t‐[³⁵S]Butylbicyclophosphorothionate Binding to the γ‐Aminobutyric Acid_A Receptor‐Coupled Chloride Ionophore in Rat Cerebral Cortex

1989 • 31 citations

Altered dopamine receptor mediated signal transmission in the striatum of aged rats

1993 • 28 citations

Age-related changes in receptor-mediated phosphoinositide hydrolysis in various regions of rat brain

1991 • 25 citations

Aged-Related Changes in Learning and Memory, Choline Acetyltransferase Activity and Number of Neuronal Cells in Rats.

1991 • 25 citations

Influence of age on N‐methyl‐D‐aspartate antagonist binding sites in the rat brain studied by in vitro autoradiography

1991 • 25 citations

Effects of propentofylline, a NGF synthesis stimulator, on alterations in muscarinic cholinergic receptors induced by basal forebrain lesion in rats

1993 • 23 citations

Development of tolerance to anxiolytic effects of chlordiazepoxide in elevated plus-maze test and decrease of GABAA receptors

1993 • 16 citations

Characteristics of muscarinic cholinergic, γ-aminobutyric acidA and phencyclidine receptors in spontaneously epileptic rats; in vitro quantitative autoradiographic analysis

1991 • 16 citations

Cerebellar GABAA and benzodiazepine receptor characteristics in young and aged mice

1988 • 14 citations

Effect of naftidrofuryl oxalate on 5-HT2 receptors in mouse brain: evaluation based on quantitative autoradiography and head-twitch response

1992 • 8 citations